Assessment of disability and disease burden in neuromyelitis optica spectrum disorders in the CIRCLES Cohort

Autor: Shervin Gholizadeh, Alex Exuzides, Jennifer Sinnott, Chella Palmer, Michael Waltz, John W. Rose, Anna Marie Jolley, Jacinta M. Behne, Megan K. Behne, Terrence F. Blaschke, Terry J. Smith, Katelyn E. Lewis, Lawrence J. Cook, Michael R. Yeaman, on behalf of The Guthy-Jackson Charitable Foundation CIRCLES Study Group

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)

Abstract Neuromyelitis optica spectrum disorders (NMOSD) comprise autoimmune diseases imposing substantial disability. We compared an NMOSD-targeted disability assessment of mobility, vision, and self-care domains (individually and composite) with th

Externí odkaz: https://doaj.org/article/6a73c333f1f04c57b141f72a255f1f1c

Rapid culture‐independent loop‐mediated isothermal amplification detection of antimicrobial resistance markers from environmental water samples

Autor: Marwa M. Hassan, Arnoud H. M. vanVliet, Owen Higgins, Liam P. Burke, Alexandra Chueiri, Louise O'Connor, Dearbháile Morris, Terry J. Smith, Roberto M. La Ragione

Publikováno v: Microbial Biotechnology, Vol 16, Iss 5, Pp 977-989 (2023)

Abstract Environmental water is considered one of the main vehicles for the transmission of antimicrobial resistance (AMR), posing an increasing threat to humans and animals health. Continuous efforts are being made to eliminate AMR; however, the det

Externí odkaz: https://doaj.org/article/896ff65799f64d7eab991536d3eb958c

Portable Differential Detection of CTX-M ESBL Gene Variants, blaCTX-M-1 and blaCTX-M-15, from Escherichia coli Isolates and Animal Fecal Samples Using Loop-Primer Endonuclease Cleavage Loop-Mediated Isothermal Amplification

Autor: Owen Higgins, Alexandra Chueiri, Louise O'Connor, Sinéad Lahiff, Liam Burke, Dearbhaile Morris, Nicola Maria Pfeifer, Belén González Santamarina, Christian Berens, Christian Menge, Manuela Caniça, Vera Manageiro, Veljo Kisand, Marwa M. Hassan, Brian Gardner, Arnoud H. M. van Vliet, Roberto M. La Ragione, Bruno Gonzalez-Zorn, Terry J. Smith

Publikováno v: Microbiology Spectrum, Vol 11, Iss 1 (2023)

ABSTRACT Cefotaximase-Munich (CTX-M) extended-spectrum beta-lactamase (ESBL) enzymes produced by Enterobacteriaceae confer resistance to clinically relevant third-generation cephalosporins. CTX-M group 1 variants, CTX-M-1 and CTX-M-15, are the leadin

Externí odkaz: https://doaj.org/article/a7b4d5be508d49fa98f657adbf9bddd6

Teprotumumab as a Novel Therapy for Thyroid-Associated Ophthalmopathy

Autor: Terry J. Smith

Publikováno v: Frontiers in Endocrinology, Vol 11 (2020)

Thyroid-associated ophthalmopathy (TAO) has remained a vexing and poorly managed autoimmune component of Graves’ disease where the tissues surrounding the eye and in the upper face become inflamed and undergo remodeling. This leads to substantial f

Externí odkaz: https://doaj.org/article/dcbc528d34a8485bafd74b5bc7d16d76

Pediatric NMOSD: A Review and Position Statement on Approach to Work-Up and Diagnosis

Autor: Silvia Tenembaum, E. Ann Yeh, The Guthy-Jackson Foundation International Clinical Consortium (GJCF-ICC), Hesham Abboud, Raed Alroughani, Ayse Altintas, Lilyana Amezcua, Metha Apiwattanakul, Nasrin Asgari, Brenda Banwell, Jeffrey Bennett, Denis Bichuetti, Terrence F. Blaschke, James Bowen, Alexey Boyko, Alexander Brandt, Simon Broadley, Wolfgang Brück, Edgar Carnero Contentti, Robert Carruthers, Tanuja Chitnis, Jeffrey Cohen, Guillermo Delgado-García,, Irena Dujmovic Basuroski, Nikos Evangelou, Kazuo Fujihara, Andrew Goodman, Benjamin Greenberg, May Han, Joachim Havla, Kerstin Hellwig, Jyh Yung Hor, Raffaele Iorio, Anu Jacob, Sven Jarius, Jorge Andres Jimenez Arango, Ilana Katz Sand, Kim Ho Jin, Kim Sung Min, Dorlan Kimbrough, Najib Kissani, Eric Klawiter, Ingo Kleiter, Marco Lana-Peixoto, Maria Isabel Leite, Michael Levy, Yaou Liu, Fred Lublin, Youssoufa Maiga, Yang Mao-Draayer, Romain Marignier, Sara Mariotto, Marcelo Matiello, Esther Melamed, Callene Momtazee, Ichiro Nakashima, Jayne Ness, Celia Oreja-Guevara, Jacqueline Palace, Lekha Pandit, Friedemann Paul, Sarah Planchon Pope, Pröbstel Anne-Katrin, Peiqing Qian, Chao Quan, Pavle Repovic, Claire Riley, Marius Ringelstein, Dalia Rotstein, Charité Klemens Ruprecht, Sá Maria José, Albert Saiz, Douglas Sato, Eslam Shosha, Nancy Sicotte, Sasitorn Siritho, Aksel Siva, Terry J. Smith, de Castillo Ibis Soto, Silva Tenembaum, Leticia Tornes, Pablo Villoslada, Dean Wingerchuk, Jens Wüfel, Bassem Yamout, Michael R. Yeaman, Scott Zamvil

Publikováno v: Frontiers in Pediatrics, Vol 8 (2020)

Neuromyelitis Optica Spectrum Disorder (NMOSD) is an inflammatory demyelinating disease of the central nervous system (CNS) primarily affecting the optic nerves and spinal cord, but also involving other regions of the CNS including the area postrema,

Externí odkaz: https://doaj.org/article/7184cbf2b4c54c13a5376db0a1799c9b