Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Tesfai Emahazion"'
Autor:
Lars Feuk, Magnus Jobs, David Fredman, David St Clair, Anthony J. Brookes, Tesfai Emahazion, Jonathan A. Prince, Sarah L. Sawyer
Publikováno v:
Trends in Genetics. 17:407-413
Genetic linkage and association analyses are two distinct approaches to understanding the genetic etiology of complex disease. Association analysis has become particularly popular in recent times, but the true utility of the strategy remains uncertai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::867ae8e3324286416869c93784852f2c
https://doi.org/10.1016/s0168-9525(01)02342-3
https://doi.org/10.1016/s0168-9525(01)02342-3
Autor:
Lars Feuk, Jonathan A. Prince, W. Mathias Howell, Magnus Jobs, Kaj Blennow, Tesfai Emahazion, Anthony J. Brookes
Publikováno v:
Genome Research. 11:152-162
We recently introduced a generic single nucleotide polymorphism (SNP) genotyping method, termed DASH (dynamic allele-specific hybridization), which entails dynamic tracking of probe (oligonucleotide) to target (PCR product) hybridization as reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bcec4f293d8c673f7d87e6af4adc052
https://doi.org/10.1101/gr.150201
https://doi.org/10.1101/gr.150201
Autor:
N Andreasen, Lars Rymo, Katarina Nägga, Jan Marcusson, Björn Regland, Kaj Blennow, A Jansson, C Hesse, Lennart Minthon, Anders Wallin, Hasse Olofsson, Anthony J. Brookes, Anne Ricksten, Nenad Bogdanovic, Jonathan A. Prince, Stellan Båtsman, Pia Davidsson, Tesfai Emahazion, C Wasslavik, L Palmqvist
Publikováno v:
Journal of Neural Transmission. 107:1065-1079
A polymorphism consisting of a deletion near the 5' splice site of exon 18 on the alpha2-macroglobulin (A2M) gene (A2M-2) has been suggested to be associated with Alzheimer's disease (AD) in family-based studies. We studied the A2M-2 allele together
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7bee86a1a4b72fb9541278a981a08de
https://doi.org/10.1007/s007020070052
https://doi.org/10.1007/s007020070052
Publikováno v:
Gene Function & Disease. 1:21-27
cDNA Sequencing of Nuclear NADH Dehydrogenase Subunit Genes in Complex I Deficient Myopathic Patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a4c3bd5bd9cf1e289c4bc4de832df4
https://doi.org/10.1002/1438-826x(200005)1:1<21::aid-gnfd21>3.0.co
https://doi.org/10.1002/1438-826x(200005)1:1<21::aid-gnfd21>3.0.co
Autor:
Anthony J. Brookes, Marianne Siegfried, W. Mathias Howell, Per-Ivan Wyöni, Jonathan A. Prince, Tesfai Emahazion, Magnus Jobs
Publikováno v:
Gene. 238:315-324
Catalogs of intra-gene polymorphisms are needed to facilitate wide-ranging candidate gene-based association studies in common complex diseases. With this in mind, we have scanned multiple alignments of expressed sequence tags and of genomic DNA seque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c444d515ca8d633118833c6eeed8cf
https://doi.org/10.1016/s0378-1119(99)00330-3
https://doi.org/10.1016/s0378-1119(99)00330-3
Autor:
Johan Jirholt, Andrew D. Cook, Tesfai Emahazion, Liselotte Jansson, Mats Sundvall, Ulf Pettersson, Niklas Nordquist, Rikard Holmdahl
Publikováno v:
European Journal of Immunology. 28:3321-3328
The genetic susceptibility to collagen-induced arthritis (CIA) in mice, the most commonly used model for rheumatoid arthritis, has been analyzed. The highly susceptible B10.RIII strain was crossed with the resistant RIIIS/J strain and the F2 intercro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d0dbc9ab00a397223144c4f972cc40
https://doi.org/10.1002/(sici)1521-4141(199810)28:10<3321::aid-immu3321>3.0.co
https://doi.org/10.1002/(sici)1521-4141(199810)28:10<3321::aid-immu3321>3.0.co
Publikováno v:
Cytogenetic and Genome Research. 82:115-119
At least 34 complex I subunits of the electron transport chain are encoded by the nuclear genome, but only 14 of these have been mapped in the human. To rapidly map additional subunits, we have performed a combination of database mining and direct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89602b019e0ebbf3db03eebea3121d4a
https://doi.org/10.1159/000015082
https://doi.org/10.1159/000015082
Publikováno v:
"Protein Engineering, Design and Selection". 8:1163-1169
Two mutant forms of human glutathione transferase (GST) A1-1 with affinity for metal ions were constructed by introduction of His residues by site-directed mutagenesis. A mutant, 2-His, contained the mutations Lys84Gln, Asp85His and Glu88His, and ano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5a44983b98fd6b3b7713ab08ba5321b
https://doi.org/10.1093/protein/8.11.1163
https://doi.org/10.1093/protein/8.11.1163
Autor:
Mats Sundvall, Henrik Arnell, Ulf Pettersson, Tesfai Emahazion, Kelm Hjälmås, Bengt Bengtsson, Martin Jagervall, Göran Annerén, Arne Stenberg, Niklas Dahl, Göran Läckgren, Christer Wassen
Publikováno v:
Journal of medical genetics. 34(5)
Primary nocturnal enuresis (PNE), or bedwetting at night, affects approximately 10% of 6 year old children. Genetic components contribute to the pathogenesis and recently one locus was assigned to chromosome 13q. We evaluated the genetic factors and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7c6ce908979a898055c0de674bc5f5b
https://pubmed.ncbi.nlm.nih.gov/9152831
https://pubmed.ncbi.nlm.nih.gov/9152831
Autor:
Tesfai Emahazion, Anthony J. Brookes
Publikováno v:
Cytogenetic and Genome Research. 82:114-114
Mapping of the NDUFA2, NDUFA6, NUDUFA7, NUDFB8, and NDUFS8 Electron Transport Chain Genes by Intron Based Radiation Hybrid Mapping.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de7a046921953777a6dd15f6bbb5b0f1
https://doi.org/10.1159/000015081
https://doi.org/10.1159/000015081