Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Terry J Shackleford"'
Autor:
Terry J. Shackleford, Seethalakshmi Hariharan, Angelina V. Vaseva, Karina Alagoa, Maricruz Espinoza, Hemant K. Bid, Fuyang Li, Haihong Zhong, Doris A. Phelps, Ryan D. Roberts, Hakan Cam, Cheryl A. London, Denis C. Guttridge, Yidong Chen, Manjeet Rao, Yuzuru Shiio, Peter J. Houghton
Publikováno v:
Molecular Cancer Therapeutics. 22:539-550
Antibodies targeting insulin-like growth factor 1 receptor (IGF-1R) induce objective responses in only 5% to 15% of children with sarcoma. Understanding the mechanisms of resistance may identify combination therapies that optimize efficacy of IGF-1R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc1a9c642cb58054bfc64c2b503e27f7
https://doi.org/10.1158/1535-7163.mct-20-0625
https://doi.org/10.1158/1535-7163.mct-20-0625
Autor:
Peter J. Houghton, Yuzuru Shiio, Manjeet Rao, Yidong Chen, Denis C. Guttridge, Cheryl A. London, Hakan Cam, Ryan D. Roberts, Doris A. Phelps, Haihong Zhong, Fuyang Li, Hemant K. Bid, Maricruz Espinoza, Karina Alagoa, Angelina V. Vaseva, Seethalakshmi Hariharan, Terry J. Shackleford
Supplemental data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d321c73b0c1dff621814f82b8502466
https://doi.org/10.1158/1535-7163.22551828
https://doi.org/10.1158/1535-7163.22551828
Autor:
Wendy Demark-Wahnefried, Bharat B. Aggarwal, Ajaikumar B. Kunnumakkara, Mark Dewhirst, Shaoyu Yan, Mack T. Ruffin, Denise C. Snyder, Thomas J. Polascik, Robin T. Vollmer, Pierre Saintigny, Melanie Wergin, Kim-Anh Do, Suk-Young Yoo, Hai T. Tran, Terry J. Shackleford, John V. Heymach
Diet, nutritional status, and certain dietary supplements are postulated to influence the development and progression of prostate cancer. Angiogenesis and inflammation are central to tumor growth and progression, but the effect of diet on these proce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07c31efa750e5e271e586b6ea905e8de
https://doi.org/10.1158/1940-6207.c.6545268.v1
https://doi.org/10.1158/1940-6207.c.6545268.v1
Autor:
Angelina V. Vaseva, Peter J. Houghton, Kris C. Wood, Myron S. Ignatius, William D. Figg, Cody J. Peer, Sara M. Zimmerman, Anna T. Rogojina, Yidong Chen, Kunal Baxi, Long Wang, Terry J. Shackleford, Craig M. Goodwin, Marielle E. Yohe, Vanessa Del Pozo, Natalia Garcia
Oncogenic RAS signaling is an attractive target for fusion-negative rhabdomyosarcoma (FN-RMS). Our study validates the role of the ERK MAPK effector pathway in mediating RAS dependency in a panel of H/NRASQ61X mutant RMS cells and correlates in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41f8284cff2d8a98fdac0344310698ee
https://doi.org/10.1158/1535-7163.c.6543340
https://doi.org/10.1158/1535-7163.c.6543340
Autor:
Peter J. Houghton, Yuzuru Shiio, Manjeet Rao, Yidong Chen, Denis C. Guttridge, Cheryl A. London, Hakan Cam, Ryan D. Roberts, Doris A. Phelps, Haihong Zhong, Fuyang Li, Hemant K. Bid, Maricruz Espinoza, Karina Alagoa, Angelina V. Vaseva, Seethalakshmi Hariharan, Terry J. Shackleford
Antibodies targeting insulin-like growth factor 1 receptor (IGF-1R) induce objective responses in only 5% to 15% of children with sarcoma. Understanding the mechanisms of resistance may identify combination therapies that optimize efficacy of IGF-1R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1804d9a552368da113b80c4dfbd4aafd
https://doi.org/10.1158/1535-7163.c.6534783.v1
https://doi.org/10.1158/1535-7163.c.6534783.v1
Autor:
Wendy Demark-Wahnefried, Bharat B. Aggarwal, Ajaikumar B. Kunnumakkara, Mark Dewhirst, Shaoyu Yan, Mack T. Ruffin, Denise C. Snyder, Thomas J. Polascik, Robin T. Vollmer, Pierre Saintigny, Melanie Wergin, Kim-Anh Do, Suk-Young Yoo, Hai T. Tran, Terry J. Shackleford, John V. Heymach
PDF file - 73K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051849858e71275db41c86689ee23407
https://doi.org/10.1158/1940-6207.22526964
https://doi.org/10.1158/1940-6207.22526964
Autor:
Angelina V. Vaseva, Peter J. Houghton, Kris C. Wood, Myron S. Ignatius, William D. Figg, Cody J. Peer, Sara M. Zimmerman, Anna T. Rogojina, Yidong Chen, Kunal Baxi, Long Wang, Terry J. Shackleford, Craig M. Goodwin, Marielle E. Yohe, Vanessa Del Pozo, Natalia Garcia
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d3e61604c7ec0285e0bd4364f173cc
https://doi.org/10.1158/1535-7163.22522342
https://doi.org/10.1158/1535-7163.22522342
Autor:
Angelina V. Vaseva, Peter J. Houghton, Kris C. Wood, Myron S. Ignatius, William D. Figg, Cody J. Peer, Sara M. Zimmerman, Anna T. Rogojina, Yidong Chen, Kunal Baxi, Long Wang, Terry J. Shackleford, Craig M. Goodwin, Marielle E. Yohe, Vanessa Del Pozo, Natalia Garcia
Supplementary figures and legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a5ff6f98e44014e486437be70565a6
https://doi.org/10.1158/1535-7163.22522345.v1
https://doi.org/10.1158/1535-7163.22522345.v1
Autor:
Sara Zimmerman, Terry J Shackleford, Yi Chen, Anna T Rogojina, Kris C. Wood, Angelina V. Vaseva, Cody J. Peer, William D. Figg, Kunal Baxi, Long Wang, Natalia Garcia, Myron S. Ignatius, Craig M. Goodwin, Vanessa Del Pozo, Peter J. Houghton, Marielle E. Yohe
Publikováno v:
Molecular Cancer Therapeutics. 21:170-183
Oncogenic RAS signaling is an attractive target for fusion-negative rhabdomyosarcoma (FN-RMS). Our study validates the role of the ERK MAPK effector pathway in mediating RAS dependency in a panel of H/NRASQ61X mutant RMS cells and correlates in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::473927580cc24e9cdc412c6bd6a92d2f
https://doi.org/10.1158/1535-7163.mct-21-0194
https://doi.org/10.1158/1535-7163.mct-21-0194
Autor:
Louis Stancato, Philip J. Ebert, Yue Webster, Alle B VanWye, Robert S. Flack, Xueqian Gong, Sean Buchanan, Caitlin D. Lowery, Jack A. Dempsey, Terry J Shackleford, Michele Dowless, Jennifer R. Stephens, Jonathan B. Olsen, Peter J. Houghton, Matthew Renschler, Philip W. Iversen, Wayne Blosser, Simone Gupta, Julie Stewart
Publikováno v:
Clinical Cancer Research. 24:6028-6039
Purpose: Ewing sarcoma (ES) is a rare and highly malignant cancer that occurs in the bone and surrounding tissue of children and adolescents. The EWS/ETS fusion transcription factor that drives ES pathobiology was previously demonstrated to modulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d9c823c72453170d255553219208e8
https://doi.org/10.1158/1078-0432.ccr-18-1256
https://doi.org/10.1158/1078-0432.ccr-18-1256