Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Tessa M Popay"'
Autor:
Tessa M Popay, Jing Wang, Clare M Adams, Gregory Caleb Howard, Simona G Codreanu, Stacy D Sherrod, John A McLean, Lance R Thomas, Shelly L Lorey, Yuichi J Machida, April M Weissmiller, Christine M Eischen, Qi Liu, William P Tansey
Publikováno v:
eLife, Vol 10 (2021)
The oncoprotein transcription factor MYC is a major driver of malignancy and a highly validated but challenging target for the development of anticancer therapies. Novel strategies to inhibit MYC may come from understanding the co-factors it uses to
Externí odkaz:
https://doaj.org/article/858ae447047d4222bb272f96fbb33a0c
Autor:
Ethan P. Metz, Phillip J. Wilder, Tessa M. Popay, Jing Wang, Qi Liu, Achyuth Kalluchi, M. Jordan Rowley, William P. Tansey, Angie Rizzino
Publikováno v:
Cancers; Volume 14; Issue 8; Pages: 1946
Slowly cycling/infrequently proliferating tumor cells present a clinical challenge due to their ability to evade treatment. Previous studies established that high levels of SOX2 in both fetal and tumor cells restrict cell proliferation and induce a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d9260d2eea2649346ceca4d8f67b4c9
Publikováno v:
Clocks & Sleep, Vol 2, Iss 32, Pp 434-441 (2020)
Clocks & Sleep
Clocks & Sleep; Volume 2; Issue 4; Pages: 434-441
Clocks & Sleep
Clocks & Sleep; Volume 2; Issue 4; Pages: 434-441
General anaesthesia (GA) is implicated as a cause of postoperative sleep disruption and fatigue with part of the disturbance being attributed to a shift of the circadian clock. In this study, Drosophila melanogaster was used as a model to determine h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9772d9a5f0c0903712ecd7d22cca46e3
https://www.mdpi.com/2624-5175/2/4/32
https://www.mdpi.com/2624-5175/2/4/32
Autor:
Tessa M. Popay, Jesse R. Dixon
Publikováno v:
The Journal of biological chemistry. 298(8)
In mammalian organisms, enhancers can regulate transcription from great genomic distances. How enhancers affect distal gene expression has been a major question in the field of gene regulation. One model to explain how enhancers communicate with thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6b3932caf95d3f912835435d7912fd
https://pubmed.ncbi.nlm.nih.gov/35691341
https://pubmed.ncbi.nlm.nih.gov/35691341
Autor:
Jing Wang, April M. Weissmiller, Stacy D. Sherrod, Tessa M. Popay, Simona G. Codreanu, Qi Liu, Lance R. Thomas, John A. McLean, Clare M. Adams, William P. Tansey, Gregory C. Howard, Christine M. Eischen, Shelly L. Lorey, Yuichi J. Machida
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
The oncoprotein transcription factor MYC is a major driver of malignancy and a highly validated but challenging target for the development of anticancer therapies. Novel strategies to inhibit MYC may come from understanding the co-factors it uses to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::934203009b3bc42bf5b991f8353ac55f
https://elifesciences.org/articles/60191
https://elifesciences.org/articles/60191
Autor:
Qi Liu, Stacy D. Sherrod, Simona G. Codreanu, April M. Weissmiller, Shelly L. Lorey, Clare M. Adams, Yuichi J. Machida, John A. McLean, Tessa M. Popay, Jing Wang, Lance R. Thomas, Christine M. Eischen, Gregory C. Howard, William P. Tansey
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b1a4240863cd22f5ecb010e038ad131
https://doi.org/10.7554/elife.60191.sa2
https://doi.org/10.7554/elife.60191.sa2
Autor:
John A. McLean, Lance R. Thomas, Qi Liu, Yuichi J. Machida, Clare M. Adams, Jing Wang, William P. Tansey, Tessa M. Popay, April M. Weissmiller, Stacy D. Sherrod, Shelly L. Lorey, Christine M. Eischen, Simona G. Codreanu
The oncoprotein transcription factor MYC is a major driver of malignancy and a highly-validated but challenging target for development of anti-cancer therapies. Novel strategies to inhibit MYC may come from understanding the co-factors it uses to dri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb780cd8c252b9bf345e69fa6c6286df
https://doi.org/10.1101/2020.06.22.164764
https://doi.org/10.1101/2020.06.22.164764
Autor:
Alissa D. Guarnaccia, Christina E. Wang, April M. Weissmiller, Jing Wang, William P. Tansey, William G. Payne, Kristie L. Rose, Kiana Guerrazzi, J. Grace Shaw, Edward T. Olejniczak, Salisha Hill, Tessa M. Popay, Stephen W. Fesik, Chase M Woodley, Qi Liu, Tyler J. Hansen, Bin Zhao, Shelly L. Lorey
Publikováno v:
Cell reports
SUMMARY The chromatin-associated protein WDR5 is a promising pharmacological target in cancer, with most drug discovery efforts directed against an arginine-binding cavity in WDR5 called the WIN site. Despite a clear expectation that WIN site inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d58182266d573428ca6a794d5618db45
http://europepmc.org/articles/PMC7871196
http://europepmc.org/articles/PMC7871196
Autor:
April M. Weissmiller, Christine M. Eischen, Bethany A. Carboneau, Tessa M. Popay, Victoria H. Ng, Brian C. Grieb, Audra M. Foshage, William P. Tansey, Shelly L. Lorey, Lance R. Thomas, Susan J. Qualls
Publikováno v:
Oncogene
The MYC family of oncogenes encodes a set of three related transcription factors that are overexpressed in many human tumors and contribute to the cancer-related deaths of more than 70,000 Americans every year. MYC proteins drive tumorigenesis by int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb8665292b4449e0b4d33846aeff7504
https://doi.org/10.1038/onc.2015.416
https://doi.org/10.1038/onc.2015.416
Autor:
Tessa M. Popay, Brian I. Hang, Alison Zhong, William P. Tansey, Leah M. Sawyer, Stacey S. Huppert, Kristie L. Rose, Ethan Lee, Leif R. Neitzel, Emily E. Crispi, Laura A. Lee, Victoria H. Ng
Publikováno v:
Journal of cell science. 131(10)
X-linked inhibitor of apoptosis (XIAP) plays an important role in preventing apoptotic cell death. XIAP has been shown to participate in signaling pathways, including Wnt signaling. XIAP regulates Wnt signaling by promoting the monoubiquitylation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e377904c8b2671f07aaad171bed736e
https://pubmed.ncbi.nlm.nih.gov/29678905
https://pubmed.ncbi.nlm.nih.gov/29678905