Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Terry T. Takahashi"'
Autor:
Brian J. Grindel, Brian J. Engel, Carolyn G. Hall, Lindsay E. Kelderhouse, Anthony Lucci, Niki M. Zacharias, Terry T. Takahashi, Steven W. Millward
Publikováno v:
ACS Omega, Vol 5, Iss 39, Pp 25440-25455 (2020)
Externí odkaz:
https://doaj.org/article/3419793f86564e46a3ce84aad1828161
Autor:
Brian J. Grindel, Brian J. Engel, Justin N. Ong, Anupallavi Srinivasamani, Xiaowen Liang, Niki M. Zacharias, Robert C. Bast, Michael A. Curran, Terry T. Takahashi, Richard W. Roberts, Steven W. Millward
Publikováno v:
ACS chemical biology. 17(6)
Therapeutic monoclonal antibodies directed against PD-L1 (e.g., atezolizumab) disrupt PD-L1:PD-1 signaling and reactivate exhausted cytotoxic T-cells in the tumor compartment. Although anti-PD-L1 antibodies are successful as immune checkpoint inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2b3a6a3aba43361522ba93b0bee5c44
https://pubmed.ncbi.nlm.nih.gov/35611948
https://pubmed.ncbi.nlm.nih.gov/35611948
Autor:
Steven W. Millward, Brian J. Grindel, Anthony Lucci, Lindsay E. Kelderhouse, Carolyn G. Hall, Niki M. Zacharias, Terry T. Takahashi, Brian J. Engel
Publikováno v:
ACS Omega
ACS Omega, Vol 5, Iss 39, Pp 25440-25455 (2020)
ACS Omega, Vol 5, Iss 39, Pp 25440-25455 (2020)
Directed evolution is a powerful tool for the selection of functional ligands from molecular libraries. Extracellular domains (ECDs) of cell surface receptors are common selection targets for therapeutic and imaging agent development. Unfortunately,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe796cd60505cfd852a7c28b31bcb9a
http://europepmc.org/articles/PMC7542843
http://europepmc.org/articles/PMC7542843
Autor:
Steven W. Millward, Brian J. Engel, Michael A. Curran, Terry T. Takahashi, Richard W. Roberts, Golnaz Kamalinia, Brian J. Grindel, Justin N. Ong, Anupallavi Srinivasamani
Publikováno v:
ACS Chemical Biology. 15:1630-1641
Programmed death ligand 1 (PD-L1) is a critical immune checkpoint ligand whose overexpression on tumor cells provides a mechanism of escape from immune surveillance. The interaction between PD-L1 and PD-1 on T cell lymphocytes suppresses both T cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f962f090ff415723a5d4e771d36e331e
https://doi.org/10.1021/acschembio.0c00264
https://doi.org/10.1021/acschembio.0c00264
A Neural Model of Auditory Space Compatible with Human Perception under Simulated Echoic Conditions.
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137900 (2015)
In a typical auditory scene, sounds from different sources and reflective surfaces summate in the ears, causing spatial cues to fluctuate. Prevailing hypotheses of how spatial locations may be encoded and represented across auditory neurons generally
Externí odkaz:
https://doaj.org/article/5fb71d523a1b4281950ff5e9d8ba5388
Autor:
Brian J. Grindel, Richard W. Roberts, Terry T. Takahashi, Golnaz Kamalinia, Steven W. Millward
Publikováno v:
Chem Soc Rev
mRNA display is a powerful biological display platform for the directed evolution of proteins and peptides. mRNA display libraries covalently link the displayed peptide or protein (phenotype) with the encoding genetic information (genotype) through t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67151a0fe0c4653cf6e6127d7f4488bb
https://pubmed.ncbi.nlm.nih.gov/34165126
https://pubmed.ncbi.nlm.nih.gov/34165126
Autor:
Noah Malmstadt, Richard W. Roberts, Kenmond Pang, Wan-Zhen Sophie Lin, William E. Evenson, Alexander T. Czaja, Terry T. Takahashi, Farzad Jalali-Yazdi
Publikováno v:
Analytical chemistry. 92(15)
Modern genomic sequencing efforts are identifying potential diagnostic and therapeutic targets more rapidly than existing methods can generate the peptide- and protein-based ligands required to study them. To address this problem, we have developed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bba35be2d887789271fedac86642a54
https://pubmed.ncbi.nlm.nih.gov/32633489
https://pubmed.ncbi.nlm.nih.gov/32633489
Autor:
Aaron T. Balana, Terry T. Takahashi, Somnath Mukherjee, Matthew R. Pratt, Stuart P. Moon, David Baker, Nichole J. Pedowitz, Paul M. Levine, Timothy W. Craven, Christian F. W. Becker
Publikováno v:
Nature chemistry
A major role for the intracellular posttranslational modification O-GlcNAc appears to be the inhibition of protein aggregation. Most of the previous studies in this area have focused on O-GlcNAc modification of the amyloid-forming proteins themselves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7c121f2de19ef93aa76e536a571fae
https://pubmed.ncbi.nlm.nih.gov/33931750
https://pubmed.ncbi.nlm.nih.gov/33931750
Autor:
Brian S Nelson, Terry T Takahashi
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3598 (2008)
Despite their prevalence in nature, echoes are not perceived as events separate from the sounds arriving directly from an active source, until the echo's delay is long. We measured the head-saccades of barn owls and the responses of neurons in their
Externí odkaz:
https://doaj.org/article/10af50a1c0724529a3a5c50971539ab2
Publikováno v:
PLoS ONE, Vol 2, Iss 7, p e675 (2007)
The relationship between neuronal acuity and behavioral performance was assessed in the barn owl (Tyto alba), a nocturnal raptor renowned for its ability to localize sounds and for the topographic representation of auditory space found in the midbrai
Externí odkaz:
https://doaj.org/article/612806e9f6f84f00a314eb3ec830129a