Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Tessa Cigler"'
Autor:
Ying L. Liu, Cecilie Liv Bager, Nicholas Willumsen, Divya Ramchandani, Naomi Kornhauser, Lu Ling, Marta Cobham, Eleni Andreopoulou, Tessa Cigler, Anne Moore, Dayle LaPolla, Veronica Fitzpatrick, Maureen Ward, J. David Warren, Claudia Fischbach, Vivek Mittal, Linda T. Vahdat
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-11 (2021)
Abstract Tetrathiomolybdate (TM) is a novel, copper-depleting compound associated with promising survival in a phase II study of patients with high-risk and triple-negative breast cancer. We sought to elucidate the mechanism of TM by exploring its ef
Externí odkaz:
https://doaj.org/article/37a653a1d4054f088c420dae713f918a
Autor:
Rebecca D. Kehm, John L. Hopper, Esther M. John, Kelly-Anne Phillips, Robert J. MacInnis, Gillian S. Dite, Roger L. Milne, Yuyan Liao, Nur Zeinomar, Julia A. Knight, Melissa C. Southey, Linda Vahdat, Naomi Kornhauser, Tessa Cigler, Wendy K. Chung, Graham G. Giles, Sue-Anne McLachlan, Michael L. Friedlander, Prue C. Weideman, Gord Glendon, Stephanie Nesci, kConFab Investigators, Irene L. Andrulis, Saundra S. Buys, Mary B. Daly, Mary Beth Terry
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-13 (2019)
Abstract Background The use of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) has been associated with reduced breast cancer risk, but it is not known if this association extends to women at familial or genetic risk. We examined the
Externí odkaz:
https://doaj.org/article/5da6d9e843624b0697b2e4db6ae0cbf5
Autor:
Linda Vahdat, Vivek Mittal, Claudia Fischbach, Maureen E. Lane, J. David Warren, Richard Zelkowitz, Elnaz Aljom, Jessica Guillaume-Abraham, Alysia Wiener, Sarah Schneider, Veronica Fitzpatrick, Marta Vallee Cobham, Diana Donovan, Anne Moore, Tessa Cigler, Ellen Chuang, Bo Ri Seo, Eleni Nackos, Sharrell B. Lee, Maureen M. Ward, Naomi Kornhauser, Amy Willis, Nancy Chan
This section contains details of all mixed models utilized in the statistical analyses. The inferential tests performed in this paper necessitates a multiple comparisons adjustment, and details of the adjustment procedure is included in this section
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536d57768d74ce9163e53345aac22105
https://doi.org/10.1158/1078-0432.22464144.v1
https://doi.org/10.1158/1078-0432.22464144.v1
Autor:
Jeffrey N. Weitzel, David R. Gandara, Edward M. Newman, Christopher Ruel, Alice P. Chen, Katherine V. Ferry-Galow, Lily R. Van Tongeren, Josef Herzog, Sharon Sand, Richard Piekarz, Joanne Mortimer, Arti Hurria, Jan H. Beumer, Matthew P. Goetz, Linda T. Vahdat, Timothy J. Moynihan, Helen K. Chew, Rita Nanda, Joseph A. Sparano, Harold A. Harvey, Leah V. Cream, Tessa Cigler, Agustin A. Garcia, Cynthia X. Ma, Banu K. Arun, Paul H. Frankel, George Somlo
Purpose: We aimed to establish the MTD of the poly (ADP-ribose) (PAR) polymerase inhibitor, veliparib, in combination with carboplatin in germline BRCA1- and BRCA2- (BRCA)-associated metastatic breast cancer (MBC), to assess the efficacy of single-ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d88480c7654c250002e3ec3f06fe76
https://doi.org/10.1158/1078-0432.c.6526703
https://doi.org/10.1158/1078-0432.c.6526703
Autor:
Linda Vahdat, Vivek Mittal, Claudia Fischbach, Maureen E. Lane, J. David Warren, Richard Zelkowitz, Elnaz Aljom, Jessica Guillaume-Abraham, Alysia Wiener, Sarah Schneider, Veronica Fitzpatrick, Marta Vallee Cobham, Diana Donovan, Anne Moore, Tessa Cigler, Ellen Chuang, Bo Ri Seo, Eleni Nackos, Sharrell B. Lee, Maureen M. Ward, Naomi Kornhauser, Amy Willis, Nancy Chan
Purpose: Bone marrow–derived progenitor cells, including VEGFR2+ endothelial progenitor cells (EPCs) and copper-dependent pathways, model the tumor microenvironment. We hypothesized that copper depletion using tetrathiomolybdate would reduce EPCs i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00f1b4248fe0bf537c457a3ff11dd98c
https://doi.org/10.1158/1078-0432.c.6525630
https://doi.org/10.1158/1078-0432.c.6525630
Autor:
Jeffrey N. Weitzel, David R. Gandara, Edward M. Newman, Christopher Ruel, Alice P. Chen, Katherine V. Ferry-Galow, Lily R. Van Tongeren, Josef Herzog, Sharon Sand, Richard Piekarz, Joanne Mortimer, Arti Hurria, Jan H. Beumer, Matthew P. Goetz, Linda T. Vahdat, Timothy J. Moynihan, Helen K. Chew, Rita Nanda, Joseph A. Sparano, Harold A. Harvey, Leah V. Cream, Tessa Cigler, Agustin A. Garcia, Cynthia X. Ma, Banu K. Arun, Paul H. Frankel, George Somlo
Veliparib pharmacokinetics with geometric mean* and standard deviation (SD) plasma pharmacokinetic parameters during the phase I combination phase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7652ced183d8631be96f78d1d65a617b
https://doi.org/10.1158/1078-0432.22467641
https://doi.org/10.1158/1078-0432.22467641
Autor:
Jeffrey N. Weitzel, David R. Gandara, Edward M. Newman, Christopher Ruel, Alice P. Chen, Katherine V. Ferry-Galow, Lily R. Van Tongeren, Josef Herzog, Sharon Sand, Richard Piekarz, Joanne Mortimer, Arti Hurria, Jan H. Beumer, Matthew P. Goetz, Linda T. Vahdat, Timothy J. Moynihan, Helen K. Chew, Rita Nanda, Joseph A. Sparano, Harold A. Harvey, Leah V. Cream, Tessa Cigler, Agustin A. Garcia, Cynthia X. Ma, Banu K. Arun, Paul H. Frankel, George Somlo
Best response in phase I* and phase II
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fe1f4e6cbf39c5f6970e122dbb1b735
https://doi.org/10.1158/1078-0432.22467644
https://doi.org/10.1158/1078-0432.22467644
Autor:
Linda Vahdat, Vivek Mittal, Claudia Fischbach, Maureen E. Lane, J. David Warren, Richard Zelkowitz, Elnaz Aljom, Jessica Guillaume-Abraham, Alysia Wiener, Sarah Schneider, Veronica Fitzpatrick, Marta Vallee Cobham, Diana Donovan, Anne Moore, Tessa Cigler, Ellen Chuang, Bo Ri Seo, Eleni Nackos, Sharrell B. Lee, Maureen M. Ward, Naomi Kornhauser, Amy Willis, Nancy Chan
The top panel shows the reaction chemistry of established lysyl oxidase (LOX) activity assay. The bottom panel shows the Amplex Red/HRP-based LOX activity assay that detects LOX activity in vitro.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21814513f3e3461f912d9a3469fe992d
https://doi.org/10.1158/1078-0432.22464147
https://doi.org/10.1158/1078-0432.22464147
Autor:
Linda Vahdat, Vivek Mittal, Claudia Fischbach, Maureen E. Lane, J. David Warren, Richard Zelkowitz, Elnaz Aljom, Jessica Guillaume-Abraham, Alysia Wiener, Sarah Schneider, Veronica Fitzpatrick, Marta Vallee Cobham, Diana Donovan, Anne Moore, Tessa Cigler, Ellen Chuang, Bo Ri Seo, Eleni Nackos, Sharrell B. Lee, Maureen M. Ward, Naomi Kornhauser, Amy Willis, Nancy Chan
This is the demographics table containing brief summary of baseline patient characteristics of patients enrolled on trial.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bdfcd37699e7eb9871437f362a4e97a
https://doi.org/10.1158/1078-0432.22464141
https://doi.org/10.1158/1078-0432.22464141
Autor:
Linda Vahdat, Vivek Mittal, Claudia Fischbach, Maureen E. Lane, J. David Warren, Richard Zelkowitz, Elnaz Aljom, Jessica Guillaume-Abraham, Alysia Wiener, Sarah Schneider, Veronica Fitzpatrick, Marta Vallee Cobham, Diana Donovan, Anne Moore, Tessa Cigler, Ellen Chuang, Bo Ri Seo, Eleni Nackos, Sharrell B. Lee, Maureen M. Ward, Naomi Kornhauser, Amy Willis, Nancy Chan
This is the demographics table containing detailed baseline patient characteristics listed for each of the 75 patients. The data is de-identified.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44297288fe00a52cbd4193be8966031d
https://doi.org/10.1158/1078-0432.22464138
https://doi.org/10.1158/1078-0432.22464138