Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Terri F. Swearengin"'
Autor:
D. GAYLE DEBORD, KENNETH L. CHEEVER, DWIGHT M. WERREN, THOMAS M. REID, TERRI F. SWEARENGIN, RUSSELL E. SAVAGE
Publikováno v:
Toxicological Sciences. 30:138-144
Publikováno v:
Fundamental and Applied Toxicology. 18:522-531
Hemoglobin (Hb) and albumin (Alb) adducts of the suspect human carcinogen ortho-toluidine (OT) were quantified in blood samples collected from rats after a single i.p. injection. Mild alkaline hydrolysis of Hb adducted with [14C]OT followed by extrac
Publikováno v:
Toxicological Sciences. 18:522-531
Autor:
Kenneth L. Cheever, Russell E. Savage, Donald E. Richards, Terri F. Swearengin, Walter W. Weigel, D. Gayle DeBord, Karen B. Begley
Publikováno v:
Fundamental and Applied Toxicology. 14:273-283
The macromolecular binding of 4,4'-methylenebis(2-chloroaniline) (MOCA), a suspect human carcinogen, was studied in the adult male Sprague-Dawley rat after both oral and dermal administration. Rats were euthanized 1, 3, 7, 10, 14, and 29 days after a
Autor:
KENNETH L. CHEEVER, DONALD E. RICHARDS, WALTER W. WEIGEL, KAREN B. BEGLEY, D. GAYLE DEBORD, TERRI F. SWEARENGIN, RUSSELL E. SAVAGE
Publikováno v:
Toxicological Sciences. 14:273-283
Autor:
Terri F. Swearengin, Thomas M. Reid, Dwight Werren, Kenneth L. Cheever, Russell E. Savage, D. Gayle DeBord
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 30(1)
The probable human carcinogen 4,4'-methylene-bis(2-chloroaniline) (MOCA) was utilized to develop biomarkers of exposure to occupational carcinogens. The 32P postlabeling assay, utilizing the nuclease P1 enhancement procedure, was used to evaluate MOC
Publikováno v:
Archives of toxicology. 66(4)
The binding characteristics of [14C]ortho-toluidine (OT), a suspect human carcinogen, were investigated in male Sprague-Dawley rats. Rats were administered [14C]OT i.p. at 10, 20, 40, 50, or 100 mg/kg body weight, then sacrificed at 2, 4, 8, 18, 24,
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 16(1)
The effect of multiple oral administration of MOCA, a suspect human carcinogen, was studied in the adult male rat. As many as 28 consecutive daily doses of [14C]MOCA at 28.1 mumol/kg body wt (5 microCi/day) were administered and rats were euthanized