Forming megakaryocytes from murine induced pluripotent stem cells by the inducible overexpression of supporting factors

Autor: Cullmann, Katharina ¹, Jahn, Magdalena ¹, Spindler, Markus ², Schenk, Franziska ¹, Manukjan, Georgi ², Mucci, Adele ³, Steinemann, Doris ⁴, Boller, Klaus ⁵, Schulze, Harald ², Bender, Markus ², Moritz, Thomas ³, Modlich, Ute ^{1, *}

Publikováno v: In Research and Practice in Thrombosis and Haemostasis January 2021 5(1):111-124

A precise and sustainable doxycycline-inducible cell line development platform for reliable mammalian cell engineering with gain-of-function mutations

Autor: Shin, Sung Wook ^a, Min, Honggi ^a, Kim, Jiwon ^a, Lee, Jae Seong ^{a, b, ⁎}

Publikováno v: In Metabolic Engineering November 2024 86:12-28

Forming megakaryocytes from murine-induced pluripotent stem cells by the inducible overexpression of supporting factors

Autor: Adele Mucci, Markus Bender, Ute Modlich, Magdalena Jahn, Harald Schulze, Thomas Moritz, Georgi Manukjan, Franziska Schenk, Doris Steinemann, Markus Spindler, Klaus Boller, Katharina Cullmann

Publikováno v: Research and Practice in Thrombosis and Haemostasis
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 1, Pp 111-124 (2021)
Research and practice in thrombosis and haemostasis, 5(1):111-124

Background Platelets are small anucleate cells that circulate in the blood in a resting state but can be activated by external cues. In case of need, platelets from blood donors can be transfused. As an alternative source, platelets can be produced f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77edcb8111b17f34252611c22b129d76
https://pubmed.ncbi.nlm.nih.gov/33537535

Doxycycline Impairs Mitochondrial Function and Protects Human Glioma Cells from Hypoxia-Induced Cell Death: Implications of Using Tet-Inducible Systems

Autor: Ronellenfitsch, Anna-Luisa Luger, Benedikt Sauer, Nadja I. Lorenz, Anna L. Engel, Yannick Braun, Martin Voss, Patrick N. Harter, Joachim P. Steinbach, Michael W.

Publikováno v: International Journal of Molecular Sciences; Volume 19; Issue 5; Pages: 1504

Inducible gene expression is an important tool in molecular biology research to study protein function. Most frequently, the antibiotic doxycycline is used for regulation of so-called tetracycline (Tet)-inducible systems. In contrast to stable gene o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::2e5f466c4337ddb99864bd88cf592808

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