Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Tertiary granule"'
Autor:
Mark P Murphy, Karen McQuillan, Fatma Gargoum, Cedric Gunaratnam, Padraig Hawkins, Niall Browne, Elaine Hayes, Le Er Saw, Clare Foley, Oliver J. McElvaney, Noel G. McElvaney, Emer P. Reeves, Kerstin Pohl
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, Vol 11 (2020)
Studies have endeavored to understand the cause for impaired antimicrobial killing by neutrophils of people with cystic fibrosis (PWCF). The aim of this study was to focus on the bacterial phagosome. Possible alterations in degranulation of cytoplasm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c26b4e6d48f3a5d29801ce45b959e2
https://doi.org/10.3389/fimmu.2020.600033
https://doi.org/10.3389/fimmu.2020.600033
Autor:
Guoyong Xu, Shian Liao, Yuanlin Yao, Xinli Zhan, Tianyou Chen, Jie Jiang, Chong Liu, Hao Li, Jiang Xue, Tuo Liang
Publikováno v:
Tuberculosis (Edinburgh, Scotland). 126
Tuberculosis infection activates the autoimmune system. However, the role of host-pathogen interactions involved in Mycobacterium tuberculosis infection is unclear. In this study, we analyzed 6 spinal tuberculosis tissues and 6 herniated disc tissues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf4007eae9b32e57156ba85ecd33d82
https://pubmed.ncbi.nlm.nih.gov/33316736
https://pubmed.ncbi.nlm.nih.gov/33316736
Publikováno v:
Amino acids. 52(8)
Taurine is a free amino acid rich in neutrophils, and neutrophils play an important role in the forefront defense against infection. Upon neutrophil activation, taurine reacts with hypochlorous acid (HOCl/OCl-) produced by the myeloperoxidase (MPO) s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb08d626c3931fb06772e3fe17e5a2b7
https://pubmed.ncbi.nlm.nih.gov/32865666
https://pubmed.ncbi.nlm.nih.gov/32865666
Autor:
Stephin J. Vervoort, Anita M.A.P. Govers, Paul J. Coffer, Arjan B. Brenkman, Ana Rita Lourenço, Jorg van Loosdregt, Marc Bierings, Rogier van Gent, Veerle Fleskens, Steven J. Ackerman, Cornelieke Pals, Marije Bartels
Publikováno v:
Blood, 125(11), 1782. American Society of Hematology
Blood, 125(11), 1782-1792. American Society of Hematology
Blood, 125(11), 1782-1792. American Society of Hematology
C/EBPε, a member of the CCAAT/enhancer binding protein (C/EBP) family of transcription factors, is exclusively expressed in myeloid cells and regulates transition from the promyelocytic stage to the myelocytic stage of neutrophil development, being
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeb0657a14540ce3b54ba1610fedc2ed
https://doi.org/10.1182/blood-2013-12-543850
https://doi.org/10.1182/blood-2013-12-543850
Publikováno v:
Winberg, L K, Jacobsen, S & Nielsen, C H 2017, ' Microparticles from patients with systemic lupus erythematosus induce production of reactive oxygen species and degranulation of polymorphonuclear leukocytes ', Arthritis Research & Therapy, vol. 19, 230 . https://doi.org/10.1186/s13075-017-1437-3
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-10 (2017)
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-10 (2017)
Arthritis Research & Therapy
Background The interaction of circulating microparticles (MPs) with immune cells in systemic lupus erythematosus (SLE) is sparsely investigated. We examined the ability of MPs from SLE patients to induce production of reactive oxygen species (ROS) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8634dee6259f97bf7f5abd92f3d5d6a8
https://doi.org/10.1186/s13075-017-1437-3
https://doi.org/10.1186/s13075-017-1437-3
Autor:
Shi Jizhong, Omer An, Lin Han, Melissa J. Fullwood, Mei Chee Lim, Mahalakshmi Shanmugasundaram, Md.Zakhir Hossain, Henry Yang, H. Phillip Koeffler, Vikas Madan, Weoi Woon Teoh, Anand Mayakonda, Pavithra Shyamsunder
Publikováno v:
Blood. 132:3834-3834
CEBPE is a member of the CCAAT/enhancer binding protein (C/EBP) family of transcription factors essential for granulocytic differentiation. CEBPE is expressed in a stage-specific manner during myeloid differentiation and regulates transition from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c198d727704d4255cc0c2111eebe845
https://doi.org/10.1182/blood-2018-99-116091
https://doi.org/10.1182/blood-2018-99-116091
Autor:
Nora Heisterkamp, David Warburton, Jess M. Cunnick, John Groffen, YoungJin Cho, Parviz Minoo, Sabine Schmidhuber, Sun-Ju Yi, Min Yu, Vesa Kaartinen, Gang Chen
Publikováno v:
Molecular and Cellular Biology, vol 29, iss 21
Bcr and Abr are GTPase-activating proteins for the small GTPase Rac. Both proteins are expressed in cells of the innate immune system, including neutrophils and macrophages. The function of Bcr has been linked to the negative regulation of neutrophil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b866cfa94132c99a4ab7e36df53faf
https://doi.org/10.1128/mcb.00357-09
https://doi.org/10.1128/mcb.00357-09
Publikováno v:
The Journal of Immunology. 182:3213-3222
The ELR-CXC chemokines play important roles in neutrophilic inflammation. We report in this study that a fully human ELR-CXC chemokine antagonist that we have generated, CXCL8(3–72)K11R/G31P (G31P), has potent anti-inflammatory effects that arise t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0b119d4c92f54136833a1513d6f0906
https://doi.org/10.4049/jimmunol.0800551
https://doi.org/10.4049/jimmunol.0800551
Autor:
Gaillard, C, Tokuyasu, TA, Rosen, G, Sotzen, J, Vitaliano-Prunier, A, Roy, R, Passegué, E, De Thé, H, Figueroa, ME, Kogan, SC
Publikováno v:
Haematologica, vol 100, iss 8
Gaillard, C; Tokuyasu, TA; Rosen, G; Sotzen, J; Vitaliano-Prunier, A; Roy, R; et al.(2015). Transcription and methylation analyses of preleukemic promyelocytes indicate a dual role for PML/RARA in leukemia initiation. Haematologica, 100(8), 1064-1075. doi: 10.3324/haematol.2014.123018. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/021421fs
Gaillard, C; Tokuyasu, TA; Rosen, G; Sotzen, J; Vitaliano-Prunier, A; Roy, R; et al.(2015). Transcription and methylation analyses of preleukemic promyelocytes indicate a dual role for PML/RARA in leukemia initiation. Haematologica, 100(8), 1064-1075. doi: 10.3324/haematol.2014.123018. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/021421fs
© 2015 Ferrata Storti Foundation. Acute promyelocytic leukemia is an aggressive malignancy characterized by the accumulation of promyelocytes in the bone marrow. PML/RARA is the primary abnormality implicated in this pathology, but the mechanisms by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a07313e048ee860ec23a60639894e98
https://doi.org/10.3324/haematol.2014.123018
https://doi.org/10.3324/haematol.2014.123018
In the foreign body response, infiltrating PMNs exocytose granule subsets to influence subsequent downstream inflammatory and wound healing events. In previous studies, we found that PMNs cultured on poly(ethylene glycol) (PEG)-containing hydrogels (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0febdee00cc1e260457bf7ad38a3cf
https://europepmc.org/articles/PMC5866922/
https://europepmc.org/articles/PMC5866922/
