Nucleoporin Nsp1 surveils the phase state of FG-Nups

Autor: Tegan A. Otto, Tessa Bergsma, Maurice Dekker, Sara N. Mouton, Paola Gallardo, Justina C. Wolters, Anton Steen, Patrick R. Onck, Liesbeth M. Veenhoff

Publikováno v: Cell Reports, Vol 43, Iss 10, Pp 114793- (2024)

Summary: Transport through the nuclear pore complex (NPC) relies on intrinsically disordered FG-nucleoporins (FG-Nups) forming a selective barrier. Away from the NPC, FG-Nups readily form condensates and aggregates, and we address how this behavior i

Externí odkaz: https://doaj.org/article/e1eeaf9c4b9a47fe8aeb7b056514bfad

The chaperone DNAJB6 surveils FG-nucleoporins and is required for interphase nuclear pore complex biogenesis

Autor: E. F. Elsiena Kuiper, Paola Gallardo, Tessa Bergsma, Muriel Mari, Maiara Kolbe Musskopf, Jeroen Kuipers, Ben N. G. Giepmans, Anton Steen, Harm H. Kampinga, Liesbeth M. Veenhoff, Steven Bergink

Publikováno v: Kuiper, E F E, Gallardo, P, Bergsma, T, Mari, M, Kolbe Musskopf, M, Kuipers, J, Giepmans, B N G, Steen, A, Kampinga, H H, Veenhoff, L M & Bergink, S 2022, ' The chaperone DNAJB6 surveils FG-nucleoporins and is required for interphase nuclear pore complex biogenesis ', Nature Cell Biology, vol. 24, no. 11, pp. 1584-1594 . https://doi.org/10.1038/s41556-022-01010-x
Nature Cell Biology, 24, 1584-1594. Nature Publishing Group

Biogenesis of nuclear pore complexes (NPCs) includes the formation of the permeability barrier composed of phenylalanine-glycine-rich nucleoporins (FG-Nups) that regulate the selective passage of biomolecules across the nuclear envelope. The FG-Nups

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80aa6df03fc7932e4af7b7947f490ffb
https://doi.org/10.1038/s41556-022-01010-x

Xanthomonas citri MinC Oscillates from Pole to Pole to Ensure Proper Cell Division and Shape

Autor: André S. G. Lorenzoni, Giordanni C. Dantas, Tessa Bergsma, Henrique Ferreira, Dirk-Jan Scheffers

Publikováno v: Frontiers in Microbiology, Vol 8 (2017)

Xanthomonas citri (Xac) is the causal agent of citrus canker, a disease that affects citrus crops and causes economic impact worldwide. To further characterize cell division in this plant pathogen, we investigated the role of the protein MinC in cell

Externí odkaz: https://doaj.org/article/8263a944bc164b0f90306fa4f2e70eaa

DNA Methylation Clocks and Their Predictive Capacity for Aging Phenotypes and Healthspan

Autor: Ekaterina Rogaeva, Tessa Bergsma

Publikováno v: Neuroscience Insights, Vol 15 (2020)
Neuroscience Insights

The number of age predictors based on DNA methylation (DNAm) profile is rising due to their potential in predicting healthspan and application in age-related illnesses, such as neurodegenerative diseases. The cumulative assessment of DNAm levels at a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b43ccfc6a7a1bbbaaf8f74811a731275
https://doaj.org/article/09177b7993d84d5a8097fe6d3b026f98

Xanthomonas citri MinC Oscillates from Pole to Pole to Ensure Proper Cell Division and Shape

Autor: Dirk Scheffers, Andre S. G. Lorenzoni, Henrique Ferreira, Tessa Bergsma, Giordanni C. Dantas

Publikováno v: Frontiers in Microbiology
Frontiers in Microbiology, 8:1352, 1-12. Frontiers Media S.A.
Frontiers in Microbiology, Vol 8 (2017)
Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46650c612c93bcedc83d46a0ac72a3d6
http://europepmc.org/articles/PMC5515816