Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Terry Shaw"'
Autor:
Lindsey Terry, Victoria Chell, Samantha Newland, Pamela Acheson-Dossang, Douglas S. Williamson, Gitte Mikkelsen, Garrick Paul Smith, Allan E. Surgenor, Yikang Wang, Simon Bedford, Kenneth Vielsted Christensen, Pawel Dokurno, Lassina Badolo, Terry Shaw, Morten Hentzer, Stuart C. Ray, Chen I-Jen, Thomas Jensen
Publikováno v:
Journal of Medicinal Chemistry. 64:10312-10332
Inhibitors of leucine-rich repeat kinase 2 (LRRK2) and mutants, such as G2019S, have potential utility in Parkinson's disease treatment. Fragment hit-derived pyrrolo[2,3-d]pyrimidines underwent optimization using X-ray structures of LRRK2 kinase doma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8df5fa0cec15de8f0cc2397b29b493b
https://doi.org/10.1021/acs.jmedchem.1c00720
https://doi.org/10.1021/acs.jmedchem.1c00720
Autor:
Douglas S, Williamson, Garrick P, Smith, Gitte K, Mikkelsen, Thomas, Jensen, Pamela, Acheson-Dossang, Lassina, Badolo, Simon T, Bedford, Victoria, Chell, I-Jen, Chen, Pawel, Dokurno, Morten, Hentzer, Samantha, Newland, Stuart C, Ray, Terry, Shaw, Allan E, Surgenor, Lindsey, Terry, Yikang, Wang, Kenneth V, Christensen
Publikováno v:
Journal of medicinal chemistry. 64(14)
Inhibitors of leucine-rich repeat kinase 2 (LRRK2) and mutants, such as G2019S, have potential utility in Parkinson's disease treatment. Fragment hit-derived pyrrolo[2,3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::66aec7ec58df96de5ee4c65273396900
https://pubmed.ncbi.nlm.nih.gov/34184879
https://pubmed.ncbi.nlm.nih.gov/34184879
Autor:
Angela K. Henneberger, Mark Lachowicz, Terry Shaw, Laura M. Stapleton, Michael E. Woolley, Tessa L. Johnson, Yi Feng, Daniel Bonnéry, Bess A. Rose, Yating Zheng
Publikováno v:
Journal of Research on Educational Effectiveness. 12:616-647
There is demand among policy-makers for the use of state education longitudinal data systems, yet laws and policies regulating data disclosure limit access to such data, and security concerns and r...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a0355673c4d1da502768530f013eac9
https://doi.org/10.1080/19345747.2019.1631421
https://doi.org/10.1080/19345747.2019.1631421
Publikováno v:
Forest Ecosystems. 9:100038
Large trees have disproportionally large competitive advantage in access to light, which has been proposed to increase growth dominance of large trees (e.g., accounting for a larger proportion of growth than volume of a stand). Tree growth may also b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f9b109d61afc06bb1e22ae4ebbebea
https://doi.org/10.1016/j.fecs.2022.100038
https://doi.org/10.1016/j.fecs.2022.100038
Autor:
Chen I-Jen, Simon Bedford, Kenneth Vielsted Christensen, Victoria Chell, Allan E. Surgenor, Lindsey Terry, Justus Claus Alfred Daechsel, Kenneth Thirstrup, Samantha Newland, Jonathan D. Moore, Garrick Paul Smith, Pamela Acheson-Dossang, Martin C. Herzig, Stuart C. Ray, Zoe Daniels, Roderick E. Hubbard, James Brooke Murray, Douglas S. Williamson, Pawel Dokurno, Morten Hentzer, Yikang Wang, Terry Shaw, Laurent David
Publikováno v:
Journal of Medicinal Chemistry. 60:8945-8962
Mutations in leucine-rich repeat kinase 2 (LRRK2), such as G2019S, are associated with an increased risk of developing Parkinson’s disease. Surrogates for the LRRK2 kinase domain based on checkpoint kinase 1 (CHK1) mutants were designed, expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de891ae3a7927d47b4fdf8368236edb1
https://doi.org/10.1021/acs.jmedchem.7b01186
https://doi.org/10.1021/acs.jmedchem.7b01186
Publikováno v:
Northwest Science. 93:163
Tree susceptibility and suitability for herbivorous insects depends upon a wide array of chemical compounds including potential toxins such as monoterpenes. Silvicultural techniques such as thinning and fertilization may change the concentration of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c307bb6a8c4ee0c803fefbbe5dc178d7
https://doi.org/10.3955/046.093.0301
https://doi.org/10.3955/046.093.0301
Autor:
Cason Jones, Lee Adler, Barry McBroom, David Yi, Christine Sammer, Loran D. Hauck, Terry Shaw, David C. Classen, Michael Li
Publikováno v:
Journal of Patient Safety
Supplemental digital content is available in the text.
Objective The aim of this study was to determine the impact of all-cause inpatient harms on hospital finances and patient clinical outcomes. Research Design A retrospective analysis of inpat
Objective The aim of this study was to determine the impact of all-cause inpatient harms on hospital finances and patient clinical outcomes. Research Design A retrospective analysis of inpat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9503871afd152050a65e0baecd1ca8fd
http://europepmc.org/articles/PMC5965919
http://europepmc.org/articles/PMC5965919
Autor:
Stephen Stokes, Patrick C. Mahon, Alan D. Robertson, Jalanie D’Alessandro, Paul Webb, Charles Parry, Lisa Baker, Natalia Matassova, Nicholas G. M. Davies, Sean McKenna, Andrew Massey, Rachel Parsons, Yikang Wang, Macias Alba, Paul Brough, Ben Davis, Michael Wood, Simon Bedford, Jonathan D. Moore, Christopher J. Northfield, Loic le Strat, Stephen D. Roughley, Daniel Maddox, Seema Chavda, James Brooke Murray, Allan E. Surgenor, Johannes W. G. Meissner, Terry Shaw, Heather Simmonite, Stefaniak Emma Jayne, Victoria Chell, Neil Whitehead, Kirsten Brown
Publikováno v:
Journal of medicinal chemistry. 60(6)
Libraries of nonpurified resorcinol amide derivatives were screened by surface plasmon resonance (SPR) to determine the binding dissociation constant (off-rate, kd) for compounds binding to the pyruvate dehydrogenase kinase (PDHK) enzyme. Parallel of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb5f231f5660155f00b4666296b0e799
https://pubmed.ncbi.nlm.nih.gov/28199108
https://pubmed.ncbi.nlm.nih.gov/28199108
Autor:
Mark D. Coleman, Mark J. Kimsey, Deborah S. Page-Dumroese, Kevin P. White, Paul E. Gessler, Terry Shaw
Publikováno v:
Forest Ecology and Management. 286:101-107
Douglas-fir ( Pseudotsuga menziesii [Mirb.] Franco) in the Inland Northwest region of the USA are nitrogen (N) deficient; however stem growth responses to N fertilizers are unpredictable, which may be due to poor accounting of other limiting nutrient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd0892dc0ca15bca41ab9eeae6d8ea3c
https://doi.org/10.1016/j.foreco.2012.08.043
https://doi.org/10.1016/j.foreco.2012.08.043
Publikováno v:
SAE International Journal of Engines. 4:1235-1246
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f9673383b5f1baff5789c8988da4069
https://doi.org/10.4271/2011-01-0938
https://doi.org/10.4271/2011-01-0938