Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Tesfahun Desta"'
Publikováno v:
Journal of Dental Research. 89:609-614
Although it is known that diabetes impairs oral wound healing, relatively little is known about the cellular parameters affected, particularly in connective tissue. This study investigated the hypothesis that diabetes impairs connective tissue format
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2985bfff323464bd9205e021abb0c571
https://doi.org/10.1177/0022034510362960
https://doi.org/10.1177/0022034510362960
Autor:
Yugal Behl, Michelle F. Siqueira, Tesfahun Desta, Jingchao Li, Dan Faibish, Dana T. Graves, Javier Ortiz
Publikováno v:
The Journal of Immunology. 181:8711-8718
Osteoimmunolgy involves the interaction of the immune system with skeletal elements. This interaction can lead to the formation of osseous lesions. To investigate how the acquired immune response could contribute to osteolytic lesions, we injected th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe5f7c59d56b08f38acf2803ed45ffb
https://doi.org/10.4049/jimmunol.181.12.8711
https://doi.org/10.4049/jimmunol.181.12.8711
Publikováno v:
Journal of Periodontology. 79:1241-1247
Background: Porphyromonas gingivalis is a Gram-negative bacterium that is an important etiologic agent of human adult periodontitis. The goal of the study was to test the hypothesis that two isoforms of P. gingivalis lipopolysaccharide (PgLPS), PgLPS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e118e17cddef130508cf5e0591a05b5
https://doi.org/10.1902/jop.2008.070575
https://doi.org/10.1902/jop.2008.070575
Publikováno v:
The American Journal of Pathology. 172:1411-1418
Retinal microvascular cell loss plays a critical role in the pathogenesis of diabetic retinopathy. To examine this further, type 1 streptozotocin-induced diabetic rats and type 2 Zucker diabetic fatty rats were treated by intravitreal injection of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18295f668cb29a0e2659bcf14ebf5b48
https://doi.org/10.2353/ajpath.2008.071070
https://doi.org/10.2353/ajpath.2008.071070
Autor:
Tesfahun Desta, Dana T. Graves
Publikováno v:
Cellular Microbiology. 9:2667-2675
Porphyromonas gingivalis is an oral bacterium that causes pathology in a number of dental infections that are associated with increased fibroblast cell death. Studies presented here demonstrated that P. gingivalis stimulates cell death by apoptosis r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5474c5f63e2660b9052e9e0d9180bfb
https://doi.org/10.1111/j.1462-5822.2007.00987.x
https://doi.org/10.1111/j.1462-5822.2007.00987.x
Publikováno v:
The American Journal of Pathology. 168:757-764
Diabetics suffer increased infection followed by increased apoptosis of fibroblasts and bone-lining cells during the healing process. To investigate a potential mechanism, we inoculated Porphyromonas gingivalis into the scalp of type 2 diabetic (db/d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::954cfe4ea09d16b7331bd5fc410ddb80
https://doi.org/10.2353/ajpath.2006.050907
https://doi.org/10.2353/ajpath.2006.050907
Publikováno v:
Journal of Endotoxin Research. 11:13-18
The fimA gene encodes the major fimbrial protein of Porphyromonas gingivalis. It has been shown to stimulate adhesion to salivary proteins and other bacteria. It is also thought to play a major rol...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15d7160f0bc40aea9173ef9c33d3c1eb
https://doi.org/10.1179/096805105225006722
https://doi.org/10.1179/096805105225006722
Publikováno v:
Infection and Immunity. 73:935-943
To characterize the roles ofPorphyromonas gingivalisand its components in the disease processes, we investigated the cytokine profile induced by liveP. gingivalis, its lipopolysaccharides (LPS), and its major fimbrial protein, fimbrillin (FimA). Usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::612935424e12c08a1e34017b2b044bfd
https://doi.org/10.1128/iai.73.2.935-943.2005
https://doi.org/10.1128/iai.73.2.935-943.2005
Publikováno v:
Journal of Investigative Dermatology. 123:87-92
Diabetes has been identified as an important risk factor for infection. But relatively little is known about how diabetes alters the inflammatory response to bacteria. The objective of this study was to investigate how diabetes affects host-bacteria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba3115db957bcdb0a0ef15af8e07cf8
https://doi.org/10.1111/j.0022-202x.2004.22711.x
https://doi.org/10.1111/j.0022-202x.2004.22711.x
Publikováno v:
Endocrinology. 145:2997-3003
Diabetics suffer from both more frequent bacterial infections and greater consequences of infection. However, bacteria-induced tissue destruction and the subsequent response in diabetics have received relatively little attention. To investigate this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8c27c7d00dbcd4b756b057497d3fe69
https://doi.org/10.1210/en.2003-1601
https://doi.org/10.1210/en.2003-1601