Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Teruo Kusano"'
Publikováno v:
Redox Biology, Vol 59, Iss , Pp 102573- (2023)
The conversion of xanthine dehydrogenase (XDH) to xanthine oxidase (XO) occurs only in mammalian species. In fresh bovine milk, the enzyme exists predominantly as the oxidase form, in contrast to various normal organs where it is found primarily as t
Externí odkaz:
https://doaj.org/article/6ecf79f0c2e741daaf6c94bccc824a3a
Autor:
Teruo Kusano, Driss Ehirchiou, Tomohiro Matsumura, Veronique Chobaz, Sonia Nasi, Mariela Castelblanco, Alexander So, Christine Lavanchy, Hans Acha-Orbea, Takeshi Nishino, Ken Okamoto, Nathalie Busso
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The roles of the convertible forms, xanthine dehydrogenase (XDH) and xanthine oxidase (XO) during tumorigenesis is not known. Here, the authors develop XDH-stable and XO-locked knock-in (ki) mice and show increased tumor growth in XO ki mice, via mac
Externí odkaz:
https://doaj.org/article/a917fab180ef4bcfad65767813174f1d
Autor:
Sonia Nasi, Mariela Castelblanco, Véronique Chobaz, Driss Ehirchiou, Alexander So, Ilaria Bernabei, Teruo Kusano, Takeshi Nishino, Ken Okamoto, Nathalie Busso
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Pathologic calcification of cartilage consists of the formation of basic calcium phosphate (BCP) and/or calcium pyrophosphate dihydrate (CPPD) containing calcium crystals in mature hyaline or articular cartilage and is associated with aging, cartilag
Externí odkaz:
https://doaj.org/article/444fb9d7d56b465aaadd3cc200cd95ae
Autor:
Masahiro Yamaguchi, Ken Okamoto, Teruo Kusano, Yoko Matsuda, Go Suzuki, Akira Fuse, Hiroyuki Yokota
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133980 (2015)
We demonstrated that 3-nitrotyrosine and 4-hydroxy-2-nonenal levels in mouse brain were elevated from 1 h until 8 h after global brain ischemia for 14 min induced with the 3-vessel occlusion model; this result indicates that ischemia reperfusion inju
Externí odkaz:
https://doaj.org/article/f17657f9cc58451a9e1ff97f4387e503
Autor:
Alexander So, Mariela Castelblanco, Hans Acha-Orbea, Tomohiro Matsumura, Véronique Chobaz, Nathalie Busso, Teruo Kusano, Takeshi Nishino, Driss Ehirchiou, Ken Okamoto, Sonia Nasi, Christine Lavanchy
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature communications, vol. 10, no. 1, pp. 4904
Nature Communications
Nature communications, vol. 10, no. 1, pp. 4904
Nature Communications
Xanthine oxidoreductase has been implicated in cancer. Nonetheless, the role played by its two convertible forms, xanthine dehydrogenase (XDH) and oxidase (XO) during tumorigenesis is not understood. Here we produce XDH-stable and XO-locked knock-in
Autor:
Alexander So, Nathalie Busso, Driss Ehirchiou, Takeshi Nishino, Mariela Castelblanco, Véronique Chobaz, Ilaria Bernabei, Ken Okamoto, Sonia Nasi, Teruo Kusano
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in cell and developmental biology, vol. 9, pp. 612440
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in cell and developmental biology, vol. 9, pp. 612440
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Pathologic calcification of cartilage consists of the formation of basic calcium phosphate (BCP) and/or calcium pyrophosphate dihydrate (CPPD) containing calcium crystals in mature hyaline or articular cartilage and is associated with aging, cartilag
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 75:1124-1144
Amyotrophic lateral sclerosis (ALS), Lou Gehrig's disease, is a progressive fatal neurodegenerative disease that involves both upper and lower motor neurons. We orally administered 4 xanthine oxidoreductase (XOR) inhibitors to G1H-G93A mice carrying
Autor:
Zenya Naito, Hiroyuki Yokota, Hisashi Yoshimura, Yoko Matsuda, Yoko Kawamoto, Toshiyuki Ishiwata, Akira Fuse, Teruo Kusano, Go Suzuki
Publikováno v:
Pathology International. 63:448-456
Nestin, a class VI intermediate filament protein, is expressed by neuronal progenitor cells in the subventricular zone (SVZ). In the present study, we analyzed the nestin expression and phosphorylation levels in nerve cells in a mouse model of cerebr
Publikováno v:
Current Pharmaceutical Design
Xanthine oxidoreductase (XOR), a complex flavoprotein, catalyzes the metabolic reactions leading from hypoxanthine to xanthine and from xanthine to urate, and both reactions take place at the molybdenum cofactor. The enzyme is a target of drugs for t
Autor:
Teruo kusano, Ken Okamoto
Publikováno v:
GOUT AND NUCLEIC ACID METABOLISM. 42:116