Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Tess Whitwam"'
Publikováno v:
Cell Reports, Vol 16, Iss 4, Pp 928-938 (2016)
A longstanding mystery has been the absence of cytoplasmic intermediate filaments (IFs) from Drosophila despite their importance in other organisms. In the course of characterizing the in vivo expression and functions of Drosophila Tropomyosin (Tm) i
Externí odkaz:
https://doaj.org/article/f01f77f7938f4e76821b8ea2663adaf0
Autor:
Swetha E Murthy, Adrienne E Dubin, Tess Whitwam, Sebastian Jojoa-Cruz, Stuart M Cahalan, Seyed Ali Reza Mousavi, Andrew B Ward, Ardem Patapoutian
Publikováno v:
eLife, Vol 7 (2018)
Mechanically activated (MA) ion channels convert physical forces into electrical signals, and are essential for eukaryotic physiology. Despite their importance, few bona-fide MA channels have been described in plants and animals. Here, we show that v
Externí odkaz:
https://doaj.org/article/21be4628362d442387f027bc248cfc59
Autor:
Jennifer M Kefauver, Kei Saotome, Adrienne E Dubin, Jesper Pallesen, Christopher A Cottrell, Stuart M Cahalan, Zhaozhu Qiu, Gunhee Hong, Christopher S Crowley, Tess Whitwam, Wen-Hsin Lee, Andrew B Ward, Ardem Patapoutian
Publikováno v:
eLife, Vol 7 (2018)
SWELL1 (LRRC8A) is the only essential subunit of the Volume Regulated Anion Channel (VRAC), which regulates cellular volume homeostasis and is activated by hypotonic solutions. SWELL1, together with four other LRRC8 family members, potentially forms
Externí odkaz:
https://doaj.org/article/e5adeb3c861446b49e6c931bba50f887
Autor:
Kei Saotome, Swetha E. Murthy, Jennifer M. Kefauver, Tess Whitwam, Ardem Patapoutian, Andrew B. Ward
Publikováno v:
Nature. 607:E10-E10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b0002388e97ea8c90527cae9246efdd
https://doi.org/10.1038/s41586-022-04976-8
https://doi.org/10.1038/s41586-022-04976-8
Autor:
Benyam Kinde, Alexander W. Greben, Emmy Li, Hume Stroud, Andrew Silberfeld, Lisa D. Boxer, Tess Whitwam, Eric C. Griffith, Boyan B. Bonev, Michael E. Greenberg, Marty G. Yang, William Renthal
Publikováno v:
Mol. Cell 77, 294-309.e9 (2020)
Mol Cell
Mol Cell
Mutations in the methyl-DNA-binding repressor protein MeCP2 cause the devastating neurodevelopmental disorder Rett syndrome. It has been challenging to understand how MeCP2 regulates transcription because MeCP2 binds broadly across the genome, and Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3274932aec2be562569c83f8776db003
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=57858
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=57858
Autor:
Ardem Patapoutian, Akemi Kanie, Sanjeev S. Ranade, Tess Whitwam, Mark L. Kahn, Toshihiko Fujimori, Daniel T. Sweet, Keiko Nonomura, Viktor Lukacs, Lauren M. Goddard
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance PIEZOs are mechanically activated cation channels. Recently, loss-of-function mutations of human PIEZO1 were found among patients with familial lymphedema, suggesting a requirement of PIEZO1 in the lymphatic system. In this paper, utiliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8e94b3c1140bec0d011e15065221398
http://europepmc.org/articles/PMC6294938
http://europepmc.org/articles/PMC6294938
Autor:
Jennifer M. Kefauver, Tess Whitwam, Kei Saotome, Ardem Patapoutian, Swetha E. Murthy, Andrew B. Ward
Publikováno v:
Nature. 554:481-486
Piezo1 and Piezo2 are mechanically activated ion channels that mediate touch perception, proprioception and vascular development. Piezo proteins are distinct from other ion channels and their structure remains poorly defined, which impedes detailed s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad67f1dc98189ba948ab9d59832b66b9
https://doi.org/10.1038/nature25453
https://doi.org/10.1038/nature25453
Publikováno v:
Cell reports, vol 16, iss 4
Cell Reports, Vol 16, Iss 4, Pp 928-938 (2016)
Cell Reports, Vol 16, Iss 4, Pp 928-938 (2016)
A longstanding mystery has been the absence ofcytoplasmic intermediate filaments (IFs) from Drosophila despite their importance in other organisms. In the course of characterizing the invivo expression and functions of Drosophila Tropomyosin (Tm) iso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1794c3700502a9145a5460e514da7c29
Autor:
Adrienne E. Dubin, Tess Whitwam, Sebastian Jojoa-Cruz, Stuart M. Cahalan, Swetha E. Murthy, Ardem Patapoutian, Andrew B. Ward, Seyed Ali Reza Mousavi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18731611c18f72d527ab8f108ac236a6
https://doi.org/10.7554/elife.41844.019
https://doi.org/10.7554/elife.41844.019
Autor:
Andrew B. Ward, Tess Whitwam, Sebastian Jojoa Cruz, Ardem Patapoutian, Adrienne E. Dubin, Swetha E. Murthy, Seyed Ali Reza Mousavi, Stuart M. Cahalan
Publikováno v:
eLife
eLife, Vol 7 (2018)
eLife, Vol 7 (2018)
IntroductionMechanotransduction, the conversion of mechanical cues into biochemical signals, is crucial for many biological processes in plants and animals1,2. In mammals, some mechanosensory processes such as touch sensation and vascular development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f5f1fb9bb9fba3b1fe173823352d07d
https://doi.org/10.1101/408732
https://doi.org/10.1101/408732