Zobrazeno 1 - 10
of 235
pro vyhledávání: '"Teslovich, Tanya M."'
Publikováno v:
Statistical Science 2009, Vol. 24, No. 4, 530-546
Copy number variants (CNVs) account for more polymorphic base pairs in the human genome than do single nucleotide polymorphisms (SNPs). CNVs encompass genes as well as noncoding DNA, making these polymorphisms good candidates for functional variation
Externí odkaz:
http://arxiv.org/abs/1010.5040
Autor:
Kwong, Alan, Zawistowski, Matthew, Fritsche, Lars G, Zhan, Xiaowei, Bragg-Gresham, Jennifer, Branham, Kari E, Advani, Jayshree, Othman, Mohammad, Ratnapriya, Rinki, Teslovich, Tanya M, Stambolian, Dwight, Chew, Emily Y, Abecasis, Gonçalo R, Swaroop, Anand
Publikováno v:
Human Molecular Genetics; 2/15/2024, Vol. 33 Issue 4, p374-385, 12p
Autor:
Jun, Goo, Manning, Alisa, Almeida, Marcio, Zawistowski, Matthew, Wood, Andrew R., Teslovich, Tanya M., Fuchsberger, Christian, Feng, Shuang, Cingolani, Pablo, Gaulton, Kyle J., Dyer, Thomas, Blackwell, Thomas W., Chen, Han, Chines, Peter S., Choi, Sungkyoung, Churchhouse, Claire, Fontanillas, Pierre, King, Ryan, Lee, SungYoung, Lincoln, Stephen E., Trubetskoy, Vasily, DePristo, Mark, Fingerlin, Tasha, Grossman, Robert, Grundstad, Jason, Heath, Alison, Kim, Jayoun, Kim, Young Jin, Laramie, Jason, Lee, Jaehoon, Li, Heng, Liu, Xuanyao, Livne, Oren, Locke, Adam E., Maller, Julian, Mazur, Alexander, Morris, Andrew P., Pollin, Toni I., Ragona, Derek, Reich, David, Rivas, Manuel A., Scott, Laura J., Sim, Xueling, Tearle, Rick G., Teo, Yik Ying, Williams, Amy L., Zöllner, Sebastian, Curran, Joanne E., Peralta, Juan, Akolkar, Beena, Bell, Graeme I., Burtt, Noël P., Cox, Nancy J., Florez, Jose C., Hanis, Craig L., McKeon, Catherine, Mohlke, Karen L., Seielstad, Mark, Wilson, James G., Atzmon, Gil, Below, Jennifer E., Dupuis, Josée, Nicolae, Dan L., Lehman, Donna, Park, Taesung, Won, Sungho, Sladek, Robert, Altshuler, David, McCarthy, Mark I., Duggirala, Ravindranath, Boehnke, Michael, Frayling, Timothy M., Abecasis, Gonçalo R., Blangero, John
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2018 Jan 01. 115(2), 379-384.
Externí odkaz:
https://www.jstor.org/stable/26506276
Akademický článek
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Autor:
Praveen, Kavita, Patel, Gaurang C., Gurski, Lauren, Ayer, Ariane H., Persaud, Trikaladarshi, Still, Matthew D., Miloscio, Lawrence, Van Zyl, Tavé, Di Gioia, Silvio Alessandro, Brumpton, Ben, Krebs, Kristi, Åsvold, Bjørn Olav, Chen, Esteban, Chavali, Venkata R. M., Fury, Wen, Gudiseva, Harini V., Hyde, Sarah, Jorgenson, Eric, Lefebvre, Stephanie, Li, Dadong, Li, Alexander, Mclninch, James, Patel, Brijeshkumar, Rabinowitz, Jeremy S., Salowe, Rebecca, Schurmann, Claudia, Seidelin, Anne-Sofie, Stahl, Eli, Sun, Dylan, Teslovich, Tanya M., Tybjærg-Hansen, Anne, Willer, Cristen, Waldron, Scott, Walley, Sabrina, Yang, Hua, Zaveri, Sarthak, Hu, Ying, Hveem, Kristian, Melander, Olle, Milani, Lili, Stender, Stefan, O'Brien, Joan M., Jones, Marcus B., Abecasis, Gonçalo R., Cantor, Michael N., Weyne, Jonathan, Karalis, Katia, Economides, Aris, Della Gatta, Giusy, Ferreira, Manuel A., Yancopoulos, George D., Baras, Aris, Romano, Carmelo, Coppola, Giovanni
Publikováno v:
Praveen, K, Patel, G C, Gurski, L, Ayer, A H, Persaud, T, Still, M D, Miloscio, L, Van Zyl, T, Di Gioia, S A, Brumpton, B, Krebs, K, Åsvold, B O, Chen, E, Chavali, V R M, Fury, W, Gudiseva, H V, Hyde, S, Jorgenson, E, Lefebvre, S, Li, D, Li, A, Mclninch, J, Patel, B, Rabinowitz, J S, Salowe, R, Schurmann, C, Seidelin, A-S, Stahl, E, Sun, D, Teslovich, T M, Tybjærg-Hansen, A, Willer, C, Waldron, S, Walley, S, Yang, H, Zaveri, S, Hu, Y, Hveem, K, Melander, O, Milani, L, Stender, S, O'Brien, J M, Jones, M B, Abecasis, G R, Cantor, M N, Weyne, J, Karalis, K, Economides, A, Della Gatta, G, Ferreira, M A, Yancopoulos, G D, Baras, A, Romano, C, Coppola, G, Regeneron Genetics Center, GHS-RGC DiscovEHR Collaboration & Estonian Biobank Research Team 2022, ' ANGPTL7, a therapeutic target for increased intraocular pressure and glaucoma ', Communications Biology, vol. 5, 1051 . https://doi.org/10.1038/s42003-022-03932-6
Communications Biology
Communications Biology
Glaucoma is a leading cause of blindness. Current glaucoma medications work by lowering intraocular pressure (IOP), a risk factor for glaucoma, but most treatments do not directly target the pathological changes leading to increased IOP, which can ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4af26250e650870007ff7345e6173bb1
https://curis.ku.dk/portal/da/publications/angptl7-a-therapeutic-target-for-increased-intraocular-pressure-and-glaucoma(fa70bc4b-e5a5-4761-80b1-c0f993b851f8).html
https://curis.ku.dk/portal/da/publications/angptl7-a-therapeutic-target-for-increased-intraocular-pressure-and-glaucoma(fa70bc4b-e5a5-4761-80b1-c0f993b851f8).html
Publikováno v:
Statistical Science, 2009 Nov 01. 24(4), 530-546.
Externí odkaz:
https://www.jstor.org/stable/25681330
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Blangero, John1, Teslovich, Tanya M.2, Xueling Sim2, Almeida, Marcio A.1, Goo Jun2,3, Dyer, Thomas D.1, Johnson, Matthew1, Peralta, Juan M.1, Manning, Alisa4, Wood, Andrew R.5, Fuchsberger, Christian2, Kent Jr, Jack W.6, Aguilar, David A.7, Below, Jennifer E.3, Farook, Vidya S.1, Arya, Rector1, Fowler, Sharon8, Blackwell, Tom W.2, Puppala, Sobha6, Kumar, Satish1
Publikováno v:
BMC Proceedings. 10/18/2016, Vol. 10, p71-77. 7p. 2 Charts.
Autor:
Flannick, Jason, Mercader, Josep M, Fuchsberger, Christian, Udler, Miriam S, Mahajan, Anubha, Wessel, Jennifer, Teslovich, Tanya M, Caulkins, Lizz, Koesterer, Ryan, Barajas-Olmos, Francisco, Blackwell, Thomas W, Boerwinkle, Eric, Brody, Jennifer A, Centeno-Cruz, Federico, Chen, Ling, Chen, Siying, Contreras-Cubas, Cecilia, Córdova, Emilio, Correa, Adolfo, Cortes, Maria, DeFronzo, Ralph A, Dolan, Lawrence, Drews, Kimberly L, Elliott, Amanda, Floyd, James S, Gabriel, Stacey, Garay-Sevilla, Maria Eugenia, García-Ortiz, Humberto, Gross, Myron, Han, Sohee, Heard-Costa, Nancy L, Jackson, Anne U, Jørgensen, Marit E, Kang, Hyun Min, Kelsey, Megan, Kim, Bong-Jo, Koistinen, Heikki A, Kuusisto, Johanna, Leader, Joseph B, Linneberg, Allan, Liu, Ching-Ti, Liu, Jianjun, Lyssenko, Valeriya, Manning, Alisa K, Marcketta, Anthony, Malacara-Hernandez, Juan Manuel, Martínez-Hernández, Angélica, Matsuo, Karen, Mayer-Davis, Elizabeth, Mendoza-Caamal, Elvia, Mohlke, Karen L, Morrison, Alanna C, Ndungu, Anne, Ng, Maggie CY, O'Dushlaine, Colm, Payne, Anthony J, Pihoker, Catherine, Broad Genomics Platform, Post, Wendy S, Preuss, Michael, Psaty, Bruce M, Vasan, Ramachandran S, Rayner, N William, Reiner, Alexander P, Revilla-Monsalve, Cristina, Robertson, Neil R, Santoro, Nicola, Schurmann, Claudia, So, Wing Yee, Soberón, Xavier, Stringham, Heather M, Strom, Tim M, Tam, Claudia HT, Thameem, Farook, Tomlinson, Brian, Torres, Jason M, Tracy, Russell P, van Dam, Rob M, Vujkovic, Marijana, Wang, Shuai, Welch, Ryan P, Witte, Daniel R, Wong, Tien-Yin, Atzmon, Gil, Barzilai, Nir, Blangero, John, Bonnycastle, Lori L, Bowden, Donald W, Chambers, John C, Chan, Edmund, Cheng, Ching-Yu, Cho, Yoon Shin, Collins, Francis S, de Vries, Paul S, Duggirala, Ravindranath, Glaser, Benjamin, Gonzalez, Clicerio, Gonzalez, Ma Elena, Groop, Leif, Kooner, Jaspal Singh
Publikováno v:
Nature, vol 570, iss 7759
Protein-coding genetic variants that strongly affect disease risk can yield relevant clues to disease pathogenesis. Here we report exome-sequencing analyses of 20,791individuals with type 2 diabetes (T2D) and 24,440non-diabetic control participants f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::422a00f92ff1ca8af073bfd4a26ef831
https://escholarship.org/uc/item/0zj719b5
https://escholarship.org/uc/item/0zj719b5
Autor:
Klarin, Derek, Damrauer, Scott M, Cho, Kelly, Sun, Yan V, Teslovich, Tanya M, Honerlaw, Jacqueline, Gagnon, David R, DuVall, Scott L, Li, Jin, Peloso, Gina M, Chaffin, Mark, Small, Aeron M, Huang, Jie, Tang, Hua, Lynch, Julie A, Ho, Yuk-Lam, Liu, Dajiang J, Emdin, Connor A, Li, Alexander H, Huffman, Jennifer E, Lee, Jennifer S, Natarajan, Pradeep, Chowdhury, Rajiv, Saleheen, Danish, Vujkovic, Marijana, Baras, Aris, Pyarajan, Saiju, Di Angelantonio, Emanuele, Neale, Benjamin M, Naheed, Aliya, Khera, Amit V, Danesh, John, Chang, Kyong-Mi, Abecasis, Gonçalo, Willer, Cristen, Dewey, Frederick E, Carey, David J, Global Lipids Genetics Consortium, Myocardial Infarction Genetics (MIGen) Consortium, Geisinger-Regeneron DiscovEHR Collaboration, VA Million Veteran Program, Concato, John, Gaziano, J Michael, O'Donnell, Christopher J, Tsao, Philip S, Kathiresan, Sekar, Rader, Daniel J, Wilson, Peter WF, Assimes, Themistocles L
The Million Veteran Program (MVP) was established in 2011 as a national research initiative to determine how genetic variation influences the health of US military veterans. Here we genotyped 312,571 MVP participants using a custom biobank array and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______109::3c432d60806348cc5e859ff78d9e2ab0
https://www.repository.cam.ac.uk/handle/1810/279839
https://www.repository.cam.ac.uk/handle/1810/279839