Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Teruaki, Une"'
Autor:
Tomohiko Ueda, Kazuya Matsumoto, Teruaki Une, Hiroshi Toda, Masato Sakamoto, Kenji Suzuki, Takeshi Ochi, Akira Minamida, Yoshiaki Terauchi
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:1055-1059
Two major metabolites in humans of blonanserin, 2-(4-ethyl-1-piperazinyl)-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta-[b]pyridine (code name AD-5423), were synthesized. The first, 7-hydroxylated AD-5423, was synthesized through a four-step pro
Autor:
Tsuneyuki Yamamoto, Teruaki Une
Publikováno v:
Folia Pharmacologica Japonica. 120:173-180
Animal models of psychiatric disorders are indispensable tools to gain insights into neural mechanisms underlying these disorders and to assess potential therapeutic actions of novel compounds in preclinical settings. However, it is difficult to esta
Publikováno v:
Japanese Journal of Pharmacology. 57:197-203
The 5-hydroxytryptamine (5-HT)3 receptor binding assay using [3H]quipazine was examined. It was impossible to obtain specific [3H]quipazine binding with the membrane fractions from rat cortex prepared by the usual procedure. When the membranes were p
Publikováno v:
Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 132(6)
ブロナンセリン(ロナセン®)は大日本住友製薬株式会社で創製された新規抗精神病薬であり,ドパミンD2およびセロトニン5-HT2A受容体に対する強い遮断作用により抗精神病作用を発現す
Publikováno v:
Analytical Sciences. 18:1289-1290
Autor:
Mikio Kurokawa, Takashi Nukuda, Buichi Fujitani, Teruaki Une, Kiyoshi Furukawa, Hirofumi Okamura, Masanobu Komiya
Publikováno v:
Journal of cardiovascular pharmacology. 22(6)
We studied the in vitro vascular relaxant properties of AJ-2615, (+/-)-N-[6,11-dihydrodibenzo[b,e]-thiepin-11-yl]-4-[4- fluorophenyl]-1-piperazinebutanamide monomaleate, a novel compound with long-lasting antihypertensive activity. AJ-2615 inhibited
Purification and some properties of a hemolysin from the poisonous mushroom Rhodophyllus rhodopolius
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 28(9)
A hemolytic protein which causes diarrhea and death to mice was purified from the fruit bodies of a poisonous mushroom species Rhodophyllus rhodopolius (Fries) by DEAE-cellulose column chromatography, ammonium sulfate precipitation, gel filtration on
Publikováno v:
Japanese Journal of Pharmacology. 55:385
Publikováno v:
Japanese Journal of Pharmacology. 52:230
Autor:
Tomohiko Kawate, Hiroshi Fukushima, Mikio Taniguchi, Shin-ichi Kodato, Teruaki Une, Tohru Hino, Mitsuya Hongu, Masako Nakagawa
Publikováno v:
Chemical and Pharmaceutical Bulletin. 37:23-32
Pictet-Spengler reaction of L-tryptophan methyl ester (9) and 6-methoxy-L-tryptophan methyl ester (40) with isovaleraldehyde (10) in methylene chloride in the presence of trifluoroacetic acid gave the cis-tetrahydro-β-carboline (11, 41) as the major