Výsledky vyhledávání - "Tessy A H Hick"

Akademický článek

Venezuelan equine encephalitis virus non-structural protein 3 dictates superinfection exclusion in mammalian cells

Autor: Tessy A. H. Hick, Taja Zotler, Davita Bosveld, Corinne Geertsema, Monique M. van Oers, Gorben P. Pijlman

Publikováno v: npj Viruses, Vol 2, Iss 1, Pp 1-8 (2024)

Abstract Superinfection exclusion (SIE) prevents secondary infections of already infected cells. Arthritogenic alphaviruses induce SIE via early proteolytical cleavage of replicase precursor by non-structural protein 2 (nsP2). Here, we explore the SI

Externí odkaz: https://doaj.org/article/5849d04b71be4e68a51f2b59c8f05016

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Akademický článek

Packaging of alphavirus-based self-amplifying mRNA yields replication-competent virus through a mechanism of aberrant homologous RNA recombination

Autor: Tessy A. H. Hick, Corinne Geertsema, Reindert Nijland, Gorben P. Pijlman

Publikováno v: mBio, Vol 15, Iss 10 (2024)

ABSTRACT Messenger (m)RNA has taken center stage in vaccine development, gene therapy, and cancer immunotherapy. A next-generation of mRNA is the self-amplifying (sa)mRNA, which induces broad and long-lasting immunity at a lower dose which provides b

Externí odkaz: https://doaj.org/article/229af5e6d6c94a0fbee751905466b5cc

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Akademický článek

Relocation of the attTn7 Transgene Insertion Site in Bacmid DNA Enhances Baculovirus Genome Stability and Recombinant Protein Expression in Insect Cells

Autor: Gorben P. Pijlman, Carissa Grose, Tessy A. H. Hick, Herman E. Breukink, Robin van den Braak, Sandra R. Abbo, Corinne Geertsema, Monique M. van Oers, Dirk E. Martens, Dominic Esposito

Publikováno v: Viruses, Vol 12, Iss 12, p 1448 (2020)

Baculovirus expression vectors are successfully used for the commercial production of complex (glyco)proteins in eukaryotic cells. The genome engineering of single-copy baculovirus infectious clones (bacmids) in E. coli has been valuable in the study

Externí odkaz: https://doaj.org/article/8500244a4580486199fd2a92c3836476

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Real‐time online monitoring of insect cell proliferation and baculovirus infection using digital differential holographic microscopy and machine learning

Autor: Jort J. Altenburg, Maarten Klaverdijk, Damien Cabosart, Laurent Desmecht, Sonja S. Brunekreeft‐Terlouw, Joshua Both, Vivian I. P. Tegelbeckers, Marieke L. P. M. Willekens, Linda van Oosten, Tessy A. H. Hick, Tom M. H. van der Aalst, Gorben P. Pijlman, Monique M. van Oers, René H. Wijffels, Dirk E. Martens

Publikováno v: Biotechnology Progress 39 (2023) 2
Biotechnology Progress, 39(2)

Real-time, detailed online information on cell cultures is essential for understanding modern biopharmaceutical production processes. The determination of key parameters, such as cell density and viability, is usually based on the offline sampling of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34304b0b912c3e36584ba4e1d958d52c
https://doi.org/10.1002/btpr.3318

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Author response for 'Real‐time online monitoring of insect cell proliferation and baculovirus infection using digital differential holographic microscopy and machine learning'

Autor: null Jort J. Altenburg, null Maarten Klaverdijk, null Damien Cabosart, null Laurent Desmecht, null Sonja S. Brunekreeft‐Terlouw, null Joshua Both, null Vivian I. P. Tegelbeckers, null Marieke L. P. M. Willekens, null Linda van Oosten, null Tessy A. H. Hick, null Tom M. H. van der Aalst, null Gorben P. Pijlman, null Monique M. van Oers, null René H. Wijffels, null Dirk E. Martens

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::97a8b22c100f47103a9c0bf413634da9
https://doi.org/10.1002/btpr.3318/v2/response1

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Secreted Trimeric Chikungunya Virus Spikes from Insect Cells: Production, Purification, and Glycosylation Status

Autor: Tessy A. H. Hick, Corinne Geertsema, Maurice G. L. Henquet, Dirk E. Martens, Stefan W. Metz, Gorben P. Pijlman

Publikováno v: Processes, Vol 10, Iss 162, p 162 (2022)
Processes, 10(1)
Processes; Volume 10; Issue 1; Pages: 162
Processes 10 (2022) 1

Chikungunya virus (CHIKV) is a rapidly emerging mosquito-borne virus that causes a severe febrile illness with long-lasting arthralgia in humans. As there is no vaccine to protect humans and limit CHIKV epidemics, the virus continues to be a global p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb0216500ccec442d8d72dc6d57ea08b
https://www.mdpi.com/2227-9717/10/1/162

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Relocation of the attTn7 Transgene Insertion Site in Bacmid DNA Enhances Baculovirus Genome Stability and Recombinant Protein Expression in Insect Cells

Autor: Carissa Grose, Herman E Breukink, Corinne Geertsema, Monique M. van Oers, Tessy A H Hick, Sandra R Abbo, Gorben P. Pijlman, Dominic Esposito, Robin van den Braak, Dirk E. Martens

Publikováno v: Viruses 12 (2020) 12
Viruses
Volume 12
Issue 12
Viruses, 12(12)
Viruses, Vol 12, Iss 1448, p 1448 (2020)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da39b80348c820238e2655ffb8213a9
https://research.wur.nl/en/publications/relocation-of-the-atttn7-transgene-insertion-site-in-bacmid-dna-e

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