Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Terry D. Hinds"'
Autor:
Mikala M. Zelows, Corissa Cady, Nikitha Dharanipragada, Anna E. Mead, Zachary A. Kipp, Evelyn A. Bates, Venkateshwari Varadharajan, Rakhee Banerjee, Se-Hyung Park, Nathan R. Shelman, Harrison A. Clarke, Tara R. Hawkinson, Terrymar Medina, Ramon C. Sun, Todd A. Lydic, Terry D. Hinds, Jr., J. Mark Brown, Samir Softic, Gregory A. Graf, Robert N. Helsley
Publikováno v:
Molecular Metabolism, Vol 78, Iss , Pp 101815- (2023)
Background and aims: Genome and epigenome wide association studies identified variants in carnitine palmitoyltransferase 1a (CPT1a) that associate with lipid traits. The goal of this study was to determine the role of liver-specific CPT1a on hepatic
Externí odkaz:
https://doaj.org/article/2e4f326f6761408c9020ccde9aaab299
Autor:
Jieyun Jiang, Courtney Turpin, Guofang (Shirley) Qiu, Mei Xu, Eun Lee, Terry D. Hinds Jr., Martha L. Peterson, Brett T. Spear
Publikováno v:
Hepatology Communications, Vol 6, Iss 12, Pp 3550-3562 (2022)
Abstract Liver cancer, comprised primarily of hepatocellular carcinoma (HCC), is the third leading cause of cancer deaths worldwide and increasing in Western countries. We previously identified the transcription factor zinc fingers and homeoboxes 2 (
Externí odkaz:
https://doaj.org/article/849e65001ae14f83b9b1dcb7478ed4ad
Publikováno v:
Frontiers in Sports and Active Living, Vol 4 (2023)
Exercise performance is dependent on many factors, such as muscular strength and endurance, cardiovascular capacity, liver health, and metabolic flexibility. Recent studies show that plasma levels of bilirubin, which has classically been viewed as a
Externí odkaz:
https://doaj.org/article/3835ac39877543ad929295403fae7b91
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/23828b8ed45549e98b4efd9c4aa0bc8b
Autor:
Zachary A. Kipp, Genesee J. Martinez, Evelyn A. Bates, Agil B. Maharramov, Robert M. Flight, Hunter N. B. Moseley, Andrew J. Morris, David E. Stec, Terry D. Hinds
Publikováno v:
Metabolites, Vol 13, Iss 2, p 215 (2023)
Studies have indicated that increasing plasma bilirubin levels might be useful for preventing and treating hepatic lipid accumulation that occurs with metabolic diseases such as obesity and diabetes. We have previously demonstrated that mice with hyp
Externí odkaz:
https://doaj.org/article/1cb818cd4a674e56962f0b1517095d56
Autor:
Evelyn A. Bates, Zachary A. Kipp, Genesee J. Martinez, Olufunto O. Badmus, Mangala M. Soundarapandian, Donald Foster, Mei Xu, Justin F. Creeden, Jennifer R. Greer, Andrew J. Morris, David E. Stec, Terry D. Hinds
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 252 (2023)
Several population studies have observed lower serum bilirubin levels in patients with non-alcoholic fatty liver disease (NAFLD). Yet, treatments to target this metabolic phenotype have not been explored. Therefore, we designed an N-Acetylgalactosami
Externí odkaz:
https://doaj.org/article/d673bff3a31949f9babcc166e038f8be
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 170 (2023)
Bilirubin levels in obese humans and rodents have been shown to be lower than in their lean counterparts. Some studies have proposed that the glucuronyl UGT1A1 enzyme that clears bilirubin from the blood increases in the liver with obesity. UGT1A1 cl
Externí odkaz:
https://doaj.org/article/dcd8e3fc17c74fd6b1a20786aac96bdd
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/8f5d20af90b5453ebbe9d708fc80df8b
Autor:
Apurva Lad, Jonathan Hunyadi, Jacob Connolly, Joshua D. Breidenbach, Fatimah K. Khalaf, Prabhatchandra Dube, Shungang Zhang, Andrew L. Kleinhenz, David Baliu-Rodriguez, Dragan Isailovic, Terry D. Hinds, Cara Gatto-Weis, Lauren M. Stanoszek, Thomas M. Blomquist, Deepak Malhotra, Steven T. Haller, David J. Kennedy
Publikováno v:
Antioxidants, Vol 11, Iss 8, p 1625 (2022)
We have previously shown in a murine model of Non-alcoholic Fatty Liver Disease (NAFLD) that chronic, low-dose exposure to the Harmful Algal Bloom cyanotoxin microcystin-LR (MC-LR), resulted in significant hepatotoxicity including micro-vesicular lip
Externí odkaz:
https://doaj.org/article/86730d6c10e0400c9209b5650c3fb6b5
Autor:
Terry D. Hinds, Justin F. Creeden, Darren M. Gordon, Donald F. Stec, Matthew C. Donald, David E. Stec
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
The inverse relationship of plasma bilirubin levels with liver fat accumulation has prompted the possibility of bilirubin as a therapeutic for non-alcoholic fatty liver disease. Here, we used diet-induced obese mice with non-alcoholic fatty liver dis
Externí odkaz:
https://doaj.org/article/19f5e461dc9d44678bb40bb50fab383b