Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Terry C. Yin"'
Publikováno v:
iScience, Vol 23, Iss 6, Pp 101216- (2020)
Summary: Ghrelin regulates both energy intake and glucose homeostasis. In the endocrine pancreas, ghrelin inhibits insulin release to prevent hypoglycemia during fasting. The mechanism through which this is accomplished is unclear, but recent studies
Externí odkaz:
https://doaj.org/article/220fb37e6c984249aabd0ef9d1ae0ce9
Autor:
Dollada Srisai, Terry C. Yin, Abigail A. Lee, Alix A. J. Rouault, Nicole A. Pearson, Justin L. Grobe, Julien A. Sebag
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Melanocortin receptor accessory protein 2 (MRAP2) is an adaptor protein that contributes to melanocortin-4 receptor and prokineticin receptor 1 signalling. Here the authors show that MRAP2 also regulates ghrelin receptor signalling in the hypothalamu
Externí odkaz:
https://doaj.org/article/0c8ac5f69f6445bd9e9a8456fe6f8bef
Autor:
Huxing Cui, Yuan Lu, Michael Z. Khan, Rachel M. Anderson, Latisha McDaniel, Hannah E. Wilson, Terry C. Yin, Jason J. Radley, Andrew A. Pieper, Michael Lutter
Publikováno v:
Cell Reports, Vol 11, Iss 3, Pp 344-350 (2015)
Eating disorders, such as anorexia nervosa and bulimia nervosa, are common and severe mental illnesses of unknown etiology. Recently, we identified a rare missense mutation in the transcription factor estrogen-related receptor alpha (ESRRA) that is a
Externí odkaz:
https://doaj.org/article/ff15e3a7f9534a1aab20765ab9f79b87
Autor:
Terry C. Yin, Jeremiah K. Britt, Héctor De Jesús-Cortés, Yuan Lu, Rachel M. Genova, Michael Z. Khan, Jaymie R. Voorhees, Jianqiang Shao, Aaron C. Katzman, Paula J. Huntington, Cassie Wassink, Latisha McDaniel, Elizabeth A. Newell, Laura M. Dutca, Jacinth Naidoo, Huxing Cui, Alexander G. Bassuk, Matthew M. Harper, Steven L. McKnight, Joseph M. Ready, Andrew A. Pieper
Publikováno v:
Cell Reports, Vol 8, Iss 6, Pp 1731-1740 (2014)
The P7C3 class of neuroprotective aminopropyl carbazoles has been shown to block neuronal cell death in models of neurodegeneration. We now show that P7C3 molecules additionally preserve axonal integrity after injury, before neuronal cell death occur
Externí odkaz:
https://doaj.org/article/eaf07f99280f4695b3055e2a7c8aa34d
Publikováno v:
The Journal of biological chemistry.
The regulation of energy homeostasis is a complex system involving multiple hormones, neuropeptides, and receptors. Prokineticins (PK1 and PK2) are agonists to two GPCRs, Prokineticin receptor 1 and 2 (PKR1 and PKR2), which decrease food intake when
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a578a46ac8f1fe6c7fb05b4fe8270999
https://pubmed.ncbi.nlm.nih.gov/36539034
https://pubmed.ncbi.nlm.nih.gov/36539034
Autor:
Kathryn Franke, Terry C. Yin, Josie L. Emery, Min-Kyoo Shin, Sarah Barker, Xudong Liao, Danyel R. Crosby, Yeojung Koh, Kalyani Chaubey, Rachel Schroeder, James D. Reynolds, Hisashi Fujioka, Matthew M. Harper, Mukesh K. Jain, Andrew A. Pieper, Xinmiao Tang, Matasha Dhar, Emiko Miller, Edwin Vázquez-Rosa, Coral J. Cintrón-Pérez
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Chronic neurodegeneration, a major cause of the long-term disabilities that afflict survivors of traumatic brain injury (TBI), is linked to an increased risk for late-life neurodegenerative disorders, including Alzheimer’s disease, Par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f041042dfc5a720aa0c91643b314fe
http://europepmc.org/articles/PMC7959512
http://europepmc.org/articles/PMC7959512
Autor:
Terry C. Yin, Jonathan G. Van Vranken, Dhiraj Srivastava, Jissele A. Verdinez, Aschleigh E. Graham, Susan A. Walsh, Michael A. Acevedo, Robert J. Kerns, Nikolai O. Artemyev, Steven P. Gygi, Julien Albert Sebag
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca80afd0f7b10eeb06fe17af721ce13c
https://doi.org/10.2139/ssrn.4251792
https://doi.org/10.2139/ssrn.4251792
Publikováno v:
iScience, Vol 23, Iss 6, Pp 101216-(2020)
iScience
iScience
Summary Ghrelin regulates both energy intake and glucose homeostasis. In the endocrine pancreas, ghrelin inhibits insulin release to prevent hypoglycemia during fasting. The mechanism through which this is accomplished is unclear, but recent studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a7b53a6727098dd0090aa296efa90bb
http://www.sciencedirect.com/science/article/pii/S2589004220304016
http://www.sciencedirect.com/science/article/pii/S2589004220304016
Autor:
Andrew A. Pieper, Min-Kyoo Shin, James J. Sahn, Daniel J. Liebl, Edwin Vázquez-Rosa, Stephen F. Martin, Coral J. Cintrón-Pérez, Terry C. Yin, Josie L. Emery, Michael R. Watson, Timothy R. Hodges, Rachel Schroeder
Publikováno v:
ACS Chemical Neuroscience. 10:1595-1602
Compounds targeting the sigma 2 receptor, which we recently cloned and showed to be identical with transmembrane protein 97 (σ2R/TMEM97), are broadly applicable therapeutic agents currently in clinical trials for imaging in breast cancer and for tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb994ce4bb6f644ed226e8ffc18f2e3d
https://doi.org/10.1021/acschemneuro.8b00543
https://doi.org/10.1021/acschemneuro.8b00543
Autor:
Michael Z. Khan, Andrew A. Pieper, Jaymie R. Voorhees, Latisha McDaniel, Matthew T. Remy, Daniel J. Brat, Noelle S. Williams, Eli El Rassi, Coral J. Cintrón-Pérez, Laura M. Dutca, Terry C. Yin
Publikováno v:
Biological Psychiatry. 84:488-498
BACKGROUND: In addition to cognitive deficits, Alzheimer’s disease (AD) is also associated with other neuropsychiatric symptoms, including severe depression. Indeed, depression often precedes cognitive deficits in patients with AD. Unfortunately, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1e412c94f19c20f9a8fe2ea99891f0
https://doi.org/10.1016/j.biopsych.2017.10.023
https://doi.org/10.1016/j.biopsych.2017.10.023