Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Teruaki Nomura"'
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15365 (2010)
Hedgehog (Hh) signalling plays an important role in various developmental processes by activating the Cubitus interruptus (Ci)/Glioblastoma (Gli) family of transcription factors. In the process of proper pattern formation, Ci activity is regulated by
Externí odkaz:
https://doaj.org/article/3ebf99487a8e44559a96c40e325fef3f
Autor:
Shigenobu Yonemura, Tomohiro Yamauchi, Shunsuke Ishii, Toshie Shinagawa, Takefumi Ishidao, Yasunori Tanaka, Teruaki Nomura
Publikováno v:
The EMBO Journal. 27:1852-1862
B-Myb is one member of the vertebrate Myb family of transcription factors and is ubiquitously expressed. B-Myb activates transcription of a group of genes required for the G2/M cell cycle transition by forming the dREAM/Myb–MuvB-like complex, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c06e809067bddd246a0f7ce0787f1d
https://doi.org/10.1038/emboj.2008.118
https://doi.org/10.1038/emboj.2008.118
Publikováno v:
Journal of Biological Chemistry. 279:44582-44589
Recently we have shown that the c-myb proto-oncogene product (c-Myb) is degraded in response to Wnt-1 signaling via the pathway involving TAK1 (transforming growth factor-beta-activated kinase), HIPK2 (homeodomain-interacting protein kinase 2), and N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f630e848f5ba3fd8dd7a1d6ef16aef2b
https://doi.org/10.1074/jbc.m407831200
https://doi.org/10.1074/jbc.m407831200
Autor:
Hiroki Ito, Matiullah Khan, Jun Tanikawa, Emi Ichikawa-Iwata, Shunsuke Ishii, Hiroshi Akimaru, Teruaki Nomura, Chie Kanei-Ishii
Publikováno v:
Journal of Biological Chemistry. 279:16715-16726
The c-myb proto-oncogene product (c-Myb) regulates proliferation of hematopoietic cells by inducing the transcription of a group of target genes. Removal or mutations of the negative regulatory domain (NRD) in the C-terminal half of c-Myb leads to in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efcb1ccd0b21969b7cb76953522db51e
https://doi.org/10.1074/jbc.m313069200
https://doi.org/10.1074/jbc.m313069200
Autor:
Shunsuke Ishii, Yongsok Kim, Jun Tanikawa, Jun Ninomiya-Tsuji, Emi Ichikawa-Iwata, Kenji Kokura, Tohru Ishitani, Satoshi Kishida, Kunihiro Matsumoto, Chie Kanei-Ishii, Toshihiro Kurahashi, Teruaki Nomura
Publikováno v:
Genes & Development. 18:816-829
The c-myb proto-oncogene product (c-Myb) regulates both the proliferation and apoptosis of hematopoietic cells by inducing the transcription of a group of target genes. However, the biologically relevant molecular mechanisms that regulate c-Myb activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177ef073cbb41a7537838820d45d7288
https://doi.org/10.1101/gad.1170604
https://doi.org/10.1101/gad.1170604
Autor:
Shunsuke Ishii, Matiullah Khan, Teruaki Nomura, Tomoki Chiba, Keiji Tanaka, Hiderou Yoshida, Kazutoshi Mori
Publikováno v:
Journal of Biological Chemistry. 279:11814-11824
PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha), causes acute promyelocytic leukemias (APL). Although the role of nuclear PML-RARalpha has been extensively studied, a significant amount o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d9f3ab74e331b602b3bf98bd542da1f
https://doi.org/10.1074/jbc.m312121200
https://doi.org/10.1074/jbc.m312121200
Autor:
Shunsuke Ishii, Matiullah Khan, Chie Kanei-Ishii, Jun Harada, Kenji Kokura, Teruaki Nomura, Yongsok Kim
Publikováno v:
Journal of Biological Chemistry. 278:38998-39005
Multiple co-repressors such as N-CoR/SMRT, mSin3, and the c-ski proto-oncogene product (c-Ski) mediate the transcriptional repression induced by Mad and the thyroid hormone receptor by recruiting the histone deacetylase complex. c-Ski also binds dire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7017366724c3151788241189a73ff1c4
https://doi.org/10.1074/jbc.m307112200
https://doi.org/10.1074/jbc.m307112200
Autor:
Jun Harada, Ping Dai, Clemencia Colmenares, Matiullah Khan, Shunsuke Ishii, Renu Wadhwa, Teruaki Nomura, Hiroshi Sasaki, Sunil C. Kaul, Hiroshi Akimaru, Toshie Shinagawa
Publikováno v:
Genes & Development. 16:2843-2848
Transcription factor Glioblastoma-3 (Gli3) is cleaved in the anterior region of the limb bud to generate its repressor form. In contrast, Sonic hedgehog (Shh) signaling from the posterior zone of polarizing activity blocks Gli3 processing and then in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::187b278653bcda850a09825bded0f747
https://doi.org/10.1101/gad.1017302
https://doi.org/10.1101/gad.1017302
Autor:
Teruaki Nomura, Hyungtae Kim, Shunsuke Ishii, Sue Zhong, Renu Wadhwa, Sunil C. Kaul, Pier Paolo Pandolfi, Matiullah Khan
Publikováno v:
Journal of Biological Chemistry. 276:43491-43494
A fusion between the promyelocytic leukemia (PML) protein and the retinoic acid receptor-alpha (RARalpha) results in the transforming protein of acute promyelocytic leukemia, PML-RARalpha. PML has growth-suppressive properties and is localized within
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb024c1c4df481b249d6acd9dcbb712
https://doi.org/10.1074/jbc.c100532200
https://doi.org/10.1074/jbc.c100532200
Autor:
Renu Wadhwa, Toshie Shinagawa, Sunil C. Kaul, Matiullah Khan, Teruaki Nomura, Shunsuke Ishii, Sue Zhong, Hyungtae Kim, Emi Ichikawa-Iwata, Pier Paolo Pandolfi
Publikováno v:
Molecular Cell. 7:1233-1243
Fusion of the promyelocytic leukemia (PML) protein to the retinoic acid receptor-alpha (RARalpha) generates the transforming protein of acute promyelocytic leukemias. PML appears to be involved in multiple functions, including apoptosis and transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1efdaf674d28f7513b6e1ef5400eade5
https://doi.org/10.1016/s1097-2765(01)00257-x
https://doi.org/10.1016/s1097-2765(01)00257-x