Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Tessa N Cressey"'
Autor:
Tessa N Cressey, Afzaal M Shareef, Victoria A Kleiner, Sarah L Noton, Patrick O Byrne, Jason S McLellan, Elke Mühlberger, Rachel Fearns
Publikováno v:
PLoS Pathogens, Vol 18, Iss 6, p e1010451 (2022)
De novo initiation by viral RNA-dependent RNA polymerases often requires a polymerase priming residue, located within a priming loop, to stabilize the initiating NTPs. Polymerase structures from three different non-segmented negative strand RNA virus
Externí odkaz:
https://doaj.org/article/0a13506617e34b1f876b02efa62ecf13
Autor:
Whitney A. Manhart, Jennifer R. Pacheco, Adam J. Hume, Tessa N. Cressey, Laure R. Deflubé, Elke Mühlberger
Publikováno v:
Cell Reports, Vol 24, Iss 10, Pp 2573-2580.e4 (2018)
Summary: Recently, traces of zoonotic viruses have been discovered in bats and other species around the world, but despite repeated attempts, full viral genomes have not been rescued. The absence of critical genetic sequences from these viruses and t
Externí odkaz:
https://doaj.org/article/2d2a22a40624401c8dd05c0962db95cb
Autor:
Tessa N. Cressey, Afzaal M. Shareef, Victoria A. Kleiner, Sarah L. Noton, Patrick O. Byrne, Jason S. McLellan, Elke Mühlberger, Rachel Fearns
De novo initiation by viral RNA-dependent RNA polymerases often requires a polymerase priming residue, located within a priming loop, to stabilize the initiating NTPs. Polymerase structures from three different non-segmented negative strand RNA virus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa55a115356ff51185fdaa1e2b7fa11
https://doi.org/10.1101/2022.03.18.484858
https://doi.org/10.1101/2022.03.18.484858
Autor:
Sarah L. Noton, Junhua Pan, Simon Lattmann, Tiong Han Yeo, Rachel Fearns, Tessa N. Cressey, Xinlei Qian, Abbas El Sahili, Julien Lescar, Huan Jia, Marian Kalocsay, Barbara Ludeke
Publikováno v:
Nature
Respiratory syncytial virus (RSV) and human metapneumovirus (HMPV) cause severe respiratory diseases in infants and elderly adults1. No vaccine or effective antiviral therapy currently exists to control RSV or HMPV infections. During viral genome rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef44955d71cbfe4f2336a624ef0029c6
https://doi.org/10.1038/s41586-019-1759-1
https://doi.org/10.1038/s41586-019-1759-1
Autor:
Elke Mühlberger, Emily V. Nelson, John H. Connor, Laure R. Deflubé, Adam J. Hume, Hideki Ebihara, Jennifer R. Pacheco, Tessa N. Cressey, John B. Ruedas
Publikováno v:
Antiviral Research. 146:21-27
Ebola virus (EBOV) causes a severe disease in humans with the potential for significant international public health consequences. Currently, treatments are limited to experimental vaccines and therapeutics. Therefore, research into prophylaxis and an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::651bd4ff34ae9769b2cc646dedec0d04
https://doi.org/10.1016/j.antiviral.2017.08.005
https://doi.org/10.1016/j.antiviral.2017.08.005
Autor:
Rachel Fearns, Tessa N. Cressey, Laure R. Deflubé, Friederike Feldmann, Elke Mühlberger, Judith Olejnik, Hideki Ebihara, Adam J. Hume, Elaine Haddock
Most nonsegmented negative strand (NNS) RNA virus genomes have complementary 3' and 5' terminal nucleotides because the promoters at the 3' ends of the genomes and antigenomes are almost identical to each other. However, according to published sequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfa76127d0e9f0090b2eb58735c135d0
https://europepmc.org/articles/PMC6486738/
https://europepmc.org/articles/PMC6486738/
Publikováno v:
Journal of Virology. 92
Polyamines and hypusinated eIF5A have been implicated in the replication of diverse viruses; however, defining their roles in supporting virus replication is still under investigation. We have previously reported that Ebola virus (EBOV) requires poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83a97f7d9892bbc21a7356adb87793b3
https://doi.org/10.1128/jvi.01260-18
https://doi.org/10.1128/jvi.01260-18
Autor:
Tessa N. Cressey, Whitney A. Manhart, Laure R. Deflubé, Elke Mühlberger, Adam J. Hume, Jennifer R. Pacheco
Publikováno v:
Cell Reports, Vol 24, Iss 10, Pp 2573-2580.e4 (2018)
Summary: Recently, traces of zoonotic viruses have been discovered in bats and other species around the world, but despite repeated attempts, full viral genomes have not been rescued. The absence of critical genetic sequences from these viruses and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::245163f4a1502c1057f2ad9d6295d2e2
https://pubmed.ncbi.nlm.nih.gov/30184492
https://pubmed.ncbi.nlm.nih.gov/30184492
Publikováno v:
Ebolaviruses ISBN: 9781493971152
In this chapter, we describe the minigenome system for Ebola virus (EBOV), which reconstitutes EBOV polymerase activity in cells and can be used to model viral genome replication and transcription. This protocol comprises all steps including cell cul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53db304ba37eff510d0891185b05b61b
https://doi.org/10.1007/978-1-4939-7116-9_6
https://doi.org/10.1007/978-1-4939-7116-9_6
Publikováno v:
Ebolaviruses ISBN: 9781493971152
In this chapter, we describe the detection of Ebola virus minigenomic mRNA using a nonradioactive Northern hybridization. This protocol comprises all steps beginning with the synthesis of a digoxigenin-labeled riboprobe, harvest of transcribed mRNA f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d4b7d115193276ade68333237998727
https://doi.org/10.1007/978-1-4939-7116-9_11
https://doi.org/10.1007/978-1-4939-7116-9_11