Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Tetiana Gren"'
Autor:
Daniel Oves-Costales, Tetiana Gren, Eva Baggesgaard Sterndorff, Jesús Martín, Francisco Javier Ortiz-López, Tue S. Jørgensen, Xinglin Jiang, Fernando Román-Hurtado, Fernando Reyes, Olga Genilloud, Tilmann Weber
Publikováno v:
Synthetic and Systems Biotechnology, Vol 8, Iss 2, Pp 206-212 (2023)
Globomycin is a cyclic lipodepsipeptide originally isolated from several Streptomyces species which displays strong and selective antibacterial activity against Gram-negative pathogens. Its mode of action is based on the competitive inhibition of the
Externí odkaz:
https://doaj.org/article/e800521b7d924a0689d8306ad9d65e4a
Autor:
Tetiana Gren, Christopher M. Whitford, Omkar S. Mohite, Tue S. Jørgensen, Eftychia E. Kontou, Julie B. Nielsen, Sang Yup Lee, Tilmann Weber
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Streptomyces griseofuscus DSM 40191 is a fast growing Streptomyces strain that remains largely underexplored as a heterologous host. Here, we report the genome mining of S. griseofuscus, followed by the detailed exploration of its phenotype,
Externí odkaz:
https://doaj.org/article/1d6bc7c1088b4caf88db11a4fa49fa8b
Autor:
Borys Dolya, Olena Hryhorieva, Khrystyna Sorochynska, Maria Lopatniuk, Iryna Ostash, Vasylyna-Marta Tseduliak, Eva Baggesgaard Sterndorff, Tue Sparholt Jørgensen, Tetiana Gren, Yuriy Dacyuk, Tilmann Weber, Andriy Luzhetskyy, Victor Fedorenko, Bohdan Ostash
Publikováno v:
Microorganisms, Vol 11, Iss 5, p 1176 (2023)
Streptomyces albidoflavus J1074 is a popular platform to discover novel natural products via the expression of heterologous biosynthetic gene clusters (BGCs). There is keen interest in improving the ability of this platform to overexpress BGCs and, c
Externí odkaz:
https://doaj.org/article/074ec5aa5e7f49d4be3db5ee7c5b30f6
Autor:
Charlotte Beck, Tetiana Gren, Francisco Javier Ortiz-López, Tue Sparholt Jørgensen, Daniel Carretero-Molina, Jesús Martín Serrano, José R. Tormo, Daniel Oves-Costales, Eftychia E. Kontou, Omkar S. Mohite, Erik Mingyar, Evi Stegmann, Olga Genilloud, Tilmann Weber
Publikováno v:
Molecules, Vol 26, Iss 21, p 6580 (2021)
Streptomyces are well-known producers of a range of different secondary metabolites, including antibiotics and other bioactive compounds. Recently, it has been demonstrated that “silent” biosynthetic gene clusters (BGCs) can be activated by heter
Externí odkaz:
https://doaj.org/article/86badcd3f9eb4ba6bb5883784ca814da
Autor:
Timo Wolf, Julian Droste, Tetiana Gren, Vera Ortseifen, Susanne Schneiker-Bekel, Till Zemke, Alfred Pühler, Jörn Kalinowski
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-14 (2017)
Abstract Background Acarbose is used in the treatment of diabetes mellitus type II and is produced by Actinoplanes sp. SE50/110. Although the biosynthesis of acarbose has been intensively studied, profound knowledge about transcription factors involv
Externí odkaz:
https://doaj.org/article/90a21bf5be4f444882987be5ac13cdde
Autor:
Julie B. Nielsen, Tetiana Gren, Omkar S. Mohite, Tue S. Jørgensen, Andreas K. Klitgaard, Anna-Sophie Mourched, Kai Blin, Daniel Oves-Costales, Olga Genilloud, Thomas O. Larsen, David Tanner, Tilmann Weber, Charlotte H. Gotfredsen, Pep Charusanti
Publikováno v:
ACS Chemical Biology. 17:2411-2417
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25b7cfa93b8bc056f36f7d03461ba332
https://doi.org/10.1021/acschembio.2c00480
https://doi.org/10.1021/acschembio.2c00480
Autor:
Christopher M. Whitford, Peter Gockel, David Faurdal, Tetiana Gren, Renata Sigrist, Tilmann Weber
Type I CRISPR systems are widespread in bacteria and archaea. The main differences compared to more widely applied type II systems are multi-effector CASCADE needed for crRNA processing and target recognition, as well as the processive nature of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07318b628f574799016657597675a81d
https://doi.org/10.1101/2023.05.09.539971
https://doi.org/10.1101/2023.05.09.539971
Autor:
Daniel Carretero-Molina, Francisco Javier Ortiz-López, Tetiana Gren, Daniel Oves-Costales, Jesús Martín, Fernando Román-Hurtado, Tue Sparholt Jørgensen, Mercedes de la Cruz, Caridad Díaz, Francisca Vicente, Kai Blin, Fernando Reyes, Tilmann Weber, Olga Genilloud
Publikováno v:
Organic Chemistry Frontiers. 9:462-470
Gargantulides B and C are among the most complex bacterial polyketides discovered so far. A combination of NMR and genome-based bioinformatics analyses allowed us to complete and revise the absolute stereochemistry of the entire gargantulide family.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04c21c83417ceb99d6b341429f7ed969
https://doi.org/10.1039/d1qo01480c
https://doi.org/10.1039/d1qo01480c
Autor:
Emil Thomsen, Francisco Javier Ortiz-López, Tetiana Gren, Xinglin Jiang, Pep Charusanti, Tue Sparholt Jørgensen, Kai Blin, Daniel Oves-Costales, Eftychia E. Kontou, Fernando Reyes, Olga Genilloud, Mercedes de la Cruz, Caridad Díaz, Tilmann Weber
Publikováno v:
ACS Chemical Biology. 16:1456-1468
Actinobacteria have been a rich source of novel, structurally complex natural products for many decades. Although the largest genus is Streptomyces, from which the majority of antibiotics in current and past clinical use were originally isolated, oth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e982a789306f9079cb780cede4a5185
https://doi.org/10.1021/acschembio.1c00318
https://doi.org/10.1021/acschembio.1c00318
Autor:
Omkar Satyavan Mohite, Tue Sparholt Jørgensen, Jesús Martín Serrano, Tetiana Gren, Eftychia E. Kontou, Daniel Carretero-Molina, Olga Genilloud, Francisco Javier Ortiz-López, José R. Tormo, Daniel Oves-Costales, Evi Stegmann, Tilmann Weber, Erik Mingyar, Charlotte Beck
Publikováno v:
Molecules
Beck, C, Gren, T, Ortiz-López, F J, Jørgensen, T S, Carretero-Molina, D, Serrano, J M, Tormo, J R, Oves-Costales, D, Kontou, E E, Mohite, O S, Mingyar, E, Stegmann, E, Genilloud, O & Weber, T 2021, ' Activation and identification of a griseusin cluster in streptomyces sp. Ca-256286 by employing transcriptional regulators and multi-omics methods ', Molecules, vol. 26, 6580 . https://doi.org/10.3390/molecules26216580
Molecules, Vol 26, Iss 6580, p 6580 (2021)
Volume 26
Issue 21
Beck, C, Gren, T, Ortiz-López, F J, Jørgensen, T S, Carretero-Molina, D, Serrano, J M, Tormo, J R, Oves-Costales, D, Kontou, E E, Mohite, O S, Mingyar, E, Stegmann, E, Genilloud, O & Weber, T 2021, ' Activation and identification of a griseusin cluster in streptomyces sp. Ca-256286 by employing transcriptional regulators and multi-omics methods ', Molecules, vol. 26, 6580 . https://doi.org/10.3390/molecules26216580
Molecules, Vol 26, Iss 6580, p 6580 (2021)
Volume 26
Issue 21
Streptomyces are well-known producers of a range of different secondary metabolites, including antibiotics and other bioactive compounds. Recently, it has been demonstrated that “silent” biosynthetic gene clusters (BGCs) can be activated by heter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf3238b84f39676b4bd01b7f05c90e8
http://europepmc.org/articles/PMC8588249
http://europepmc.org/articles/PMC8588249