Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Teruyoshi, Hirayama"'
Autor:
Hiroaki Kobayashi, Kenji Takemoto, Makoto Sanbo, Masumi Hirabayashi, Takahiro Hirabayashi, Teruyoshi Hirayama, Hiroshi Kiyonari, Takaya Abe, Takeshi Yagi
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109606- (2024)
Externí odkaz:
https://doaj.org/article/2a8785c53f31409e9c876b331648af26
Autor:
Teruyoshi Hirayama, Yuuki Kadooka, Etsuko Tarusawa, Sei Saitoh, Hisako Nakayama, Natsumi Hoshino, Soichiro Nakama, Takahiro Fukuishi, Yudai Kawanishi, Hiroki Umeshima, Koichi Tomita, Yumiko Yoshimura, Niels Galjart, Kouichi Hashimoto, Nobuhiko Ohno, Takeshi Yagi
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-17 (2022)
Abstract CCCTC-binding factor (CTCF) has a key role in higher-order chromatin architecture that is important for establishing and maintaining cell identity by controlling gene expression. In the mature cerebellum, CTCF is highly expressed in Purkinje
Externí odkaz:
https://doaj.org/article/a72517b6649347dfb51706d49c79da9c
Autor:
Hiroaki Kobayashi, Kenji Takemoto, Makoto Sanbo, Masumi Hirabayashi, Takahiro Hirabayashi, Teruyoshi Hirayama, Hiroshi Kiyonari, Takaya Abe, Takeshi Yagi
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105766- (2023)
Summary: Clustered protocadherin is a family of cell-surface recognition molecules implicated in neuronal connectivity that has a diverse isoform repertoire and homophilic binding specificity. Mice have 58 isoforms, encoded by Pcdhα, β, and γ gene
Externí odkaz:
https://doaj.org/article/a7d43fdbc78444aebee00075066854fa
Autor:
Hirotaka Asai, Noriaki Ohkawa, Yoshito Saitoh, Khaled Ghandour, Emi Murayama, Hirofumi Nishizono, Mina Matsuo, Teruyoshi Hirayama, Ryosuke Kaneko, Shin-ichi Muramatsu, Takeshi Yagi, Kaoru Inokuchi
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-10 (2020)
Abstract Clustered protocadherins (Pcdhs), a large group of adhesion molecules, are important for axonal projections and dendritic spread, but little is known about how they influence neuronal activity. The Pcdhβ cluster is strongly expressed in the
Externí odkaz:
https://doaj.org/article/90fae18a48a842c8babeeeab2875ff12
Autor:
Matías Alvarez-Saavedra, Keqin Yan, Yves De Repentigny, Lukas E. Hashem, Nidhi Chaudary, Shihab Sarwar, Doo Yang, Ilya Ioshikhes, Rashmi Kothary, Teruyoshi Hirayama, Takeshi Yagi, David J. Picketts
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Alterations in the homeostasis of either cortical progenitor pool, namely the apically located radial glial (RG) cells or the basal intermediate progenitors (IPCs) can severely impair cortical neuron production. Such changes are reflected by microcep
Externí odkaz:
https://doaj.org/article/d7220e31b12f4750869ddc345c3882b8
CTCF Is Required for Neural Development and Stochastic Expression of Clustered Pcdh Genes in Neurons
Publikováno v:
Cell Reports, Vol 2, Iss 2, Pp 345-357 (2012)
The CCCTC-binding factor (CTCF) is a key molecule for chromatin conformational changes that promote cellular diversity, but nothing is known about its role in neurons. Here, we produced mice with a conditional knockout (cKO) of CTCF in postmitotic pr
Externí odkaz:
https://doaj.org/article/8e927cdf062d4259852df7d1a1fde4bd
Autor:
Hiroaki Kobayashi, Kenji Takemoto, Makoto Sanbo, Masumi Hirabayashi, Takahiro Hirabayashi, Teruyoshi Hirayama, Hiroshi Kiyonari, Takaya Abe, Takeshi Yagi
Publikováno v:
SSRN Electronic Journal.
Clustered protocadherin is a family of cell-surface recognition molecules implicated in neuronal connectivity that has a diverse isoform repertoire and homophilic binding specificity. Mice have 58 isoforms, encoded by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a71b8ea3fe1effac5e42aab9c0a1be
https://doi.org/10.2139/ssrn.4156155
https://doi.org/10.2139/ssrn.4156155
Autor:
Nobuhiko Yamamoto, Takeshi Yagi, Kohei Onishi, Tsuyoshi Miyakawa, Noriyuki Sugo, Akiko Uyeda, Teruyoshi Hirayama, Satoko Hattori
Publikováno v:
J Neurosci
Genome stability is essential for brain development and function, asde novomutations during neuronal development cause psychiatric disorders. However, the contribution of DNA repair to genome stability in neurons remains elusive. Here, we demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807d961f5f4f7f72e9f3e0d1f1cdd836
https://europepmc.org/articles/PMC7672999/
https://europepmc.org/articles/PMC7672999/
Autor:
Roy H. Perlis, Hualin Simon Xi, Leonard M. Eisenberg, Sangmi Chung, Alexander A. Moghadam, Donna L. McPhie, Bruce M. Cohen, Weihua Huang, Woong Bin Kim, Patric K. Stanton, Changhong Yin, Sarah E. Cote, Teruyoshi Hirayama, Joyce Zhao, Judith L. Rapoport, Emi Fukuda, Takeshi Yagi, Kevin Eggan, Elizabeth Noyes, Sulagna Ghosh, Dost Öngür, James M. Park, Daniel R. Weinberger, Teagan Parsons, Kelvin Zheng, Joshua J. Park, Thomas A. Lanz, Karen F. Berman, Jun-Hyeong Cho, Christine T. O. Nguyen, Haneul Noh, Hae Young Kim, Joseph T. Coyle, Jose A. Apud, Peiyan Ni, Richard E. Straub, Zhicheng Shao
Publikováno v:
Nature Neuroscience. 22:229-242
We generated cortical interneurons (cINs) from induced pluripotent stem cells derived from 14 healthy controls and 14 subjects with schizophrenia. Both healthy control cINs and schizophrenia cINs were authentic, fired spontaneously, received function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a3fa6f1d2c4973104c94c13c8290d4c
https://doi.org/10.1038/s41593-018-0313-z
https://doi.org/10.1038/s41593-018-0313-z
Autor:
Teruyoshi Hirayama, Takeshi Yagi
Publikováno v:
Seminars in Cell & Developmental Biology. 69:122-130
Individual neurons are basic functional units in the complex system of the brain. One aspect of neuronal individuality is generated by stochastic and combinatorial expression of diverse clustered protocadherins (Pcdhs), encoded by the Pcdha, Pcdhb, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4ae5850c8d19d1fd0f03814479ae4d6
https://doi.org/10.1016/j.semcdb.2017.05.026
https://doi.org/10.1016/j.semcdb.2017.05.026