Zobrazeno 1 - 10
of 267
pro vyhledávání: '"Tessa, Gordon"'
Autor:
Simeon C. Daeschler, Katelyn J.W. So, Konstantin Feinberg, Marina Manoraj, Jenny Cheung, Jennifer Zhang, Kaveh Mirmoeini, J. Paul Santerre, Tessa Gordon, Gregory H. Borschel
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 1, Pp 291-304 (2025)
Axonal regeneration following surgical nerve repair is slow and often incomplete, resulting in poor functional recovery which sometimes contributes to lifelong disability. Currently, there are no FDA-approved therapies available to promote nerve rege
Externí odkaz:
https://doaj.org/article/2009f2e132494281b004702b62e06aca
Autor:
Masoud Golshadi, Elaine F. Claffey, Jennifer K. Grenier, Andrew Miller, Michael Willand, Michael G. Edwards, Tim P. Moore, Michael Sledziona, Tessa Gordon, Gregory H. Borschel, Jonathan Cheetham
Publikováno v:
npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-13 (2023)
Abstract Effective regeneration after peripheral nerve injury requires macrophage recruitment. We investigated the activation of remodeling pathways within the macrophage population when repair is delayed and identified alteration of key upstream reg
Externí odkaz:
https://doaj.org/article/8a4187182c5d41e5a6c313b2134e85a7
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Diabetes is by far, the most common cause of neuropathy, inducing neurodegeneration of terminal sensory nerve fibers associated with loss of sensation, paresthesia, and persistent pain. Foretinib prevents die-back degeneration in cultured se
Externí odkaz:
https://doaj.org/article/4b8985765d0345cc90bffd191789e728
Autor:
Simeon Christian Daeschler, Marie-Hélène Bourget, Dorsa Derakhshan, Vasudev Sharma, Stoyan Ivaylov Asenov, Tessa Gordon, Julien Cohen-Adad, Gregory Howard Borschel
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract We aimed to develop and validate a deep learning model for automated segmentation and histomorphometry of myelinated peripheral nerve fibers from light microscopic images. A convolutional neural network integrated in the AxonDeepSeg framewor
Externí odkaz:
https://doaj.org/article/0f6324170f344c8c84e66172dee387ed
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 6, Pp 1348-1356 (2022)
Morphological analyses are key outcome assessments for nerve regeneration studies but are historically limited to tissue sections. Novel optical tissue clearing techniques enabling three-dimensional imaging of entire organs at a subcellular resolutio
Externí odkaz:
https://doaj.org/article/80eb15f4486846fb9f02682236376ab8
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2622 (2022)
Whether neuromuscular activity influences the size of motor nerves is controversial. All neuromuscular activity in cat hindlimbs was eliminated by spinal cord isolation (SCI), namely, spinal cord transection above and below the medial gastrocnemius (
Externí odkaz:
https://doaj.org/article/506a32186a924bd1ad58efa6cad13bd4
Autor:
Simeon C. Daeschler, Konstantin Feinberg, Kaveh Mirmoeini, Katelyn Chan, Jennifer Zhang, Tessa Gordon, Gregory H. Borschel
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 10, Iss 1S, Pp 8-9 (2022)
Externí odkaz:
https://doaj.org/article/3f977fd6ad264956b1afe7dc91af8c75
Autor:
Seyed Kaveh Mirmoeini, MD, MSc, Konstantin Feinberg, PhD, Kiana Tajdaran, MAS, MD, Jennifer Zhang, MD, PhD, Tessa Gordon, PhD, Gregory H. Borschel, MD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 9, Iss 10S, Pp 106-107 (2021)
Externí odkaz:
https://doaj.org/article/52a92116fffa4e15b05438ff76adb0d8
Autor:
Laura J Wagstaff, Jose A Gomez-Sanchez, Shaline V Fazal, Georg W Otto, Alastair M Kilpatrick, Kirolos Michael, Liam YN Wong, Ki H Ma, Mark Turmaine, John Svaren, Tessa Gordon, Peter Arthur-Farraj, Sergio Velasco-Aviles, Hugo Cabedo, Cristina Benito, Rhona Mirsky, Kristjan R Jessen
Publikováno v:
eLife, Vol 10 (2021)
After nerve injury, myelin and Remak Schwann cells reprogram to repair cells specialized for regeneration. Normally providing strong regenerative support, these cells fail in aging animals, and during chronic denervation that results from slow axon g
Externí odkaz:
https://doaj.org/article/71cf5cebbc4d40f8b6b3a29c0b196abc
Autor:
Kiana Tajdaran, MD, MASc, Konstantin Feinberg, PhD, Seyed K. Mirmoeini, MD, MASc, Jennifer Zhang, MD, PhD, Tessa Gordon, PhD, Asim Ali, MD, Gregory Borschel, MD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 10, Iss 6S, Pp 47-47 (2022)
Externí odkaz:
https://doaj.org/article/960ffeac083a4caf8672e220ea8a9122