Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Tessa Moses"'
Autor:
Emily J. Johnston, Jess Tallis, Edward Cunningham-Oakes, Tessa Moses, Simon J. Moore, Sarah Hosking, Susan J. Rosser
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Escin is a mixture of over 30 glycosylated triterpenoid (saponin) structures, extracted from the dried fruit of horse chestnuts. Escin is currently used as an anti-inflammatory, and has potential applications in the treatment of arthritis an
Externí odkaz:
https://doaj.org/article/45fe8550be604c0293f915b1a5d6929d
Autor:
Nicole Needham, Iain H. Campbell, Helen Grossi, Ivana Kamenska, Benjamin P. Rigby, Sharon A. Simpson, Emma McIntosh, Pankaj Bahuguna, Ben Meadowcroft, Frances Creasy, Maja Mitchell-Grigorjeva, John Norrie, Gerard Thompson, Melissa C. Gibbs, Ailsa McLellan, Cheryl Fisher, Tessa Moses, Karl Burgess, Rachel Brown, Michael J. Thrippleton, Harry Campbell, Daniel J. Smith
Publikováno v:
BJPsych Open, Vol 9 (2023)
Background Recent evidence from case reports suggests that a ketogenic diet may be effective for bipolar disorder. However, no clinical trials have been conducted to date. Aims To assess the recruitment and feasibility of a ketogenic diet interventi
Externí odkaz:
https://doaj.org/article/6c02bf95d0304e498412e6f76ae2ac78
Autor:
Tessa Moses, Karl Burgess
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
This mini review focuses on the opportunities provided by current and emerging separation techniques for mass spectrometry metabolomics. The purpose of separation technologies in metabolomics is primarily to reduce complexity of the heterogeneous sys
Externí odkaz:
https://doaj.org/article/20f5a1b2d63b439e818e2ea49d8d5e48
Autor:
Zandile Nare, Tessa Moses, Karl Burgess, Achim Schnaufer, Malcolm D. Walkinshaw, Paul A. M. Michels
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Previously, we reported the development of novel small molecules that are potent inhibitors of the glycolytic enzyme phosphofructokinase (PFK) of Trypanosoma brucei and related protists responsible for serious diseases in humans and domestic animals.
Externí odkaz:
https://doaj.org/article/e22a5f125b2a483da392dcbbf91fccdd
Autor:
Henna Myllymäki, Jeanette Astorga Johansson, Estefania Grados Porro, Abigail Elliot, Tessa Moses, Yi Feng
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Metabolic rewiring is a critical hallmark of tumorigenesis and is essential for the development of cancer. Although many key features of metabolic alteration that are crucial for tumor cell survival, proliferation and progression have been identified
Externí odkaz:
https://doaj.org/article/9e344384479a4d48b86a314a5b460f67
Autor:
Maria Carmela Vaccaro, Mariaevelina Alfieri, Nunziatina De Tommasi, Tessa Moses, Alain Goossens, Antonietta Leone
Publikováno v:
Frontiers in Plant Science, Vol 11 (2020)
Abietane diterpenoids (ADs), synthesized in the roots of different Salvia species, such as aethiopinone, 1-oxoaethiopinone, salvipisone, and ferruginol, have a variety of known biological activities. We have shown that aethiopinone has promising cyto
Externí odkaz:
https://doaj.org/article/8735fd080c964d33918be1422ba6b1e4
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0231980 (2020)
Triterpenoids are high-value plant metabolites with numerous applications in medicine, agriculture, food, and home and personal care products. However, plants produce triterpenoids in low abundance, and their complex structures make their chemical sy
Externí odkaz:
https://doaj.org/article/70604f4a8e1a4a6c8e615cd9b57b8561
Autor:
Karel Miettinen, Jacob Pollier, Dieter Buyst, Philipp Arendt, René Csuk, Sven Sommerwerk, Tessa Moses, Jan Mertens, Prashant D Sonawane, Laurens Pauwels, Asaph Aharoni, José Martins, David R. Nelson, Alain Goossens
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Cytochrome P450 family enzymes have an essential role in the creation of triterpenoid diversity in plants. Here, the authors describe triterpenoid synthesis as mediated by CYP716 enzymes in medicinal plant species, and perform phylogenetic analysis t
Externí odkaz:
https://doaj.org/article/66750895d37c4b84bb7e7e2957101e7f
Autor:
Joan Cortada‐Garcia, Jennifer Haggarty, Tessa Moses, Rónán Daly, Susan Alison Arnold, Karl Burgess
Publikováno v:
Cortada-Garcia, J, Haggarty, J, Moses, T, Daly, R, Arnold, S A & Burgess, K 2022, '
untargeted metabolomics monitoring of an escherichia coli succinate fermentation process ', Biotechnology and Bioengineering, vol. 119, no. 10, pp. 2757-2769 . https://doi.org/10.1002/bit.28173
untargeted metabolomics monitoring of an escherichia coli succinate fermentation process ', Biotechnology and Bioengineering, vol. 119, no. 10, pp. 2757-2769 . https://doi.org/10.1002/bit.28173
The real-time monitoring of metabolites (RTMet) is instrumental for the industrial production of biobased fermentation products. This study shows the first application of untargeted on-line metabolomics for the monitoring of undiluted fermentation br
Publikováno v:
Johnston, E J, Moses, T & Rosser, S J 2019, ' The wide-ranging phenotypes of ergosterol biosynthesis mutants, and implications for microbial cell factories ', Yeast, vol. 37, no. 1, pp. 27-44 . https://doi.org/10.1002/yea.3452
Yeast strains have been used extensively as robust microbial cell factories for the production of bulk and fine chemicals, including biofuels (bioethanol), complex pharmaceuticals (antimalarial drug artemisinin and opioid pain killers), flavours, and