Zobrazeno 1 - 10
of 1 320
pro vyhledávání: '"Teruo, Okano"'
Autor:
Mitsuyoshi Nakao, Makoto Matsui, Kyungsook Kim, Nobuhiro Nishiyama, David W. Grainger, Teruo Okano, Hideko Kanazawa, Kenichi Nagase
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Background Human umbilical cord-derived mesenchymal stem cell (hUC-MSC) sheets have recently attracted attention as an alternative approach to injected cell suspensions for stem cell therapy. However, cell engraftment and cytokine expression
Externí odkaz:
https://doaj.org/article/28612099fab3433ba9b9fe1f95d5d0db
Autor:
Sumako Kameishi, Celia M. Dunn, Masatoshi Oka, Kyungsook Kim, Yun-Kyoung Cho, Sun U. Song, David W. Grainger, Teruo Okano
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Allogeneic “off-the-shelf” mesenchymal stem/stromal cell (MSC) therapy requires scalable, quality-controlled cell manufacturing and distribution systems to provide clinical-grade products using cryogenic cell banking. However, previous s
Externí odkaz:
https://doaj.org/article/e91a99820aa44a069683ec20c6c93603
Autor:
Kosuke Hamahashi, Eriko Toyoda, Miya Ishihara, Genya Mitani, Tomonori Takagaki, Nagatoshi Kaneshiro, Miki Maehara, Takumi Takahashi, Eri Okada, Ayako Watanabe, Yoshihiko Nakamura, Reiko Kato, Ryo Matoba, Takehiko Takagi, Hidenori Akutsu, Akihiro Umezawa, Hiroyuki Kobayashi, Tadashi Akamatsu, Masayuki Yamato, Teruo Okano, Masahiko Watanabe, Masato Sato
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-12 (2022)
Abstract Allogeneic cell therapies are not fully effective in treating osteoarthritis of the knee (OAK). We recently reported that transplantation of autologous chondrocyte cell-sheets along with open-wedge high tibial osteotomy promoted hyaline cart
Externí odkaz:
https://doaj.org/article/6022a8c885e640b08f1ca1d92bbb4f2c
Autor:
Masashi Noda, Kohei Tatsumi, Hideto Matsui, Yasunori Matsunari, Takeshi Sato, Yasushi Fukuoka, Akitsu Hotta, Teruo Okano, Kimihiko Kichikawa, Mitsuhiko Sugimoto, Midori Shima, Kenji Nishio
Publikováno v:
Regenerative Therapy, Vol 18, Iss , Pp 347-354 (2021)
Introduction: Gene therapy have recently attracted much attention as a curative therapeutic option for inherited single gene disorders such as hemophilia. Hemophilia is a hereditary bleeding disorder caused by the deficiency of clotting activity of f
Externí odkaz:
https://doaj.org/article/a3e5595250fe4d9daf624a5260659797
Autor:
Hallie Thorp, Kyungsook Kim, Sophia Bou-Ghannam, Makoto Kondo, Travis Maak, David W. Grainger, Teruo Okano
Publikováno v:
Regenerative Therapy, Vol 18, Iss , Pp 487-496 (2021)
Advanced tissue engineering approaches for direct articular cartilage replacement in vivo employ mesenchymal stem cell (MSC) sources, exploiting innate chondrogenic potential to fabricate hyaline-like constructs in vitro within three-dimensional (3D)
Externí odkaz:
https://doaj.org/article/e3e2a85b4c104a94a2a41d7f88aab775
Autor:
Masamichi Nakayama, Tomonori Kanno, Hironobu Takahashi, Akihiko Kikuchi, Masayuki Yamato, Teruo Okano
Publikováno v:
Science and Technology of Advanced Materials, Vol 22, Iss 1, Pp 481-493 (2021)
A variety of poly(N-isopropylacrylamide) (PIPAAm)-grafted surfaces have been reported for temperature-controlled cell adhesion/detachment. However, the surfaces reported to date need further improvement to achieve good outcomes for both cell adhesion
Externí odkaz:
https://doaj.org/article/71149aa83a0a4b5687bdad93475074bf
Autor:
Makoto Kondo, Sumako Kameishi, Kyungsook Kim, Nicolas F. Metzler, Travis G. Maak, Douglas T. Hutchinson, Angela A. Wang, Miki Maehara, Masato Sato, David W. Grainger, Teruo Okano
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-11 (2021)
Abstract Knee cartilage does not regenerate spontaneously after injury, and a gold standard regenerative treatment algorithm has not been established. This study demonstrates preclinical safety and efficacy of scaffold-free, human juvenile cartilage-
Externí odkaz:
https://doaj.org/article/6fdca4955f2f4d8a870ee72a723a6dba
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Mesenchymal stem cells (MSCs) secrete paracrine factors that play crucial roles during tissue regeneration. An increasing body of evidence suggests that this paracrine function is enhanced by MSC cultivation in three-dimensional (3D) tissue-
Externí odkaz:
https://doaj.org/article/f2eaceb8ac6043cdb8dc2f9fddbe681f
Autor:
Yu Na Lee, Hye-Jin Yi, Eun Hye Seo, Jooyun Oh, Song Lee, Sarah Ferber, Teruo Okano, In Kyong Shim, Song Cheol Kim
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-18 (2021)
Abstract Background Although pancreatic islet transplantation therapy is ideal for diabetes patients, several hurdles have prevented it from becoming a standard treatment, including donor shortage and low engraftment efficacy. In this study, we prepa
Externí odkaz:
https://doaj.org/article/08564bbe2b5f48bca64eda67269e6dc2
Autor:
Yoshiyuki Kasai, Ryo Takagi, Shinichiro Kobayashi, Toshiyuki Owaki, Naoyuki Yamaguchi, Hiroko Fukuda, Yusuke Sakai, Yoshinori Sumita, Nobuo Kanai, Hajime Isomoto, Kengo Kanetaka, Takeshi Ohki, Izumi Asahina, Kazuhiro Nagai, Kazuhiko Nakao, Naoya Takeda, Teruo Okano, Susumu Eguchi, Masayuki Yamato
Publikováno v:
Regenerative Therapy, Vol 14, Iss , Pp 87-94 (2020)
Introduction: Cultured stratified epithelial cell sheets have been clinically utilized as transplantable grafts for the regeneration of epithelial tissues, such as the esophagus, cornea, skin, and intraoral cavity. These cell sheets are expected to g
Externí odkaz:
https://doaj.org/article/72f6a459f6624a6dad23539c231293c6