Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Teruo Yokokura"'
Autor:
Ikuo Kato, Naoyuki Asakawa, Teruo Yokokura, Tsuneo Matsumoto, Akinobu Kurita, Kazumi Uchida, Masaharu Onoue, Shoichi Kado, Norimasa Kaneda
Publikováno v:
Cancer Chemotherapy and Pharmacology. 67:201-213
Irinotecan hydrochloride (CPT-11) is a useful drug for cancer chemotherapy but sometimes induces severe diarrhea clinically. CPT-11 is mainly activated to SN-38 by carboxylesterase (CES) and then detoxified to SN-38 glucuronide (SN-38G) by UDP-glucur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff5dc4fa03ada194be0d9dc1c9d643c
https://doi.org/10.1007/s00280-010-1310-4
https://doi.org/10.1007/s00280-010-1310-4
Publikováno v:
The Journal of Nutrition. 137:798S-802S
Lactobacillus casei strain Shirota (LcS) has been demonstrated to have beneficial effects in numerous murine disease models via host immune modulation. It has also been reported that LcS induced recovery of host immune responses that were decreased b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d253af8190d22c72ad7d4783973fcd2f
https://doi.org/10.1093/jn/137.3.798s
https://doi.org/10.1093/jn/137.3.798s
Autor:
Yun Gi Kim, Akira Kushiro, Toshihisa Ohta, Teruo Yokokura, Takuya Takahashi, Nobuhiko Okada, Hirofumi Danbara, Koji Nomoto
Publikováno v:
Microbes and Infection. 8:994-1005
Probiotic bacteria are microorganisms that benefit the host through improvement of the balance of intestinal microflora and possibly by augmentation of host defense systems. We examined the mechanisms for the up-regulation of innate immune responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40a987e322e2649b9bbc745c4771deae
https://doi.org/10.1016/j.micinf.2005.10.019
https://doi.org/10.1016/j.micinf.2005.10.019
Autor:
Norimasa Kaneda, Masaharu Onoue, Shoichi Kado, Akinobu Kurita, Teruo Yokokura, Shusuke Hashimoto
Publikováno v:
Cancer Chemotherapy and Pharmacology. 52:349-360
Irinotecan hydrochloride (CPT-11) is a potent topoisomerase I inhibitor and is established and used widely as an antitumor agent. However, it sometimes causes severe side effects such as myelosuppression and diarrhea. These dose-limiting toxicities p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c18d4cca3b657210912ea41bf9a7e52
https://doi.org/10.1007/s00280-003-0682-0
https://doi.org/10.1007/s00280-003-0682-0
Autor:
Mami Takahashi, Takashi Sugimura, Teruo Yokokura, Keiji Wakabayashi, Satoshi Matsubara, Hideyuki Shibata, Fumiyasu Ishikawa
Publikováno v:
Biochemical and Biophysical Research Communications. 310:715-719
Since urease of Helicobacter pylori is essential for its colonization, we focused attention on foodstuffs which inhibit the activity of this enzyme. Among plant-derived 77 foodstuff samples tested, some tea and rosemary extracts were found to clearly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d16bcefbe1611ac31c4db4c572260f
https://doi.org/10.1016/j.bbrc.2003.09.066
https://doi.org/10.1016/j.bbrc.2003.09.066
Autor:
Akimitsu Takagi, Teruo Yokokura, Kimika Ishikawa, Yasunobu Yoshikai, Masato Nagaoka, Takeshi Matsuzaki, Tetsuya Matsuguchi
Publikováno v:
Clinical and Vaccine Immunology. 10:259-266
Lactobacilli are nonpathogenic gram-positive inhabitants of microflora. At least someLactobacillusstrains have been postulated to have health beneficial effects, such as the stimulation of the immune system. Here we examined the stimulatory effects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ccc4f73606de7e561f733b5b32f95c4
https://doi.org/10.1128/cdli.10.2.259-266.2003
https://doi.org/10.1128/cdli.10.2.259-266.2003
Autor:
Masaki Iimuro, Masato Nagaoka, Hideyuki Shibata, Toshihiko Kawamori, Keiji Wakabayashi, Shusuke Hashimoto, Takashi Sugimura, Naoaki Uchiya, Teruo Yokokura, Sadao Ueyama
Publikováno v:
Helicobacter. 8:59-65
Background. Recently, the acquisition by Helicobacter pylori of resistance to antibiotics has become a serious problem. Therefore, nonantibiotic substances are required to diminish H. pylori-induced gastric lesions. In the present study, the effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67c0485cc07d947e9af746e615b698e0
https://doi.org/10.1046/j.1523-5378.2003.00124.x
https://doi.org/10.1046/j.1523-5378.2003.00124.x
Autor:
Yasuto Yoshida, Wakae Yokoi, Kenji Ohishi, Haruji Sawada, Hiroshi Hatano, Ritsuo Aiyama, Tsunekazu Watanabe, Teruo Yokokura
Publikováno v:
Biological and Pharmaceutical Bulletin. 26:1125-1128
The effects of an acyl-CoA:cholesterol O-acyltransferase (ACAT) inhibitor, N-(3,5-dimethoxy-4-n-octyloxycinnamoyl)-N'-(3,4-dimethylphenyl)piperazine (YIC-C8-434), on cholesterol esterification in the intestine and liver were investigated in vitro and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06ea389206d32f3a073b91ff263084e1
https://doi.org/10.1248/bpb.26.1125
https://doi.org/10.1248/bpb.26.1125
Autor:
Koji Nomoto, Teruo Yokokura, Ryuichiro Tanaka, Masami Morotomi, Masatoshi Takahashi, Takashi Asahara, Naoya Yamashita, Hiroo Takayama, Masaharu Onoue
Publikováno v:
Clinical and Vaccine Immunology. 10:169-173
Seven Lactobacillus strains belonging to four species were evaluated for pathogenicity as well as for in vitro sensitivity to the bactericidal mechanisms of macrophages in a rabbit infective endocarditis (IE) model. Two bacteremia-associated strains,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c68a09e7160307ecca235421ada71f
https://doi.org/10.1128/cdli.10.1.169-173.2003
https://doi.org/10.1128/cdli.10.1.169-173.2003
Publikováno v:
Antimicrobial Agents and Chemotherapy. 45:1751-1760
The antimicrobial activity of the intraurethrally administered probioticLactobacillus caseistrain Shirota againstEscherichia coliin a murine urinary tract infection (UTI) model was examined. UTI was induced by intraurethral administration ofEscherich
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b06b3c6e5fffb7dc37b249b7cad358
https://doi.org/10.1128/aac.45.6.1751-1760.2001
https://doi.org/10.1128/aac.45.6.1751-1760.2001