SARS-CoV-2 spike-ferritin-nanoparticle adjuvanted with ALFQ induces long-lived plasma cells and cross-neutralizing antibodies.

Autor: Shrivastava S; Laboratory of Adjuvant and Antigen Research, U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Carmen JM; Laboratory of Adjuvant and Antigen Research, U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Lu Z; Department of Pediatrics, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Basu S; Laboratory of Adjuvant and Antigen Research, U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Sankhala RS; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Chen WH; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Nguyen P; Laboratory of Adjuvant and Antigen Research, U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Chang WC; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA., King J; Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Corbitt C; Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Mayer S; Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Bolton JS; Malaria Biologics Branch, Walter Reed Army Institute of Research, Silver Spring, USA., Anderson A; Laboratory of Adjuvant and Antigen Research, U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Oak Ridge Institute of Science and Education, Oak Ridge, TN, 37831, USA., Swafford I; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Terriquez GD; Laboratory of Adjuvant and Antigen Research, U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Trinh HV; Laboratory of Adjuvant and Antigen Research, U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Kim J; Laboratory of Adjuvant and Antigen Research, U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Jobe O; Laboratory of Adjuvant and Antigen Research, U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Paquin-Proulx D; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Matyas GR; Laboratory of Adjuvant and Antigen Research, U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Gromowski GD; Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Currier JR; Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Bergmann-Leitner E; Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Malaria Biologics Branch, Walter Reed Army Institute of Research, Silver Spring, USA., Modjarrad K; Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Michael NL; Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Joyce MG; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Malloy AMW; Department of Pediatrics, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Rao M; Laboratory of Adjuvant and Antigen Research, U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA. mrao@hivresearch.org.; Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA. mrao@hivresearch.org.

Publikováno v: NPJ vaccines [NPJ Vaccines] 2023 Mar 18; Vol. 8 (1), pp. 43. Date of Electronic Publication: 2023 Mar 18.