Výsledky vyhledávání - "Terri Daniels"

A novel monoclonal antibody specific for the N-terminal end of GAD65

Autor: Terri Daniels, Santica M. Marcovina, Åke Lernmark, Lisa P. Hammerle, Per Lundgren, Christiane S. Hampe

Publikováno v: Journal of Neuroimmunology. 113:63-71

We describe a novel monoclonal antibody raised towards the N-terminus of the 65 kDa isoform of glutamate decarboxylase (GAD65). This N-GAD65 mAb is highly specific for GAD65 and can be used in a wide range of applications such as Western blot analysi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac812785b1f9f93837cb72c7c6a4186
https://doi.org/10.1016/s0165-5728(00)00423-9

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Epitope-specific glutamic acid decarboxylase-65 autoantibodies in intravenous immunoglobulin preparations

Autor: Connie L. Davis, Åke Lernmark, Wei Hao, Christiane S. Hampe, Terri Daniels

Publikováno v: Transfusion Medicine. 9:307-310

Intravenous immunoglobulin (IVIG) has been used to treat many autoimmune disorders including Stiff-Man Syndrome (SMS). SMS is a neurological disorder associated with an immune-mediated deficiency of gamma-aminobutyric acid (GABA) due to autoantibodie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac43a33087ae65eb1008b7fb95fe9292
https://doi.org/10.1046/j.1365-3148.1999.00214.x

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Plasmapheresis and immunosuppression in stiff-man syndrome with type 1 diabetes: a 2-year study

Autor: Irl B. Hirsch, Åke Lernmark, Daniel Walsh, Connie L. Davis, Terri Daniels, Lily J. Eng, Wei Hao

Publikováno v: Journal of Neurology. 246:731-735

Key words Stiff-man syndrome · Type 1 diabetes · GAD65 autoantibodies · Plasmapheresis · ImmunosuppressionSirs: Stiff-man syndrome (SMS) is arare neurological disorder character-ized by involuntary fluctuating stiff-ness and rigidity of axial ske

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ccc09fd259b6f34f421ec20515c805b1
https://doi.org/10.1007/s004150050443

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A novel radioligand binding assay to determine diagnostic accuracy of isoform-specific glutamic acid decarboxylase antibodies in childhood IDDM

Autor: A E Karlsen, W. A. Hagopian, B. Michelsen, Catherine E. Grubin, Åke Lernmark, Linsong Li, Esper Boel, Terri Daniels, Mona Landin-Olsson, Bert Toivola

Publikováno v: Diabetologia. 37:344-350

Insulin-dependent diabetes mellitus (IDDM) is associated with autoreactivity against GAD but the diagnostic sensitivity (positivity in disease) and specificity (negativity in health) of isoform-specific GAD antibodies have yet to be defined in assay

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9afdbb24eaf8f8f29c3685ee22aa242e
https://doi.org/10.1007/bf00408469

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Age-dependent loss of tolerance to an immunodominant epitope of glutamic acid decarboxylase in diabetic-prone RIP-B7/DR4 mice

Autor: Li Wen, Kouichi Ito, Terri Daniels, Åke Lernmark, Ben A. Falk, Kellee A. Unrath, Gerald T. Nepom, John A. Gebe

Publikováno v: Clinical immunology (Orlando, Fla.). 121(3)

We have identified for the first time an age-dependent spontaneous loss of tolerance to two self-antigenic epitopes derived from putative diabetes-associated antigens glutamic acid decarboxylase (GAD65) and glial fibrillary acidic protein (GFAP) in R

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c547d9b6334b8da0eab9e44da2506538
https://pubmed.ncbi.nlm.nih.gov/16979383

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Conformation-dependent GAD65 autoantibodies in diabetes

Autor: Olov Rolandsson, Christiane S. Hampe, Carla J. Greenbaum, Dong Luo, Lisa K. Gilliam, Terri Daniels, Santica M. Marcovina, Åke Lernmark, Wiltrud Richter, Ingrid Kockum, Lynn M. Bekris, Mona Landin-Olsson

Publikováno v: Diabetologia. 47(9)

Aims/hypothesis. Conformation-dependent autoantibodies directed against GAD65 are markers of Type 1 diabetes. In this study we aimed to determine whether the substitution of GAD65 with GAD67 amino acids would affect the binding of conformation-depend

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6609aa7992b8c3f4e76d3a56dc3e8de
https://pubmed.ncbi.nlm.nih.gov/15365614

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Diagnostic sensitivity of immunodominant epitopes of glutamic acid decarboxylase (GAD65) autoantibodies in childhood IDDM

Autor: M Ackefors, John A. Robertson, C Carlberg, Alberto Falorni, Bengt Persson, Åke Lernmark, Terri Daniels

The prevalence and titre of epitope-specific autoantibodies to glutamic acid decarboxylase (GAD65) in 155 insulin-dependent diabetic (IDDM) and 9 GAD65 antibody (Ab)-positive healthy children were determined using four GAD65/67 chimaeric molecules wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::515f00ccecc86210873ad5d169e06017
http://hdl.handle.net/11391/120765

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Thyroiditis in the BB rat is associated with lymphopenia but occurs independently of diabetes

Autor: Anna Pettersson, Deborah Wilson, Howard J. Jacob, Eric S. Lander, Åke Lernmark, Sarina Tobin, Terri Daniels

Publikováno v: Journal of autoimmunity. 8(4)

The spontaneously diabetic BB rat is an excellent and well studied model for human insulin-dependent diabetes (IDDM), sharing many important features with the human disease. Similarities include an equal frequency of IDDM in males and females, produc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9ec19250ec2d50196e5d75b0334afe3
https://pubmed.ncbi.nlm.nih.gov/7492346

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