Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Teruo Susumu"'
Autor:
Tetsuya Yoshikawa, Yuki Akiyoshi, Teruo Susumu, Hiroshi Tokado, Koichiro Fukuzaki, Ryoichi Nagata, Keiichi Samukawa, Hiroshi Iwao, Go Kito
Publikováno v:
Journal of Pharmacological Sciences, Vol 107, Iss 1, Pp 32-40 (2008)
Ginsenoside Rb1 (GRb1), a major component of the traditional herb ginseng, has been reported to show a neuroprotective effect in a rodent ischemic model. The purpose of this study was to investigate effects of GRb1 on early and delayed brain injuries
Externí odkaz:
https://doaj.org/article/cdfcaed3dcae47549dbe56f415bedd2c
Publikováno v:
Journal of Pharmacological Sciences, Vol 100, Iss 4, Pp 278-284 (2006)
Abstract.: One of the most important prognostic factors in the thrombolytic treatment of acute ischemic stroke is to recanalize. The purpose of this study was to evaluate the effectiveness and safety of urokinase in a primate thromboembolic stroke mo
Externí odkaz:
https://doaj.org/article/14d804b85d7144b0bf4b4696d247993e
Publikováno v:
Regulatory Peptides. 158:63-67
Salusin-alpha and salusin-beta are multifunctional bioactive peptides originally identified using bioinformatics analyses. Salusin-beta has been shown to exert potent hypotensive, bradycardic, and pro-atherosclerotic effects. The form in which it exi
Publikováno v:
Journal of Pharmacological Sciences, Vol 100, Iss 4, Pp 278-284 (2006)
One of the most important prognostic factors in the thrombolytic treatment of acute ischemic stroke is to recanalize. The purpose of this study was to evaluate the effectiveness and safety of urokinase in a primate thromboembolic stroke model. Thromb
Publikováno v:
Folia Pharmacologica Japonica. 127:481-484
Autor:
Chiaki Yokota, Yuji Kuge, Go Kito, Masafumi Tagaya, Hiroyasu Inoue, Teruo Susumu, Nagara Tamaki, Kazuo Minematsu
Publikováno v:
Neuroscience Letters. 341:37-40
We determined whether up to 24 h of ischemia could induce the expression of cyclooxygenase-2 (COX-2) in the brain of nonhuman primates. Randomized animals were subjected to either a 2 h ischemia (group II; n=3) or a 24 h ischemia (group III; n=3). Th
Autor:
Teruo Susumu, Go Kito, Kazuo Minematsu, Ryoichi Nagata, Yuji Kuge, Chiaki Yokota, Akira Nishimura
Publikováno v:
Journal of Neuroscience Methods. 105:45-53
To develop an experimental model of thromboembolic stroke without intracranial surgery, an autologous blood clot was delivered to the middle cerebral artery (MCA) via the internal carotid artery in cynomolgus monkeys. Male cynomolgus monkeys, in whic
Autor:
Ayumu Yoshikawa, Takaaki Senbonmatsu, Shinichiro Iida, Ken-ichi Kusano, Fukuko Kishi, Yoshimi Aizaki, Masayoshi Shichiri, Shigeyuki Nishimura, Teruo Susumu, Shoichi Ishiura
Publikováno v:
Hypertension research : official journal of the Japanese Society of Hypertension. 34(5)
The (pro)renin receptor ((P)RR), which is a recently discovered molecule of the renin-angiotensin system, plays an important role in the development of cardiovascular diseases. However, the molecular properties and the subcellular distribution of (P)
Autor:
Hiroaki Takagi, Ken-ichi Kusano, Nanao Horike, Hiroshi Takemori, Yukio Sugiyama, Hiroshi Teraoka, Yasukazu Terasaki, Kazuo Kitagawa, Osamu Hatano, Saburo Sakoda, Tsutomu Sasaki, Teruo Susumu, Naoki Oyama, Tatsuya Uebi, Yoshiki Yagita
Publikováno v:
Neuron. 69(1)
The cAMP responsive element-binding protein (CREB) functions in a broad array of biological and pathophysiological processes. We found that salt-inducible kinase 2 (SIK2) was abundantly expressed in neurons and suppressed CREB-mediated gene expressio
Autor:
Nanao, Horike, Ayako, Kumagai, Yuko, Shimono, Tomoko, Onishi, Yumi, Itoh, Tsutomu, Sasaki, Kazuo, Kitagawa, Osamu, Hatano, Hiroaki, Takagi, Teruo, Susumu, Hiroshi, Teraoka, Ken-ichi, Kusano, Yasuo, Nagaoka, Hidehisa, Kawahara, Hiroshi, Takemori
Publikováno v:
Pigment cellmelanoma research. 23(6)
cAMP response element-binding protein (CREB) promotes melanogenesis by inducing microphthalmia-associated transcription factor (Mitf ) gene expression. We report here that the CREB-specific coactivator TORC and its repressor, salt-inducible kinase 2