Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Terry W Bilverstone"'
Autor:
Terry W Bilverstone, Megan Garland, Rory J Cave, Michelle L Kelly, Martina Tholen, Donna M Bouley, Philip Kaye, Nigel P Minton, Matthew Bogyo, Sarah A Kuehne, Roman A Melnyk
Publikováno v:
PLoS Pathogens, Vol 16, Iss 9, p e1008852 (2020)
Enzymatic inactivation of Rho-family GTPases by the glucosyltransferase domain of Clostridioides difficile Toxin B (TcdB) gives rise to various pathogenic effects in cells that are classically thought to be responsible for the disease symptoms associ
Externí odkaz:
https://doaj.org/article/a157c6602b164a1b842cd03189db0e84
Autor:
Jorge Monteford, Patrick Ingle, Terry W. Bilverstone, Sheryl Philip, Nigel P. Minton, Sarah A. Kuehne
Publikováno v:
Anaerobe
Clostridioides difficile R20291 is the most studied PCR-Ribotype 027 isolate. The two predominant lineages of this hypervirulent strain, however, exhibit substantive phenotypic differences and possess genomes that differ by a small number of nucleoti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dee99c2a6faa0d035d9c75ba0afb4d9
Autor:
William A. Petri, Jashim Uddin, Sarah A. Kuehne, Carsten Schwan, Morgan Simpson, Natasha Marin, Terry W. Bilverstone, William A Petri, Jhansi L. Leslie, Alexandra N. Donlan, Nigel P. Minton
Clostridioides difficile is the leading cause of hospital-acquired gastrointestinal infection, in part due to the existence of binary toxin (CDT)-expressing hypervirulent strains. We have previously shown that CDT interacts with the TLR2/6 heterodime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::317296b65797fa7ed2033936f7899b37
https://doi.org/10.1101/2021.08.03.454966
https://doi.org/10.1101/2021.08.03.454966
Publikováno v:
Anaerobe
The production of TcdA, TcdB and CDT in Clostridium difficile PCR ribotype 027, is regulated by the two-component system response regulator CdtR. Despite this, little is known about the signal transduction pathway leading to the activation of CdtR. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5025cda93b8e3e9c0ccb55c4c6aa735
https://doi.org/10.1016/j.anaerobe.2019.102074
https://doi.org/10.1016/j.anaerobe.2019.102074
Autor:
Lücke A, Michelle Lister, Whittle M, Sarah A. Kuehne, Nigel P. Minton, van Esveld R, Terry W. Bilverstone
Bacteriophage represent a promising option for the treatment of Clostridioides difficile (formerly Clostridium difficile) infection (CDI), which at present relies on conventional antibiotic therapy. The specificity of bacteriophages should prevent th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d60ac566320518abe2603e4b08e5aba8
https://doi.org/10.1101/2021.05.26.445907
https://doi.org/10.1101/2021.05.26.445907
Publikováno v:
Anaerobe
Assessing the regulation of Clostridium difficile transferase (CDT), is complicated by the presence of a Pathogenicity locus (PaLoc) which encodes Toxins A and B. Here we developed R20291ΔPaLoc model strains and cell-based assays to quantify CDT-med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6df6b220bffc7c2d4f6b3582cbeb8f7
http://europepmc.org/articles/PMC5408908
http://europepmc.org/articles/PMC5408908
Autor:
Nigel P. Minton, Roman A. Melnyk, Michelle L. Kelly, Megan Garland, Sarah A. Kuehne, Matthew Bogyo, Terry W. Bilverstone, Martina Tholen, Philip Kaye, Rory J. Cave, Donna M. Bouley
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 9, p e1008852 (2020)
PLoS Pathogens, Vol 16, Iss 9, p e1008852 (2020)
Enzymatic inactivation of Rho-family GTPases by the glucosyltransferase domain of Clostridioides difficile Toxin B (TcdB) gives rise to various pathogenic effects in cells that are classically thought to be responsible for the disease symptoms associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::825a8124629abd117a743051d3580850
https://doi.org/10.1371/journal.ppat.1008852
https://doi.org/10.1371/journal.ppat.1008852
Publikováno v:
Journal of the American Society of Brewing Chemists. 73:347-353
Volatile esters are amongst the most important yeast-derived flavor-active compounds produced during brewery fermentation. Dissolved oxygen concentration has long been recognized as an effector for...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d18667e4c20c38370f014f7c9469c05c
https://doi.org/10.1094/asbcj-2015-0730-01
https://doi.org/10.1094/asbcj-2015-0730-01