Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Terry H, Wu"'
Autor:
Roberto De Pascalis, Varunika Bhargava, Scott Espich, Terry H. Wu, H. Carl Gelhaus, Karen L. Elkins
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Identifying suitable animal models and standardizing preclinical methods are important for the generation, characterization, and development of new vaccines, including those against Francisella tularensis. Non-human primates represent an important an
Externí odkaz:
https://doaj.org/article/4726494384c1437eadcf0523c2e454f5
Autor:
Roberto De Pascalis, Blake Frey, Helen M. Rice, Varunika Bhargava, Terry H. Wu, Ross L. Peterson, J. Wayne Conlan, Anders Sjöstedt, Karen L. Elkins
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-14 (2022)
Abstract Francisella tularensis, the causative agent of tularemia, is classified as Tier 1 Select Agent with bioterrorism potential. The efficacy of the only available vaccine, LVS, is uncertain and it is not licensed in the U.S. Previously, by using
Externí odkaz:
https://doaj.org/article/45867fd5b2b64f7ea1f1656039948dd5
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionHuman pulmonary infection with non-tuberculous mycobacteria (NTM) such as Mycobacterium abscessus (Mabs) occurs in seemingly immunocompetent patients with underlying structural lung disease such as bronchiectasis in which normal ciliary f
Externí odkaz:
https://doaj.org/article/efdf50e2ad604790a3d27b3f0dbddfc8
Autor:
Julie A. Lovchik, Douglas S. Reed, Julie A. Hutt, Fangfang Xia, Rick L. Stevens, Thero Modise, Eileen M. Barry, Terry H. Wu
Publikováno v:
Pathogens, Vol 10, Iss 6, p 638 (2021)
Pneumonic tularemia is a highly debilitating and potentially fatal disease caused by inhalation of Francisella tularensis. Most of our current understanding of its pathogenesis is based on the highly virulent F. tularensis subsp. tularensis strain SC
Externí odkaz:
https://doaj.org/article/45039f8834454e4e9edf589360e43c07
Autor:
Roberto De Pascalis, Andrew Hahn, Helen M Brook, Patrik Ryden, Nathaniel Donart, Lara Mittereder, Blake Frey, Terry H Wu, Karen L Elkins
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0198140 (2018)
There are no defined correlates of protection for any intracellular pathogen, including the bacterium Francisella tularensis, which causes tularemia. Evaluating vaccine efficacy against sporadic diseases like tularemia using field trials is problemat
Externí odkaz:
https://doaj.org/article/ca1e6c3957f348d9b85a34749eae8b6e
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
Pathogenic Burkholderia rely on host factors for efficient intracellular replication and are highly refractory to antibiotic treatment. To identify host genes that are required by Burkholderia spp. during infection, we performed a RNA interference (R
Externí odkaz:
https://doaj.org/article/8416afed8be0450fa35f9a4feafb6144
Autor:
Terry H. Wu, Carl Gelhaus, Igor Golovliov, Helena Lindgren, Anders Sjöstedt, Kjell Eneslätt, Patrik Rydén
Publikováno v:
Pathogens
Volume 9
Issue 5
Pathogens, Vol 9, Iss 338, p 338 (2020)
Volume 9
Issue 5
Pathogens, Vol 9, Iss 338, p 338 (2020)
Francisella tularensis causes the severe disease tularemia. In the present study, the aim was to identify correlates of protection in the rat co-culture model by investigating the immune responses using two vaccine candidates conferring distinct degr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf25b9eb7779e931af379b62860219f9
Autor:
Jens Langsjoen, Ivy Foo-Hurwitz, Chris Bartlett, Douglas J Perkins, Hannah Wilcox, Steven B. Bradfute, Phil Seidenberg, Qiuying Cheng, Steven Villescas, Myissa Weiss, Timothy B Muller, Terry H Wu
Publikováno v:
Experimental Biology and Medicine
Coronavirus disease 2019 (COVID-19) is an illness caused by a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The disease was first identified as a cluster of respiratory illness in Wuhan City, Hubei Province, China,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c27cf020bf77b190e7301b7dc38eb62
Autor:
Heather J Ray, Ping Chu, Terry H Wu, C Rick Lyons, Ashlesh K Murthy, M Neal Guentzel, Karl E Klose, Bernard P Arulanandam
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e9952 (2010)
The pathogenesis of Francisella tularensis, the causative agent of tularemia, has been primarily characterized in mice. However, the high degree of sensitivity of mice to bacterial challenge, especially with the human virulent strains of F. tularensi
Externí odkaz:
https://doaj.org/article/e8e3aa69be004e0fa4caa812a79ed972
Autor:
Rick Stevens, Fangfang Xia, Julie A. Hutt, Thero Modise, Eileen M. Barry, Julie A. Lovchik, Terry H. Wu, Douglas S. Reed
Publikováno v:
Pathogens
Volume 10
Issue 6
Pathogens, Vol 10, Iss 638, p 638 (2021)
Volume 10
Issue 6
Pathogens, Vol 10, Iss 638, p 638 (2021)
Pneumonic tularemia is a highly debilitating and potentially fatal disease caused by inhalation of Francisella tularensis. Most of our current understanding of its pathogenesis is based on the highly virulent F. tularensis subsp. tularensis strain SC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baa71299cab381e0e0308b470316aa17
https://doi.org/10.3390/pathogens10060638
https://doi.org/10.3390/pathogens10060638