Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Terry P. Combs"'
Autor:
Terry P. Combs, Jingchun Luo, Judith B. Borja, Karen L. Mohlke, Ethan M. Lange, Omar AbdelBaky, Christopher W. Kuzawa, Damien C. Croteau-Chonka, Marie P. Fogarty, Leslie A. Lange, Linda S. Adair, Ying Wu, Thomas W. McDade, Yun Li
Publikováno v:
Human Molecular Genetics. 21:463-471
Adiponectin is a protein hormone that can affect major metabolic processes including glucose regulation and fat metabolism. Our previous genome-wide association (GWA) study of circulating plasma adiponectin levels in Filipino women from the Cebu Long
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f37dfe7af8168c7a35de73b2d522a3f
https://doi.org/10.1093/hmg/ddr480
https://doi.org/10.1093/hmg/ddr480
Autor:
Benjamin D. Medoff, Michael J. Raher, Philipp E. Scherer, Meiqian Weng, Kenneth D. Bloch, Terry P. Combs, Patricio Leyton
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 45:340-347
Remodeling of the pulmonary arteries is a common feature among the heterogeneous disorders that cause pulmonary hypertension. In these disorders, the remodeled pulmonary arteries often demonstrate inflammation and an accumulation of pulmonary artery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77df50c9d90e54391675945b87c77dbb
https://doi.org/10.1165/rcmb.2010-0316oc
https://doi.org/10.1165/rcmb.2010-0316oc
Autor:
James A. Swenberg, Mats Stridsberg, Kevin Flurkey, David E. Harrison, J. McKee Alderman, Sneha B. Naik, Linhong Jing, Urmila Srinivas, Terry P. Combs, Xian Chen, Natasha L. Brooks, Jonathan M. Gutierrez, Carol E. Parker, Simon Klebanov, Rod Bronson, Kristen B. Ziara, Gunnar Boysen
Publikováno v:
Experimental Gerontology. 44:26-33
Pit1 null (Snell dwarf) and Proph1 null (Ames dwarf) mutant mice lack GH, PRL and TSH. Snell and Ames dwarf mice also exhibit reduced IGF-I, resistance to cancer and a longer lifespan than control mice. Endogenous glucose production during fasting is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5c9462a27a0b0b955bd742ec2a11579
https://doi.org/10.1016/j.exger.2008.05.014
https://doi.org/10.1016/j.exger.2008.05.014
Publikováno v:
Obesity. 15:1419-1429
Objective: The objective of this study was to assess long-term metabolic consequences of total body irradiation (TBI) and bone marrow transplantation. Severe obesity develops due to both hypertrophy and hyperplasia of adipocytes. We hypothesized that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a1f399b552838ce325978151563c17c
https://doi.org/10.1038/oby.2007.170
https://doi.org/10.1038/oby.2007.170
Autor:
Terry P. Combs, Omar AbdelBaky, Laura Iberkleid, Roland Tisch, Marie Lamarche, David M. Maahs, Philipp E. Scherer, Janet K. Snell-Bergeon, Bryan C. Bergman, Errol B. Marliss
Circulating adiponectin is elevated in human type 1 diabetes (T1D) and nonobese diabetic (NOD) mice without the expected indications of adiponectin action, consistent with tissue resistance.Adiponectin stimulates hepatocyte production of the suppress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194d9bbcb532865d9c34940dba79b9b4
https://europepmc.org/articles/PMC4524989/
https://europepmc.org/articles/PMC4524989/
Autor:
Nagajyothi, Stephen M. Factor, Shankar Mukherjee, David Jayabalan, Cecilia J. de Almeida, Linda A. Jelicks, Aisha Cordero, Dazhi Zhao, Vicki L. Braunstein, Louis M. Weiss, Michael P. Lisanti, Philipp E. Scherer, Herbert B. Tanowitz, Ying Lin, Terry P. Combs, Shira Landskroner-Eiger, William Schubert
Publikováno v:
Journal of Biological Chemistry. 280:24085-24094
Adipose tissue plays an active role in normal metabolic homeostasis as well as in the development of human disease. Beyond its obvious role as a depot for triglycerides, adipose tissue controls energy expenditure through secretion of several factors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f4d22e701a87f3c0385b7ec34dd463d
https://doi.org/10.1074/jbc.m412802200
https://doi.org/10.1074/jbc.m412802200
Autor:
Brent Rollman, Xueliang Du, Meredith Hawkins, Nir Barzilai, Christopher J. Rhodes, Anders H. Berg, Ying Lin, Weijie Li, Terry P. Combs, Philipp E. Scherer, Michael W. Rajala, Puneeth Iyengar, Adria Giacca, Michael Brownlee, I. George Fantus, Tony K.T. Lam
Publikováno v:
Journal of Biological Chemistry. 280:4617-4626
Hyperglycemia is a major independent risk factor for diabetic macrovascular disease. The consequences of exposure of endothelial cells to hyperglycemia are well established. However, little is known about how adipocytes respond to both acute as well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4aa3585cdc6f75f9a6aaa6f3ab0c24c8
https://doi.org/10.1074/jbc.m411863200
https://doi.org/10.1074/jbc.m411863200
Publikováno v:
Canadian Journal of Diabetes. 40:S55-S56
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::025d678fa434617bb9ad9c283699fd1f
https://doi.org/10.1016/j.jcjd.2016.08.156
https://doi.org/10.1016/j.jcjd.2016.08.156
Autor:
William Schubert, Anthony W. Ashton, Terence M. Williams, Terry P. Combs, Freddy A. Medina, Hyangkyu Lee, Jeffrey B. Wyckoff, Michael P. Lisanti, Scott Eric Woodman
Publikováno v:
The American Journal of Pathology. 162:2059-2068
Recent studies have shown that caveolin-1 (Cav-1) plays an important role as a regulator of angiogenesis in vitro. Here, we use Cav-1 knockout (KO) mice as a model system to examine the in vivo relevance of these findings. A primary mediator of angio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e72f4eedbd14f2339086b531a297057
https://doi.org/10.1016/s0002-9440(10)64337-4
https://doi.org/10.1016/s0002-9440(10)64337-4
Autor:
Philipp E. Scherer, Anders H. Berg, Terry P. Combs, Michael Brownlee, Utpal B. Pajvani, Xueliang Du, Michael W. Rajala, Therese Schulthess, Jürgen Engel
Publikováno v:
Journal of Biological Chemistry. 278:9073-9085
Acrp30/adiponectin is an adipocyte-specific secretory protein that has recently been implicated as a mediator of systemic insulin sensitivity with liver and muscle as target organs. Acrp30 is found as two forms in serum, as a lower molecular weight t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f566eccc6771c13bdef0ca9827ea86e
https://doi.org/10.1074/jbc.m207198200
https://doi.org/10.1074/jbc.m207198200