Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Tessa J. Nash"'
Publikováno v:
Veterinary Research, Vol 54, Iss 1, Pp 1-16 (2023)
Abstract Enteroids are miniature self-organising three-dimensional (3D) tissue cultures which replicate much of the complexity of the intestinal epithelium. We recently developed an apical-out leukocyte-containing chicken enteroid model providing a n
Externí odkaz:
https://doaj.org/article/7fcc1f34f5d047b3bdd6cac8761c4fe5
Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Nash et al. develop and characterise multilobulated 3D chicken enteroids from intestinal embryonic villi and adult crypts, which constitute an accessible model of the chicken intestine. This model enables manipulations, such as viral infection, to be
Externí odkaz:
https://doaj.org/article/baf12b80ee7b4780a418e0eb7d08e8a9
Autor:
Colin P Sharp, Beth H Thompson, Tessa J Nash, Ola Diebold, Rute M Pinto, Luke Thorley, Yao-Tang Lin, Samantha Sives, Helen Wise, Sara Clohisey Hendry, Finn Grey, Lonneke Vervelde, Peter Simmonds, Paul Digard, Eleanor R Gaunt
Publikováno v:
Sharp, C P, Thompson, B H, Nash, T J, Diebold, O, Pinto, R M, Thorley, L, Lin, Y-T, Sives, S, Wise, H, Clohisey Hendry, S, Grey, F, Vervelde, L, Simmonds, P, Digard, P & Gaunt, E R 2023, ' CpG dinucleotide enrichment in the influenza A virus genome as a live attenuated vaccine development strategy ', PLoS Pathogens, vol. 19, no. 5, e1011357, pp. 1-34 . https://doi.org/10.1371/journal.ppat.1011357
Synonymous recoding of RNA virus genomes is a promising approach for generating attenuated viruses to use as vaccines. Problematically, recoding typically hinders virus growth, but this may be rectified using CpG dinucleotide enrichment. CpGs are rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f0e8cd1673b92293ecd43eb8616458
https://doi.org/10.1101/2022.04.29.490024
https://doi.org/10.1101/2022.04.29.490024
Autor:
Kate M. Sutton, Helle Niemann, Lonneke Vervelde, Sonja Christian, Lone Hansen, Michael J. McGrew, Tessa J. Nash, Stina Rikke Jensen, Brigid Orr
Publikováno v:
Veterinary Research
Orr, B, Sutton, K, Christian, S, Nash, T, Niemann, H, Hansen, L L, McGrew, M, Jensen, S R & Vervelde, L 2021, ' Novel chicken two-dimensional intestinal model comprising all key epithelial cell types and a mesenchymal sub-layer ', Veterinary Research . https://doi.org/10.1186/s13567-021-01010-z
Veterinary Research, Vol 52, Iss 1, Pp 1-15 (2021)
Orr, B, Sutton, K, Christian, S, Nash, T, Niemann, H, Hansen, L L, McGrew, M, Jensen, S R & Vervelde, L 2021, ' Novel chicken two-dimensional intestinal model comprising all key epithelial cell types and a mesenchymal sub-layer ', Veterinary Research . https://doi.org/10.1186/s13567-021-01010-z
Veterinary Research, Vol 52, Iss 1, Pp 1-15 (2021)
The intestinal epithelium plays a variety of roles including providing an effective physical barrier and innate immune protection against infection. Two-dimensional models of the intestinal epithelium, 2D enteroids, are a valuable resource to investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6ce62c01c4db4ff18dbb7da65228dab
https://pubmed.ncbi.nlm.nih.gov/34819162
https://pubmed.ncbi.nlm.nih.gov/34819162
Autor:
Colin P Sharp, Beth H Thompson, Tessa J Nash, Ola Diebold, Rute M Pinto, Luke Thorley, Yao-Tang Lin, Samantha Sives, Helen Wise, Sara Clohisey Hendry, Finn Grey, Lonneke Vervelde, Peter Simmonds, Paul Digard, Eleanor R Gaunt
Publikováno v:
PLoS Pathogens, Vol 19, Iss 5, p e1011357 (2023)
Synonymous recoding of RNA virus genomes is a promising approach for generating attenuated viruses to use as vaccines. Problematically, recoding typically hinders virus growth, but this may be rectified using CpG dinucleotide enrichment. CpGs are rec
Externí odkaz:
https://doaj.org/article/6c1353e296d148f5a88dfc35be436326