Výsledky vyhledávání - "Terry T. Gentzler"

The in vivo efficacy and side effect pharmacology of GS ‐5759, a novel bifunctional phosphodiesterase 4 inhibitor and long‐acting β 2 ‐adrenoceptor agonist in preclinical animal species

Autor: Zhi-Hua Cui, Michael Salmon, Clifford D. Wright, Melanie Doyle-Eisele, Eric A. Sorensen, Karin Rudolph, Edward G. Barrett, Gary B. Phillips, Philip J. Kuehl, Lafe J. Purvis, Christopher Royer, Musong Kim, Stacey L. Tannheimer, Kimberly C. Hartsough, Terry T. Gentzler, William R. Baker, Jacob D. McDonald

Publikováno v: Pharmacology Research & Perspectives. 2

Bronchodilators are a central therapy for symptom relief in respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma, with inhaled β 2-adrenoceptor agonists and anticholinergics being the primary treatments available. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ee0c3839086fffc4593bfbb9b2f09516
https://doi.org/10.1002/prp2.46

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GS-5759, A Novel Bi-Functional Phosphodiesterase 4 Inhibitor And Long-Acting ²2-Adrenoceptor Agonist, In Vivo Characterization Of The Bronchodilator Pharmacology And Safety In Guinea Pigs

Autor: Terry T. Gentzler, Zhi-Hua Cui, Clifford D. Wright, Michael Salmon

Publikováno v: A31. PATHOGENESIS OF COPD AND EMPHYSEMA IN MICE AND MEN.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::65c82257e74c13426c71141daa149747
https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a1282

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GS-5759, A Novel Bi-functional Phosphodiesterase 4 Inhibitor And Long-Acting ²2-Adrenoceptor Agonist Is Efficacious In Rodent Models Of Pulmonary Inflammation And Does Not Cause Emesis In Ferrets

Autor: Karin Rudolph, Melanie Doyle-Eisele, Michael Salmon, Jacob D. McDonald, Zhi-Hua Cui, Terry T. Gentzler, Edward G. Barrett, Kimberley C. Hartsough

Publikováno v: D35. PHOSPHODIESTERASE INHIBITORS AS THERAPEUTICS FOR LUNG DISEASES.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::79ec10b8675b0f831c984e3c0b87aee9
https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a5696

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GS-5759, A Novel Bi-Functional Phosphodiesterase 4 Inhibitor And Long-Acting ²2-Adrenoceptor Agonist, In Vitro Pharmacology On Guinea Pig Tracheal Smooth Muscle Strips

Autor: Terry T. Gentzler, Zhi-Hua Cui, Michael Salmon

Publikováno v: D35. PHOSPHODIESTERASE INHIBITORS AS THERAPEUTICS FOR LUNG DISEASES.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ebfab571fd801022596522448aa14b2d
https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a5704

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