Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Terrence Kantner"'
Autor:
Nick Evans, Ruslan Grygorash, Paul Williams, Andrew Kyle, Terrence Kantner, Ravindra Pathak, XiaoBo Sheng, Fabio Simoes, Hiteshri Makwana, Ricardo Resende, Elena de Juan, Alan Jenkins, David Morris, Aurelie Michelet, Frances Jewitt, Felicity Rudge, Nicolas Camper, Anaïs Manin, William McDowell, Martin Pabst, Antony Godwin, Mark Frigerio, Matthew Bird
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Antibody-drug conjugates (ADCs) have begun to fulfil their promise as targeted cancer therapeutics with ten clinical approvals to date. As the field matures, much attention has focused upon the key factors required to produce safe and efficacious ADC
Externí odkaz:
https://doaj.org/article/e322c470d7fb4d25b6de4ac481fa6602
Publikováno v:
ACS Omega, Vol 2, Iss 9, Pp 5785-5791 (2017)
Externí odkaz:
https://doaj.org/article/fd0b7af5c6eb4cd8a84d257e6d1dbe50
Autor:
Nick, Evans, Ruslan, Grygorash, Paul, Williams, Andrew, Kyle, Terrence, Kantner, Ravindra, Pathak, XiaoBo, Sheng, Fabio, Simoes, Hiteshri, Makwana, Ricardo, Resende, Elena, de Juan, Alan, Jenkins, David, Morris, Aurelie, Michelet, Frances, Jewitt, Felicity, Rudge, Nicolas, Camper, Anaïs, Manin, William, McDowell, Martin, Pabst, Antony, Godwin, Mark, Frigerio, Matthew, Bird
Publikováno v:
Frontiers in pharmacology. 13
Antibody-drug conjugates (ADCs) have begun to fulfil their promise as targeted cancer therapeutics with ten clinical approvals to date. As the field matures, much attention has focused upon the key factors required to produce safe and efficacious ADC
Autor:
Andrew G. Watts, Terrence Kantner
Publikováno v:
Watts, A & Kantner, T 2016, ' Characterization of reactions between water soluble trialkylphosphines and thiol alkylating reagents : implications for protein-conjugation reactions ', Bioconjugate Chemistry, vol. 27, no. 10, pp. 2400-2406 . https://doi.org/10.1021/acs.bioconjchem.6b00375
Water soluble trialkylphosphines such as tris(carboxyethyl)phosphine (TCEP) and trishydroxypropyl phosphine (THPP) are effective agents for reducing disulfide bonds in proteins and are increasingly becoming the reagents of choice for bioconjugation s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c406d872eae5cd9afbe4457b92af23
https://purehost.bath.ac.uk/ws/files/147542302/Bioconj_Chem_Manuscrip.pdf
https://purehost.bath.ac.uk/ws/files/147542302/Bioconj_Chem_Manuscrip.pdf
Publikováno v:
ChemBioChem. 11:533-538
Thioglycoligases are engineered enzymes for the synthesis of thioglycosides that are derived from retaining glycosidases by replacing the acid/base catalyst. The optimal choice of substitution for the acid/base mutant is currently unknown, so to inve
Publikováno v:
Journal of Molecular Biology. 373:337-354
Bacillus circulans xylanase (BcX) is a single-domain family 11 glycoside hydrolase. Using NMR-monitored titrations, we discovered that an inactive variant of this enzyme, E78Q-BcX, bound xylooligosaccharides not only within its pronounced active site
Publikováno v:
ChemBioChem. 11:441-441