Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Terri-Leigh Stephen"'
Autor:
Terri‐Leigh Stephen, Laura Korobkova, Kymry T Jones, Ryan P Cabeen, Maricarmen Pachicano, Debra Hawes, Carol A Miller, Michael S Bienkowski
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Priya Rangan, Fleur Lobo, Edoardo Parrella, Nicolas Rochette, Marco Morselli, Terri-Leigh Stephen, Anna Laura Cremonini, Luca Tagliafico, Angelica Persia, Irene Caffa, Fiammetta Monacelli, Patrizio Odetti, Tommaso Bonfiglio, Alessio Nencioni, Martina Pigliautile, Virginia Boccardi, Patrizia Mecocci, Christian J. Pike, Pinchas Cohen, Mary Jo LaDu, Matteo Pellegrini, Kyle Xia, Katelynn Tran, Brandon Ann, Dolly Chowdhury, Valter D. Longo
Publikováno v:
Cell reports, vol 40, iss 13
The effects of fasting-mimicking diet (FMD) cycles in reducing many aging and disease risk factors indicate it could affect Alzheimer's disease (AD). Here, we show that FMD cycles reduce cognitive decline and AD pathology in E4FAD and 3xTg AD mouse m
Autor:
Andrew D. Randall, Tracey K. Murray, Joshua Harvey, Zeshan Ahmed, Michael J. O'Neill, Michael Hutton, Francesco Tamagnini, Johanna Jackson, Judith Piegsa, Terri-Leigh Stephen, Alice Oliver-Evans, Katherine Sung
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Alzheimer’s disease (AD)-associated synaptic dysfunction drives the progression of pathology from its earliest stages. Amyloid β (Aβ) species, both soluble and in plaque deposits, have been causally related to the progressive, structural and func
Autor:
Mafalda Cacciottolo, Caleb E. Finch, Mary Jo LaDu, Terri-Leigh Stephen, Christian J. Pike, Todd E. Morgan, Deebika Balu
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-11 (2019)
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-11 (2019)
Microglia affect Alzheimer’s disease (AD) pathogenesis in opposing manners, by protecting against amyloid accumulation in early phases of the disease and promoting neuropathology in advanced stages. Recent research has identified specific microglia
Autor:
Alice Oliver-Evans, Michael Hutton, Francesco Tamagnini, Terri-Leigh Stephen, Andrew D. Randall, Soraya Meftah, Michael C. Ashby, Johanna Jackson, James D. Johnson, Zeshan Ahmed, Michael J. O'Neill, John T.R. Isaac
Publikováno v:
Alzheimer's & Dementia. 13
Autor:
Susan Shirley Black, Akiko Rasmussen, Tim Rasmussen, Samantha Miller, Michelle D. Edwards, Ian R. Booth, Neil R. Stokes, Terri-Leigh Stephen
Publikováno v:
Channels
Mechanosensitive channels sense elevated membrane tension that arises from rapid water influx occurring when cells move from high to low osmolarity environments (hypoosmotic shock). These non-specific channels in the cytoplasmic membrane release osmo
Autor:
Terri-Leigh, Stephen, Nathalie F, Higgs, David F, Sheehan, Sana, Al Awabdh, Guillermo, López-Doménech, I Lorena, Arancibia-Carcamo, Josef T, Kittler
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 35(48)
It is fast emerging that maintaining mitochondrial function is important for regulating astrocyte function, although the specific mechanisms that govern astrocyte mitochondrial trafficking and positioning remain poorly understood. The mitochondrial R
Publikováno v:
Biochemical Society transactions. 42(5)
Astrocytes exhibit cellular excitability through variations in their intracellular calcium (Ca²⁺) levels in response to synaptic activity. Astrocyte Ca²⁺ elevations can trigger the release of neuroactive substances that can modulate synaptic tr