Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Tess, Lamer"'
Autor:
Pu Chen, Tayla J. Van Oers, Elena Arutyunova, Conrad Fischer, Chaoxiang Wang, Tess Lamer, Marco J. van Belkum, Howard S. Young, John C. Vederas, M. Joanne Lemieux
Publikováno v:
JACS Au, Vol 4, Iss 8, Pp 3217-3227 (2024)
Externí odkaz:
https://doaj.org/article/43087000c76649d4af843aa50a0189fd
Autor:
Elena Arutyunova, Alexandr Belovodskiy, Pu Chen, Muhammad Bashir Khan, Michael Joyce, Holly Saffran, Jimmy Lu, Zoe Turner, Bing Bai, Tess Lamer, Howard S. Young, John C. Vederas, D. Lorne Tyrrell, M. Joanne Lemieux, James A. Nieman
Publikováno v:
ACS Bio & Med Chem Au, Vol 3, Iss 6, Pp 528-541 (2023)
Externí odkaz:
https://doaj.org/article/b8e37dea5f004761a5ac48cc97ba66e2
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 1 (2024)
ABSTRACT Lactococcin A is a bacteriocin from Lactococcus lactis that permeabilizes the membrane of sensitive lactococcal cells and requires the presence of the membrane-bound components IIC and IID of the mannose phosphotransferase system (man-PTS).
Externí odkaz:
https://doaj.org/article/688b2c9450594ff985aef584d1521926
Autor:
Tess Lamer, John C. Vederas
Publikováno v:
BMC Biotechnology, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Some peptides are targets for degradation when heterologously expressed as fusion proteins in E. coli, which can limit yields after isolation and purification. We recently reported that peptide degradation may be prevented by prod
Externí odkaz:
https://doaj.org/article/bdc4ab2fb6994f3f830dfdb61bda1536
Autor:
Wayne Vuong, Muhammad Bashir Khan, Conrad Fischer, Elena Arutyunova, Tess Lamer, Justin Shields, Holly A. Saffran, Ryan T. McKay, Marco J. van Belkum, Michael A. Joyce, Howard S. Young, D. Lorne Tyrrell, John C. Vederas, M. Joanne Lemieux
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Coronavirus main protease is essential for viral polyprotein processing and replication. Here Vuong et al. report efficient inhibition of SARS-CoV-2 replication by the dipeptide-based protease inhibitor GC376 and its parent GC373, which were original
Externí odkaz:
https://doaj.org/article/3c902c5ef40f40398c856f91dffa7d74
Autor:
Jimmy Lu, Sizhu Amelia Chen, Muhammad Bashir Khan, Raelynn Brassard, Elena Arutyunova, Tess Lamer, Wayne Vuong, Conrad Fischer, Howard S. Young, John C. Vederas, M. Joanne Lemieux
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Coronaviruses infect a variety of hosts in the animal kingdom, and while each virus is taxonomically different, they all infect their host via the same mechanism. The coronavirus main protease (Mpro, also called 3CLpro), is an attractive target for d
Externí odkaz:
https://doaj.org/article/10bc0488429546de95a3dbd8df1e6b43
Autor:
Sizhu Amelia Chen, Elena Arutyunova, Jimmy Lu, Muhammad Bashir Khan, Wioletta Rut, Mikolaj Zmudzinski, Shima Shahbaz, Jegan Iyyathurai, Eman W. Moussa, Zoe Turner, Bing Bai, Tess Lamer, James A. Nieman, John C. Vederas, Olivier Julien, Marcin Drag, Shokrollah Elahi, Howard S. Young, M. Joanne Lemieux
Publikováno v:
ACS Central Science. 9:696-708
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06bc781507dacd5fb23130306731addf
https://doi.org/10.1021/acscentsci.3c00054
https://doi.org/10.1021/acscentsci.3c00054
Autor:
Sizhu Amelia Chen, Elena Arutyunova, Jimmy Lu, Muhammad Bashir Khan, Wioletta Rut, Mikolaj Zmudzinski, Shima Shahbaz, Jegan Iyyathurai, Eman Moussa, Zoe Turner, Bing Bai, Tess Lamer, James A. Nieman, John C. Vederas, Olivier Julien, Marcin Drag, Shokrollah Elahi, Howard S. Young, M. Joanne Lemieux
Main protease of SARS-CoV-2 (Mpro) is the most promising drug target against coronaviruses due to its essential role in virus replication. With newly emerging variants there is a concern that mutations in Mpromay alter structural and functional prope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ee9208612c8234925406e453eff6a5a
https://doi.org/10.1101/2023.01.28.525917
https://doi.org/10.1101/2023.01.28.525917
Autor:
Wayne Vuong, Muhammad Bashir Khan, Conrad Fischer, Elena Arutyunova, Tess Lamer, Justin Shields, Holly A. Saffran, Ryan T. McKay, Marco J. van Belkum, Michael A. Joyce, Howard S. Young, D. Lorne Tyrrell, John C. Vederas, M. Joanne Lemieux
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/dac69d533a794d48837c50ee74ddec00
Publikováno v:
Current protocolsLiterature CitedInternet Resources. 2(10)
Heterologous expression in Escherichia coli is a commonly used method to produce ribosomally synthesized peptides for further study. This generally requires expression of the target protein with an affinity fusion tag, followed by isolation of the fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38403a4ce74bd08b357db0ec448699b2
https://pubmed.ncbi.nlm.nih.gov/36222539
https://pubmed.ncbi.nlm.nih.gov/36222539