Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Terry W. Williams"'
Publikováno v:
The Journal of Immunology. 119:671-674
Polymorphonuclear (PMN) leukocytes from acute pyelonephritic exudates of rats were examined for cytoxicity against various target cells. Pyelonephritic PMN leukocytes caused lysis in vitro of syngeneic renal epithelial cells in 24 to 48 hr. They also
Publikováno v:
The Journal of Immunology. 116:778-781
A population of fast sedimenting spleen cells was identified as the cause of impaired in vitro response of spleen cells to concanavalin A (Con A) in acute pyelonephritis in rats. These fast-sedimenting cells responded to Con A by suppressing the DNA
Publikováno v:
Cellular Immunology. 14:33-38
Spleen cells from rats given experimental pyelonephritis using Escherichia coli and Proteus mirabilis as infecting organisms were evaluated for their ability to respond to the mitogen Concanavalin A. Results indicate an 80% reduction in the response
Autor:
Terry W. Williams, Gale A. Granger
Publikováno v:
The Journal of Immunology. 103:170-178
The release of lymphotoxin by PHA-activated normal human lymphocytes in vitro has the following characteristics: release begins within 2 to 3 hr after derepression, long before any evidence of morphologic alteration; initiation occurs rapidly upon ex
Autor:
Terry W. Williams, Gale A. Granger
Publikováno v:
The Journal of Immunology. 102:911-918
Summary Lymphotoxin-induced cell destruction in vitro is a progressive cytolysis occurring over 36 to 48 hr. This process was shown to be temperature and concentration dependent. Cell destruction was characterized by the following observations: a) LT
Autor:
Terry W. Williams, Joseph A. Bellanti
Publikováno v:
Cellular immunology. 83(2)
In a previous study it was reported that human α-interferons (IFN) caused a significant enhancement of human lymphotoxin (LT)-induced in vitro killing of human target cells. This synergistic effect was dose dependent and was demonstrable on normal a
Publisher Summary This chapter describes a technique to examine how the secretion of lymphotoxin by lymphocytes activated in vitro may serve as a model of in vivo cellular immune reactions in which tissue destruction occurs. Suspensions of small lymp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d80837dae169efb234213cfb9549ae1
https://doi.org/10.1016/b978-0-12-107750-1.50027-3
https://doi.org/10.1016/b978-0-12-107750-1.50027-3
Publikováno v:
Nature. 221(5186)
ALLOGRAFT immunity and delayed hypersensitivity reactions are caused chiefly by the action of host immune lymphoid cells1. Although these reactions have been much studied in vivo and in vitro, the mechanism of cell destruction is essentially unknown.
Autor:
William H. Adler, null Bach, H. Fritz, null Bausher, A.C. Judith, Boyce Bennett, Barry R. Bloom, Susan Westerman Broder, K. Theodore Brunner, Jean-Charles Cerottini, Lawrence Chessin, Sidney R. Cooperband, John R. David, Roberta David, Dragan Dekaris, Sheldon Dray, Dudley C. Dumonde, Rudolf E. Falk, Robert M. Fauve, Philip R. Glade, Samuel P. Gotoff, Gale A. Granger, Jon A. Green, Harold Grotsky, Robert J. Hartzman, Ingegerd Hellström, Karl Erik Hellström, Kurt Hirschhorn, Göran Holm, Luis Jimenez, Jirˇí Johanovský, Eva Klein, William P. Kolb, Jan Krejc, H. Sherwood Lawrence, Arthur S. Lebowitz, Somsak Lolekha, Thomas C. Merigan, Jane Nishio, Barbro Nordqvist, Jan Pekárek, Hedvig Perlmann, Peter Perlmann, Edgar Pick, Ross E. Rocklin, Hans Rorsman, Steven A. Rosenberg, Nancy H. Ruddle, Samuel B. Salvin, Richard T. Smith, Mogens Sϕborg, Linda Stein, Jan Ŝvejcar, M. Takasugi, Tomoo Takiguchi, Daniel E. Thor, John L. Turk, Fred Valentine, William I. Waithe, Peter A. Ward, Terry W. Williams, Robin A. Wolstencroft, John B. Zabriskie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4257da17696c9d00e753f2bd678cb5da
https://doi.org/10.1016/b978-0-12-107750-1.50005-4
https://doi.org/10.1016/b978-0-12-107750-1.50005-4
Autor:
Terry W. Williams, Gale A. Granger
Publikováno v:
Granger, GA; & Williams, TW. (1968). Lymphocyte Cytotoxicity in vitro: Activation and Release of a Cytotoxic Factor. Nature, 218(5148), 1253-1254. doi: 10.1038/2181253a0. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/4rg6z2jw
WE have reported that cell contact per se is not sufficient to explain the rapid and dramatic in vitro destruction of target L cells observed when they are treated with immune lymphocytes or non-immune phytohaemagglutinin (PHA)-stimulated lymphocytes