Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Tessa K, Harris"'
Autor:
Chloe R. Koulouris, Sian E. Gardiner, Tessa K. Harris, Karen T. Elvers, S. Mark Roe, Jason A. Gillespie, Simon E. Ward, Olivera Grubisha, Robert A. Nicholls, John R. Atack, Benjamin D. Bax
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
The catalytic mechanisms of human serine racemase reveal a ligandable pocket near Tyr121 that could be targeted for the development of novel inhibitors.
Externí odkaz:
https://doaj.org/article/08d2829bfb8f4f288b7fb5de272a4d80
Autor:
Alexander V. Nemukhin, Igor V. Alabugin, Colin Berry, D. Dafydd Jones, Tessa K. Harris, Ozan E. Aksakal, Husam Sabah Auhim, Pierre J. Rizkallah, Gabriel dos Passos Gomes, Bella L. Grigorenko, Igor V. Polyakov
Publikováno v:
Chemical Science
Fluorescent proteins (FPs) have revolutionised the life sciences, but the mechanism of chromophore maturation is still not fully understood. Here we show that incorporation of a photo-responsive non-canonical amino acid within the chromophore stalls
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0726bb26e3779588c14247de2edaf31
https://pubmed.ncbi.nlm.nih.gov/34168826
https://pubmed.ncbi.nlm.nih.gov/34168826
Autor:
Chloe R, Koulouris, Sian E, Gardiner, Tessa K, Harris, Karen T, Elvers, S, Mark Roe, Jason A, Gillespie, Simon E, Ward, Olivera, Grubisha, Robert A, Nicholls, John R, Atack, Benjamin D, Bax
Publikováno v:
Communications biology. 5(1)
Human serine racemase (hSR) catalyses racemisation of L-serine to D-serine, the latter of which is a co-agonist of the NMDA subtype of glutamate receptors that are important in synaptic plasticity, learning and memory. In a 'closed' hSR structure con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::82c5a0696958e8707974e024cedc3442
https://pubmed.ncbi.nlm.nih.gov/35410329
https://pubmed.ncbi.nlm.nih.gov/35410329
Autor:
Bella L. Grigorenko, D. Dafydd Jones, Colin Berry, Pierre J. Rizkallah, Alexander V. Nemukhin, Husam Sabah Auhim, Tessa K. Harris, Igor V. Alabugin, Gabriel dos Passos Gomes, Igor V. Polyakov
Fluorescent proteins (FPs) have revolutionised the life sciences but the mechanism of chromophore maturation is still not fully understood. Incorporation of a photo-responsive non-canonical amino acid within the chromophore stalls maturation of Venus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b195c8e0b04ae767bef7a40ec2d1616f
https://doi.org/10.1101/2020.10.13.337386
https://doi.org/10.1101/2020.10.13.337386
