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pro vyhledávání: '"Terry L. Delovitch"'
Autor:
Terry L. Delovitch
Publikováno v:
Frontiers in Immunology, Vol 6 (2015)
Externí odkaz:
https://doaj.org/article/eee8f562f08a4f349e4c1854dbf05ee0
Autor:
Lakshmimathy Subramanian, Hartley Blumenfeld, Robert Tohn, Dalam Ly, Carlos Aguilera, Igor Maricic, Jan-Eric Mansson, Karsten Buschard, Vipin Kumar, Terry L. Delovitch
Publikováno v:
PLoS ONE, Vol 7, Iss 7 (2012)
Externí odkaz:
https://doaj.org/article/c4de26d32d89488dbf657a13edd9090e
Publikováno v:
Clinical and Experimental Immunology. 166:121-133
Summary Because invariant natural killer T (iNK T) cells link innate and adaptive immunity, the structure-dependent design of iNK T cell agonists may have therapeutic value as vaccines for many indications, including autoimmune disease. Previously, w
Autor:
Steven A. Porcelli, Natacha Veerapen, Gurdyal S. Besra, S. M. M. Haeryfar, H. Blumenfeld, R. Tohn, Terry L. Delovitch
Publikováno v:
Clinical and Experimental Immunology. 164:26-41
Summary We have reported previously that treatment of non-obese diabetic (NOD) mice with the invariant natural killer T (iNK T) cell agonist α-galactosylceramide C26:0 (α-GalCer) or its T helper type 2 (Th2)-biasing derivative α-GalCer C20:2 (C20:
Autor:
Luc Van Kaer, Lisa A. Mannik, Ian Chin-Yee, Shayan Sharif, Terry L. Delovitch, S. M. Mansour Haeryfar
Publikováno v:
Immunology. 132:361-375
Invariant natural killer T (iNKT) cells are a small subset of lymphocytes that recognize glycolipid antigens in the context of CD1d and consequently produce large quantities of pro-inflammatory and/or anti-inflammatory cytokines. Several transmembran
Autor:
William W. Cruikshank, Wei Chen, Konstantin V. Salojin, Craig Meagher, Qing Sheng Mi, Noah Horst, Josh Beilke, G A Arreaza, Terry L. Delovitch
Publikováno v:
Diabetes
OBJECTIVE The progressive infiltration of pancreatic islets by lymphocytes is mandatory for development of autoimmune type 1 diabetes. This inflammatory process is mediated by several mediators that are potential therapeutic targets to arrest develop
Autor:
A. M. Jevnikar, William W. Cruikshank, H. Diao, C. Du, Terry L. Delovitch, Shuang Wang, Qiunong Guan
Publikováno v:
Kidney International. 73(3):318-326
T-cell-mediated renal injury is a major cause of kidney transplant rejection and renal failure; hence, understanding T-cell migration within the kidney is important for preventing renal injury. Interleukin (IL)-16 is a T-cell chemoattractant produced
The future is now—this groundbreaking textbook illustrates how biotechnology has radically changed the way we think about health care Biotechnology is delivering not only new products to diagnose, prevent, and treat human disease but entirely new a
Autor:
Shabbir Hussain, Terry L. Delovitch
Publikováno v:
The Journal of Immunology. 179:7225-7232
Although B cells play a pathogenic role in the initiation of type 1 diabetes (T1D) in NOD mice, it is not known whether activated B cells can maintain tolerance and transfer protection from T1D. In this study, we demonstrate that i.v. transfusion of