Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Terri A. Pietka"'
Autor:
Yeawon Kim, Chuang Li, Chenjian Gu, Yili Fang, Eric Tycksen, Anuradhika Puri, Terri A. Pietka, Jothilingam Sivapackiam, Kendrah Kidd, Sun-Ji Park, Bryce G. Johnson, Stanislav Kmoch, Jeremy S. Duffield, Anthony J. Bleyer, Meredith E. Jackrel, Fumihiko Urano, Vijay Sharma, Maria Lindahl, Ying Maggie Chen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Misfolded protein aggregates may cause toxic proteinopathy, including autosomal dominant tubulointerstitial kidney disease due to uromodulin mutations (ADTKD-UMOD), a leading hereditary kidney disease. There are no targeted therapies. In our
Externí odkaz:
https://doaj.org/article/72c2d4d2fcd54509bc61bc5046fee857
Autor:
Vincenza Cifarelli, Ondrej Kuda, Kui Yang, Xinping Liu, Richard W. Gross, Terri A. Pietka, Gyu Seong Heo, Deborah Sultan, Hannah Luehmann, Josie Lesser, Morgan Ross, Ira J. Goldberg, Robert J. Gropler, Yongjian Liu, Nada A. Abumrad
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
CD36 mediates the uptake of long-chain fatty acids (FAs), a major energy substrate for the myocardium. Under excessive FA supply, CD36 can cause cardiac lipid accumulation and inflammation while its deletion reduces heart FA uptake and lipid content
Externí odkaz:
https://doaj.org/article/bfbdb0257f3749e7ad0b6d0009d78f34
Autor:
Vincenza Cifarelli, Stoyan Ivanov, Yan Xie, Ni-Huiping Son, Brian T. Saunders, Terri A. Pietka, Trevor M. Shew, Jun Yoshino, Sinju Sundaresan, Nicholas O. Davidson, Ira J. Goldberg, Andrew E. Gelman, Bernd H. Zinselmeyer, Gwendalyn J. Randolph, Nada A. Abumrad
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 3, Iss 1, Pp 82-98 (2017)
Background & Aims: CD36 has immunometabolic actions and is abundant in the small intestine on epithelial, endothelial, and immune cells. We examined the role of CD36 in gut homeostasis by using mice null for CD36 (CD36KO) and with CD36 deletion speci
Externí odkaz:
https://doaj.org/article/993ebac733924e7e98ea9013188fb165
Autor:
Angela M. Hall, Kou Kou, Zhouji Chen, Terri A. Pietka, Mrudula Kumar, Kevin M. Korenblat, Kyuha Lee, Kay Ahn, Elisa Fabbrini, Samuel Klein, Bryan Goodwin, Brian N. Finck
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 5, Pp 990-999 (2012)
Intrahepatic lipid accumulation is extremely common in obese subjects and is associated with the development of insulin resistance and diabetes. Hepatic diacylglycerol and triacylglycerol synthesis predominantly occurs through acylation of glycerol-3
Externí odkaz:
https://doaj.org/article/c64e037f6cf7413fb716e2bfd4d289cb
Autor:
Jason M. Singer, Trevor M. Shew, Daniel Ferguson, M. Katie Renkemeyer, Terri A. Pietka, Angela M. Hall, Brian N. Finck, Andrew J. Lutkewitte
Publikováno v:
Obesity. 30:2122-2133
Monoacylglycerol O-acyltransferase 1 (Mogat1), a lipogenic enzyme that converts monoacylglycerol to diacylglycerol, is highly expressed in adipocytes and may regulate lipolysis by re-esterifying fatty acids released during times when lipolytic rates
Autor:
Terri A. Pietka, Nada A. Abumrad
Publikováno v:
Thermogenic Fat ISBN: 9781071631669
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0181e18f09cc1f79fb93b5e373c83609
https://doi.org/10.1007/978-1-0716-3167-6_4
https://doi.org/10.1007/978-1-0716-3167-6_4
Publikováno v:
Diabetes
Two-thirds of people with type 2 diabetes mellitus (T2DM) have or will develop chronic kidney disease (CKD), which is characterized by rapid renal decline that, together with superimposed T2DM-related metabolic sequelae, synergistically promotes earl
Autor:
Jason M. Singer, Trevor M. Shew, Daniel Ferguson, M. Katie Renkemeyer, Terri A. Pietka, Angela M. Hall, Brian N. Finck, Andrew J. Lutkewitte
ObjectiveMonoacylglycerol O-acyltransferase 1 (Mogat1), a lipogenic enzyme that converts monoacylglycerol to diacylglycerol, is highly expressed in adipocytes and may regulate lipolysis by re-esterifying fatty acids released during times when lipolyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3486f04cb760099ecd8d9b0fe907d949
https://doi.org/10.1101/2022.02.14.480414
https://doi.org/10.1101/2022.02.14.480414
Autor:
Dmitri Samovski, Terri A. Pietka, Hei-Yong G. Lo, Andrea Varro, Eric R. Gamazon, James R. Goldenring, Nada A. Abumrad, Ondrej Kuda, Jason C. Mills, Miriam Jacome-Sosa, Edward F. Morris, Ramkumar Narendran, Vivek S. Peche, Latisha Love-Gregory, Kathryn M. Pietka, Zhi-Feng Miao
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications Biology
Communications Biology
The gastric epithelium is often exposed to injurious elements and failure of appropriate healing predisposes to ulcers, hemorrhage, and ultimately cancer. We examined the gastric function of CD36, a protein linked to disease and homeostasis. We used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9567846779987b00339b4d3ca3dea53d
https://www.repository.cam.ac.uk/handle/1810/332214
https://www.repository.cam.ac.uk/handle/1810/332214
Autor:
Terri A. Pietka, Bettina Mittendorfer, Robert J. Gropler, Babak Razani, Gretchen A. Meyer, Richard Laforest, Stephan van Vliet, Han-Chow E. Koh
Publikováno v:
Diabetes
We used stable isotope-labeled glucose and palmitate tracer infusions, a hyperinsulinemic-euglycemic clamp, positron-emission tomography of muscles and adipose tissue after [18F]fluorodeoxyglucose and [15O]water injections, and subcutaneous adipose t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f20653451595b2b86365b90cc412f7a
https://doi.org/10.2337/figshare.14939088.v1
https://doi.org/10.2337/figshare.14939088.v1