Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Terri C. Thayer"'
Autor:
Stephanie J. Hanna, Terri C. Thayer, Emma J. S. Robinson, Ngoc-Nga Vinh, Nigel Williams, Laurie G. Landry, Robert Andrews, Qi Zhuang Siah, Pia Leete, Rebecca Wyatt, Martina A. McAteer, Maki Nakayama, F. Susan Wong, Jennie H. M. Yang, Timothy I. M. Tree, Johnny Ludvigsson, Colin M. Dayan, Danijela Tatovic
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Gold nanoparticles (GNPs) have been used in the development of novel therapies as a way of delivery of both stimulatory and tolerogenic peptide cargoes. Here we report that intradermal injection of GNPs loaded with the proinsulin peptide C19-A3, in p
Externí odkaz:
https://doaj.org/article/53e6f7919fde4d98856728343312e345
Autor:
Dawei Chen, Dimitri Kakabadse, Sigal Fishman, Hadas Weinstein-Marom, Joanne Davies, Joanne Boldison, Terri C. Thayer, Li Wen, Gideon Gross, F. Susan Wong
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionIn this study, we report a novel therapeutic approach using B lymphocytes to attract islet-specific T cells in the non-obese diabetic (NOD) mouse model and prevent the development of autoimmune diabetes. Rather than using the antibody rec
Externí odkaz:
https://doaj.org/article/fbacf4f7fe164db5bbdbb5bcacd5797c
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
In the past few years, huge advances have been made in techniques to analyse cells at an individual level using RNA sequencing, and many of these have precipitated exciting discoveries in the immunology of type 1 diabetes (T1D). This review will cove
Externí odkaz:
https://doaj.org/article/e1afedcb7cb145d4b64a7a796f1d152b
Publikováno v:
Diabetes. 70:955-965
The non-obese diabetic (NOD) mouse develops spontaneous type 1 diabetes, with some features of disease that are very similar to the human disease. However, a proportion of NOD mice are naturally-protected from developing diabetes, and currently studi
Publikováno v:
Diabetes. 70:529-537
Lymph node stromal cells (LNSC) are essential for providing and maintaining peripheral self-tolerance of potentially autoreactive cells. In type 1 diabetes, proinsulin-specific CD8+T-cells, escaping central and peripheral tolerance, contribute to bet
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
In the past few years, huge advances have been made in techniques to analyse cells at an individual level using RNA sequencing, and many of these have precipitated exciting discoveries in the immunology of type 1 diabetes (T1D). This review will cove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::999ea8dd62edd3ea494cbe95d420c1b7
The non-obese diabetic (NOD) mouse develops spontaneous type 1 diabetes, with some features of disease that are very similar to the human disease. However, a proportion of NOD mice are naturally-protected from developing diabetes, and currently studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f65866723d04b1297dbb44324733e20
https://doi.org/10.2337/figshare.13643393.v1
https://doi.org/10.2337/figshare.13643393.v1
Publikováno v:
Methods in Molecular Biology ISBN: 9781071603840
Methods Mol Biol
Methods Mol Biol
There are now a number of different mouse models for type 1 diabetes. The best known is the nonobese diabetic (NOD) mouse which has a genetic susceptibility to autoimmune diabetes with some features that are similar to human type 1 diabetes. The mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c773b638ee18a45cc766f1e9686ab6c2
https://doi.org/10.1007/978-1-0716-0385-7_6
https://doi.org/10.1007/978-1-0716-0385-7_6
Publikováno v:
Methods in Molecular Biology ISBN: 9781071603840
Type 1 diabetes is an autoimmune disease resulting in the loss of insulin production and, consequently, hyperglycemia. The nonobese diabetic (NOD) mouse develops spontaneous diabetes with considerable similarity to the disease in humans. Immunologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba6c74536cc0b782e13c19c41d1e1953
https://doi.org/10.1007/978-1-0716-0385-7_18
https://doi.org/10.1007/978-1-0716-0385-7_18
Autor:
Terri C, Thayer, Joanne, Davies, James A, Pearson, Stephanie J, Hanna, Li, Wen, F Susan, Wong
Publikováno v:
Diabetes
Lymph node stromal cells (LNSC) are essential for providing and maintaining peripheral self-tolerance of potentially autoreactive cells. In type 1 diabetes, proinsulin-specific CD8(+) T cells, escaping central and peripheral tolerance, contribute to