Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Terry G. Wilkinson"'
Autor:
Randall C. Mazzarino, Veronika Baresova, Marie Zikánová, Nathan Duval, Terry G. Wilkinson, II, David Patterson, Guido N. Vacano
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 25, Iss , Pp 100642- (2020)
In de novo purine biosynthesis (DNPS), 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase (EC 2.1.2.3)/inosine monophosphate cyclohydrolase (EC 3.5.4.10) (ATIC) catalyzes the last two reactions of the pathway: conversion of 5-aminoimidaz
Externí odkaz:
https://doaj.org/article/9d371210153f41a2a86d1a26c04d6739
Autor:
Randall C. Mazzarino, Veronika Baresova, Marie Zikánová, Nathan Duval, Terry G. Wilkinson, II, David Patterson, Guido N. Vacano
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 21, Iss , Pp - (2019)
Adenylosuccinate lyase (ADSL) catalyzes two steps in de novo purine synthesis (DNPS). Mutations in ADSL can result in inborn errors of metabolism characterized by developmental delay and disorder phenotypes, with no effective treatment options. Recen
Externí odkaz:
https://doaj.org/article/888860c192834a11b698b87f3b09b951
Autor:
Vita Stepanova, Kaja Ewa Moczulska, Guido N Vacano, Ilia Kurochkin, Xiangchun Ju, Stephan Riesenberg, Dominik Macak, Tomislav Maricic, Linda Dombrowski, Maria Schörnig, Konstantinos Anastassiadis, Oliver Baker, Ronald Naumann, Ekaterina Khrameeva, Anna Vanushkina, Elena Stekolshchikova, Alina Egorova, Anna Tkachev, Randall Mazzarino, Nathan Duval, Dmitri Zubkov, Patrick Giavalisco, Terry G Wilkinson, David Patterson, Philipp Khaitovich, Svante Pääbo
Publikováno v:
eLife, Vol 10 (2021)
We analyze the metabolomes of humans, chimpanzees, and macaques in muscle, kidney and three different regions of the brain. Although several compounds in amino acid metabolism occur at either higher or lower concentrations in humans than in the other
Externí odkaz:
https://doaj.org/article/fd1a3282c2934c4483b85c46f214b2b5
Autor:
Randall C. Mazzarino, Veronika Baresova, Guido N. Vacano, Marie Zikanova, Terry G. Wilkinson, Nathan Duval, David Patterson
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0247227 (2021)
PLoS ONE, Vol 16, Iss 7, p e0247227 (2021)
In humans, GART [phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) / phosphoribosylglycinamide synthetase (EC 6.3.4.13) / phosphoribosylaminoimidazole synthetase (EC 6.3.3.1)] is a trifunctional protein which catalyzes the second, third, and f
Autor:
Ilia Kurochkin, Anna Tkachev, Vita Stepanova, Ekaterina Khrameeva, David Patterson, Svante Pääbo, Oliver Baker, Nathan Duval, Linda Dombrowski, Stephan Riesenberg, Guido N. Vacano, Terry G. Wilkinson, Ronald Naumann, Elena Stekolshchikova, Dmitri Zubkov, Kaja Ewa Moczulska, Maria Schörnig, Xiangchun Ju, Anna Vanushkina, Philipp Khaitovich, Randall C. Mazzarino, Tomislav Maricic, Patrick Giavalisco, Dominik Macak, Konstantinos Anastassiadis, Alina Egorova
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7042b30ed9c19c778a1b4f97e24e9589
https://doi.org/10.7554/elife.58741.sa2
https://doi.org/10.7554/elife.58741.sa2
Autor:
Svante Pääbo, Philipp Khaitovich, Dominik Macak, Nathan Duval, Stephan Riesenberg, Guido N. Vacano, Terry G. Wilkinson, Maria Schörnig, Dmitri Zubkov, Xiangchun Ju, Ronald Naumann, Oliver Baker, Ilia Kurochkin, Randall C. Mazzarino, Ekaterina Khrameeva, Anna Vanyushkina, Linda Dombrowski, Patrick Giavalisco, Elena Stekolschikova, Konstantinos Anastassiadis, Kaja Ewa Moczulska, Vita V. Stepanova, David Patterson, Tomislav Maricic
We analyze the metabolomes of humans, chimpanzees and macaques in muscle, kidney and three different regions of the brain. Whereas several compounds in amino acid metabolism occur at either higher or lower concentrations in humans than in the other p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd3ede6407f756aed3013f8da3e125c7
https://doi.org/10.1101/2020.05.11.087338
https://doi.org/10.1101/2020.05.11.087338
Autor:
Terry G. Wilkinson, Veronika Baresova, Randall C. Mazzarino, Guido N. Vacano, David Patterson, Marie Zikanova, Nathan Duval
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 21, Iss, Pp-(2019)
Molecular Genetics and Metabolism Reports
Molecular Genetics and Metabolism Reports
Adenylosuccinate lyase (ADSL) catalyzes two steps in de novo purine synthesis (DNPS). Mutations in ADSL can result in inborn errors of metabolism characterized by developmental delay and disorder phenotypes, with no effective treatment options. Recen
Autor:
Elena Stekolshchikova, Randall C. Mazzarino, Anna Vanushkina, Maria Schörnig, Guido N. Vacano, Oliver Baker, Anna Tkachev, Philipp Khaitovich, Dominik Macak, Svante Pääbo, David Patterson, Konstantinos Anastassiadis, Linda Dombrowski, Tomislav Maricic, Vita Stepanova, Stephan Riesenberg, Dmitri Zubkov, Ilia Kurochkin, Terry G. Wilkinson, Patrick Giavalisco, Xiangchun Ju, Ronald Naumann, Nathan Duval, Ekaterina Khrameeva, Kaja Ewa Moczulska, Alina Egorova
Publikováno v:
eLife
Elife
eLife, Vol 10 (2021)
Elife
eLife, Vol 10 (2021)
We analyze the metabolomes of humans, chimpanzees, and macaques in muscle, kidney and three different regions of the brain. Although several compounds in amino acid metabolism occur at either higher or lower concentrations in humans than in the other
Autor:
Nathan Duval, Stephen P. Ray, Kingshuk Ghosh, Terry G. Wilkinson, David Patterson, Sean E. Shaheen
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1834:1545-1553
Adenylosuccinate lyase (ADSL) is a homotetrameric enzyme involved in the de novo purine biosynthesis pathway and purine nucleotide cycle. Missense mutations in the protein lead to ADSL deficiency, an inborn error of purine metabolism characterized by
Autor:
Stanislav Kmoch, Nathan Duval, Marie Zikanova, Vaclava Skopova, Veronika Baresova, Terry G. Wilkinson, Guido N. Vacano, David Patterson, Kyleen Luhrs
Publikováno v:
Molecular Genetics and Metabolism. 108:178-189
Purines are molecules essential for many cell processes, including RNA and DNA synthesis, regulation of enzyme activity, protein synthesis and function, energy metabolism and transfer, essential coenzyme function, and cell signaling. Purines are prod