Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Tessa Brodhag"'
Autor:
Johnson Y.N. Lau, Tessa Brodhag, I. Wayne Cheney, Weidong Zhong, Vicky C. H. Lai, Zhi Hong, Charmaine Lim, Shannon Dempsey, Robert C. Tam
Publikováno v:
Journal of Virology. 76:11148-11154
A direct comparison of the inhibitory effects of alpha, beta, and gamma interferons (IFNs) on replication of a hepatitis C virus subgenomic replicon in a hepatoma cell line revealed similarities in antiviral potency. However, alternate IFN-induced an
Autor:
John Doukas, Xianchang Gong, Andrew McPherson, Suhan Tang, Glenn Noronha, Tessa Brodhag, Daniel L. Lohse, Antonio Boccia, Moorthy S. S. Palanki, Ehab Y. Hanna, Hong Gu, Kathy Barrett, Colleen Gritzen, Shiyin Yee, Hong Zhu, Ningning Zhao, Chi Ching Mak, Elena Dneprovskaia, Ute Splittgerber, Chun P. Chow, Ge Li, Richard E. Fine, Jianguo Cao, Feng Shi, Richard Soll, Xinshan Kang, Steven Hu, Silva Stoughton, Jann Key, Ved P. Pathak, Binqi Zeng, Ahmed A Kousba, John Hood, Boris Klebansky, Joel Renick
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(3)
We describe the identification of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine (3), a potent, orally active Src inhibitor with desirable PK properties, demonstrated activity in human tumor cell l