Výsledky vyhledávání - "Terrie L Ulery"

Phase I study of samalizumab in chronic lymphocytic leukemia and multiple myeloma: blockade of the immune checkpoint CD200

Autor: Camille L. Bedrosian, Xiaoping Zhang, Maria Whelden, Mark C. Lanasa, Lan Li, Charles M. Farber, Terrie L Ulery, Susan J. Faas, Manjari Pandey, Anjli Kukreja, Leonard T. Heffner, Daruka Mahadevan

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-13 (2019)
Journal for Immunotherapy of Cancer

Purpose Samalizumab is a novel recombinant humanized monoclonal antibody that targets CD200, an immunoregulatory cell surface member of the immunoglobulin superfamily that dampens excessive immune responses and maintains self-tolerance. This first-in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b470ec25db3dee971cdc85765394090
https://doi.org/10.1186/s40425-019-0710-1

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The yeast IMP1 gene is allelic to GAL2

Autor: Terrie L. Ulery, David A. Mangus, J A Jaehning

Publikováno v: Molecular and General Genetics MGG. 230:129-135

We have found that many laboratory strains of yeast are defective in galactose metabolism owing to a recessive mutation in the previously characterized nuclear gene, IMP1. This defect leads to a requirement for mitochondrial function for growth on, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be5ecc35f97cdddc798a5df1e7718e2c
https://doi.org/10.1007/bf00290660

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XIII. Yeast mapping reports.MTF1, encoding the yeast mitochondrial RNA polymerase specificity factor, is located on chromosome XIII

Autor: Terrie L. Ulery, J A Jaehning

Publikováno v: Yeast. 10:839-841

MTF1 is a nuclear gene that encodes the promoter recognition factor of the yeast mitochondrial RNA polymerase. The MTF1 gene was physically mapped to chromosome XIII. Genetic mapping data indicate that the gene is closely linked to RNA1.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::064c8fff482368ac84ef14ac88d43276
https://doi.org/10.1002/yea.320100614

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Glucose repression of yeast mitochondrial transcription: kinetics of derepression and role of nuclear genes

Autor: Terrie L. Ulery, Sei Heon Jang, Judith A. Jaehning

Publikováno v: Molecular and cellular biology. 14(2)

Yeast mitochondrial transcript and gene product abundance has been observed to increase upon release from glucose repression, but the mechanism of regulation of this process has not been determined. We report a kinetic analysis of this phenomenon, wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7484741a0e5b78c34eaadb1d771c4e10
https://pubmed.ncbi.nlm.nih.gov/8289797

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First-In-Human Phase I Dose Escalation Study of a Humanized Anti-CD200 Antibody (Samalizumab) In Patients with Advanced Stage B Cell Chronic Lymphocytic Leukemia (B-CLL) or Multiple Myeloma (MM)

Autor: Daruka Mahadevan, Maria Whelden, Camille L. Bedrosian, Lan Li, Leonard T. Heffner, Mark C. Lanasa, Susan J. Faas, Anjli Kukreja, Terrie L Ulery

Publikováno v: Blood. 116:2465-2465

Abstract 2465 Background: The immunosuppressive molecule CD200 is upregulated on B-CLL and MM cells which may contribute to tumor immune evasion. Samalizumab is a novel first-in-class recombinant humanized monoclonal antibody that specifically binds

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e272cc809a4977658b027dcff961850c
https://doi.org/10.1182/blood.v116.21.2465.2465

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