Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Tesfaye M Baye"'
Autor:
Lisa J Martin, Jayanta Gupta, Soma S S K Jyothula, Melinda Butsch Kovacic, Jocelyn M Biagini Myers, Tia L Patterson, Mark B Ericksen, Hua He, Aaron M Gibson, Tesfaye M Baye, Sushil Amirisetty, Anna M Tsoras, Youbao Sha, N Tony Eissa, Gurjit K Khurana Hershey
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e33454 (2012)
Rationale and objectiveAutophagy is a cellular process directed at eliminating or recycling cellular proteins. Recently, the autophagy pathway has been implicated in immune dysfunction, the pathogenesis of inflammatory disorders, and response to vira
Externí odkaz:
https://doaj.org/article/387c3faf46704aaca8344c0be9ea39da
Autor:
Tesfaye M Baye, Melinda Butsch Kovacic, Jocelyn M Biagini Myers, Lisa J Martin, Mark Lindsey, Tia L Patterson, Hua He, Mark B Ericksen, Jayanta Gupta, Anna M Tsoras, Andrew Lindsley, Marc E Rothenberg, Marsha Wills-Karp, N Tony Eissa, Larry Borish, Gurjit K Khurana Hershey
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16522 (2011)
BackgroundCandidate gene case-control studies have identified several single nucleotide polymorphisms (SNPs) that are associated with asthma susceptibility. Most of these studies have been restricted to evaluations of specific SNPs within a single ge
Externí odkaz:
https://doaj.org/article/ccb79b07379a45bcbabd5246bbd0edd7
Autor:
Melinda Butsch Kovacic, Jocelyn M Biagini Myers, Ning Wang, Lisa J Martin, Mark Lindsey, Mark B Ericksen, Hua He, Tia L Patterson, Tesfaye M Baye, Dara Torgerson, Lindsey A Roth, Jayanta Gupta, Umasundari Sivaprasad, Aaron M Gibson, Anna M Tsoras, Donglei Hu, Celeste Eng, Rocío Chapela, José R Rodríguez-Santana, William Rodríguez-Cintrón, Pedro C Avila, Kenneth Beckman, Max A Seibold, Chris Gignoux, Salma M Musaad, Weiguo Chen, Esteban González Burchard, Gurjit K Khurana Hershey
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23714 (2011)
Asthma is a chronic inflammatory disease with a strong genetic predisposition. A major challenge for candidate gene association studies in asthma is the selection of biologically relevant genes.Using epithelial RNA expression arrays, HapMap allele fr
Externí odkaz:
https://doaj.org/article/5f4cc418e1864f3d8f3a32d8a027af35
Autor:
Naoyuki Hirata, Zeljko J. Bosnjak, Tesfaye M. Baye, Molly Pellitteri-Hahn, Michael Olivier, Martin Bienengraeber
Publikováno v:
Physiological Genomics. 45:163-170
Changes in mitochondrial bioenergetics have been proposed to be critical for triggering and effecting anesthetic-induced preconditioning (APC) against cardiac ischemia and reperfusion injury. The objective of this study was to analyze changes in mito
Publikováno v:
Pharmacogenomics. 13:579-594
Skeletal muscle toxicity is the primary adverse effect of statins. In this review, we summarize current knowledge regarding the genetic and nongenetic determinants of risk for statin induced myopathy. Many genetic factors were initially identified th
Autor:
Russell A. Wilke, Tesfaye M. Baye
Publikováno v:
The Pharmacogenomics Journal. 10:465-477
There is great interest in characterizing the genetic architecture underlying drug response. For many drugs, gene-based dosing models explain a considerable amount of the overall variation in treatment outcome. As such, prescription drug labels are i
Publikováno v:
Journal of Allergy and Clinical Immunology. 126:425-436
Completion of the human genome project and rapid progress in genetics and bioinformatics have enabled the development of large public databases, which include genetic and genomic data linked to clinical health data. With the massive amount of informa
Autor:
Samer Gawrieh, Joanne E. Curran, Bassem Makladi, Deborah A. Andris, John Blangero, Ahmed H. Kissebah, Richard A. Komorowski, Regina Cole, James R. Wallace, Tesfaye M. Baye, Thomas D. Dyer, David E. Kleiner, Jac Charlesworth, Michael Charlton, Michael Olivier, Russell A. Wilke, Melanie A. Carless
Publikováno v:
Obes Surg
BACKGROUND: Genetic factors alter the risk for nonalcoholic fatty liver disease (NAFLD). We sought to identify NAFLD-associated genes and elucidate gene networks and pathways involved in the pathogenesis of NAFLD. METHODS: Quantitative global hepatic
Autor:
Yi Zhang, Ann DeLaForest, Gabriele E. Sonnenberg, Erin MacKinney, Russell A. Wilke, Jennifer Gunnell, Jack Littrell, Cecilia J. Hillard, Ahmed H. Kissebah, Tesfaye M. Baye, Michael Olivier
Publikováno v:
Pharmacogenomics. 10:1929-1939
A more thorough understanding of the genetic architecture underlying obesity-related lipid disorders could someday facilitate cardiometabolic risk reduction through early clinical intervention based upon improved characterization of individual risk.
Publikováno v:
Personalized Medicine. 6:623-641
Aims: Geography-based genetic differentials operating on entire biochemical pathways may reflect different adaptive evolutionary processes that separated populations may have undergone. They may also influence treatment outcome for a variety of drugs