Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Terry Jianguo, Zhang"'
Publikováno v:
Orthopaedic Surgery, Vol 16, Iss 12, Pp 3129-3140 (2024)
ABSTRACT Objectives Understanding the patterns and implications of coexisting musculoskeletal conditions is crucial for developing effective management strategies and improving care for older adults. This study aimed to examine the associations betwe
Externí odkaz:
https://doaj.org/article/f5d01e98c30441a0adca704b3ad70a0a
Publikováno v:
Aging Medicine, Vol 7, Iss 5, Pp 596-605 (2024)
Abstract Objectives The burden of pain in middle‐aged and older adults is considerable and significantly increases healthcare expenditures. We aimed to investigate the roles of handgrip strength (HGS) weakness and asymmetry in predicting pain acros
Externí odkaz:
https://doaj.org/article/2ae1cdca476a4212818e481003516f4d
Autor:
Guozhuang Li, Kexin Xu, Xiangjie Yin, Jianle Yang, Jihao Cai, Xinyu Yang, Qing Li, Jie Wang, Zhengye Zhao, Aoran Mahesahti, Ning Zhang, Terry Jianguo Zhang, Nan Wu
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-7 (2024)
Abstract Phenotypes play a fundamental role in medical genetics, serving as external manifestations of underlying genotypes. Deep phenotyping, a cornerstone of precision medicine, involves precise multi-system phenotype assessments, facilitating dise
Externí odkaz:
https://doaj.org/article/fd75a92a0d754c01b7a0b0048c16eedd
Autor:
Kexin Xu, Guozhuang Li, Zhihong Wu, Terry Jianguo Zhang, Nan Wu, On behalf of the Chinese Multi-Disciplinary Working Group on the Ehlers-Danlos Syndromes
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-6 (2024)
Abstract Background The Ehlers-Danlos syndromes (EDS) are a group of rare hereditary connective tissue disorders. EDS is clinically and genetically heterogeneous and usually involves multiple systems. There are 14 subtypes of EDS with hallmark featur
Externí odkaz:
https://doaj.org/article/82db6927b78a4b63bcf58092e75dd8dc
Autor:
Muchuan Wang, Ziquan Li, Sen Zhao, Zhifa Zheng, Yipeng Wang, Guixing Qiu, Zhihong Wu, Nan Wu, Terry Jianguo Zhang, Siyi Cai
Publikováno v:
Cell Regeneration, Vol 11, Iss 1, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/a844a0a9a765409e8965b903925bce31
Autor:
Lian Liu, Liying Sun, Yujun Chen, Muchuan Wang, Chenxi Yu, Yingzhao Huang, Sen Zhao, Huakang Du, Shaoke Chen, Xin Fan, Wen Tian, Zhihong Wu, Deciphering Disorders Involving Scoliosis and COmorbidities (DISCO) study group, Guixing Qiu, Terry Jianguo Zhang, Nan Wu
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-9 (2022)
Abstract Background Skeletal deformity is characterized by an abnormal anatomical structure of bone and cartilage. In our previous studies, we have found that a substantial proportion of patients with skeletal deformity could be explained by monogeni
Externí odkaz:
https://doaj.org/article/10847cd3fdaa467197acb54b9ee82b40
Autor:
Sen Zhao, Yuanqiang Zhang, Sigrun Hallgrimsdottir, Yuzhi Zuo, Xiaoxin Li, Dominyka Batkovskyte, Sen Liu, Hillevi Lindelöf, Shengru Wang, Anna Hammarsjö, Yang Yang, Yongyu Ye, Lianlei Wang, Zihui Yan, Jiachen Lin, Chenxi Yu, Zefu Chen, Yuchen Niu, Huizi Wang, Zhi Zhao, Pengfei Liu, Guixing Qiu, Jennifer E. Posey, Zhihong Wu, James R. Lupski, Ieva Micule, Britt-Marie Anderlid, Ulrika Voss, Dennis Sulander, Ekaterina Kuchinskaya, Ann Nordgren, Ola Nilsson, Deciphering Disorders Involving Scoliosis and COmorbidities (DISCO) study, Terry Jianguo Zhang, Giedre Grigelioniene, Nan Wu
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-11 (2022)
Abstract Pathogenic variants in MYH3 cause distal arthrogryposis type 2A and type 2B3 as well as contractures, pterygia and spondylocarpotarsal fusion syndromes types 1A and 1B. These disorders are ultra-rare and their natural course and phenotypic v
Externí odkaz:
https://doaj.org/article/0de9e51627714482a09108f93d1360a8
Autor:
Volkan Okur, Zefu Chen, Liesbeth Vossaert, Sandra Peacock, Jill Rosenfeld, Lina Zhao, Haowei Du, Emily Calamaro, Amanda Gerard, Sen Zhao, Jill Kelsay, Ashley Lahr, Chloe Mighton, Hillary M. Porter, Amy Siemon, Josh Silver, Shayna Svihovec, Chin-To Fong, Christina L. Grant, Jordan Lerner-Ellis, Kandamurugu Manickam, Suneeta Madan-Khetarpal, Shawn E. McCandless, Chantal F. Morel, G. Bradley Schaefer, Elizabeth M. Berry-Kravis, Ryan Gates, Natalia Gomez-Ospina, Guixing Qiu, Terry Jianguo Zhang, Zhihong Wu, Linyan Meng, Pengfei Liu, Daryl A. Scott, James R. Lupski, Christine M. Eng, Nan Wu, Bo Yuan
Publikováno v:
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-10 (2021)
Abstract The histone H3 variant H3.3, encoded by two genes H3-3A and H3-3B, can replace canonical isoforms H3.1 and H3.2. H3.3 is important in chromatin compaction, early embryonic development, and lineage commitment. The role of H3.3 in somatic canc
Externí odkaz:
https://doaj.org/article/29cca276969242bdad121202e7d7f164
Publikováno v:
Intelligent Medicine, Vol 1, Iss 3, Pp 128-133 (2021)
Developments in genetics and genomics are progressing at an unprecedented speed. Twenty years ago, the human genome project provided the first glimpses into the human genome sequence and launched a new era of human genetics. The emerging of next-gene
Externí odkaz:
https://doaj.org/article/b65a21bebae54edcb3fd5209a0338142
Autor:
Liying Sun, Yingzhao Huang, Sen Zhao, Junhui Zhao, Zihui Yan, Yang Guo, Mao Lin, Wenyao Zhong, Yuehan Yin, Zefu Chen, Nan Zhang, Yuanqiang Zhang, Zongxuan Zhao, Qingyang Li, Lianlei Wang, Xiying Dong, Yaqi Li, Xiaoxin Li, Guixing Qiu, Terry Jianguo Zhang, Zhihong Wu, Wen Tian, Nan Wu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 24, Iss , Pp 961-970 (2021)
Congenital limb malformations (CLMs) affect 1 in 500 live births. However, the value of exome sequencing (ES) for CLM is lacking. The purpose of this study was to decipher the mutational signature of CLM on an exome level. We enrolled a cohort of 66
Externí odkaz:
https://doaj.org/article/17f87b72e2f24cc3bb479e7ddcc1d2c8