Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Terrence Grady"'
Autor:
Abraham P. Zimelman, Nikhil C. Munshi, Paulette Mehta, Rao Prabhala, Alan Lichtenstein, Caroline Behler, Catherine Klein, Terrence Grady, Yvonne A. Efebera, Saem Lee, Teresa G. Hayes, Abid Mohiuddin, Suman Kambhampati, Michal G. Rose, Sarvari Venkata Yellapragada, Andrew J Han, Antoun Houranieh, G. D. Roodman, Saulius K. Girnius
Publikováno v:
British Journal of Haematology. 169:36-43
Summary Once-weekly administration of bortezomib has reduced bortezomib-induced peripheral neuropathy without affecting response rates, but this has only been demonstrated prospectively in three- and four- drug combinations. We report a phase II tria
Autor:
Janese Trimaldi, Ling Zhang, Steven J. Agosti, Loveleen Kang, Alan F. List, Estrella M. Carballido, Bijal D. Shah, Jeremy W. Bowers, Zhong J. Zhang, Salvador Bruno, Terrence Grady, Lynn C. Moscinski, Arturo Anguiano
Publikováno v:
Acta Haematologica. 130:127-134
Myeloid and lymphoid neoplasms with fibroblastic growth factor receptor-1 (FGFR1) abnormalities originate from mutated pluripotent stem cells and have a heterogeneous clinical presentation. There are 12 identified partner genes commonly involved in F
Autor:
Pierluigi Porcu, Larisa J. Geskin, Terrence Grady, Robert A. Baiocchi, Lapo Alinari, Mark A. Bechtel
Publikováno v:
Leukemia Research. 32:1299-1303
Sézary Syndrome (SS) is an aggressive T-cell malignancy often presenting in advanced age and associated with poor prognosis. There is no standard therapy and because of co-morbidities, elderly patients are particularly challenging to treat. Alemtuzu
Publikováno v:
Biochemical and Biophysical Research Communications. 227:1-7
We compared the cellular events induced by hyperstimulation of rats with caerulein which induces acute pancreatitis, to bombesin, which does not induce pancreatitis. Both secretogogues induced the intracellular activation of trypsinogen and the coloc
Publikováno v:
Journal of Biological Chemistry. 271:5686-5690
Stimulation of pancreatic acini from male Sprague-Dawley rats by both cholecystokinin (CCK)-8 and anisomycin caused an increase in p46jnk and p55jnk activities. Both forms of c-Jun amino-terminal kinase (JNK) were slightly activated at 5 min, reached
Autor:
Janese, Trimaldi, Estrella M, Carballido, Jeremy W, Bowers, Arturo L, Anguiano, Zhong J, Zhang, Bijal D, Shah, Salvador, Bruno, Alan F, List, Lynn C, Moscinski, Terrence, Grady, Steven J, Agosti, Loveleen, Kang, Ling, Zhang
Publikováno v:
Acta haematologica. 130(3)
Myeloid and lymphoid neoplasms with fibroblastic growth factor receptor-1 (FGFR1) abnormalities originate from mutated pluripotent stem cells and have a heterogeneous clinical presentation. There are 12 identified partner genes commonly involved in F
Publikováno v:
Gastroenterology. 113(6)
BACKGROUND & AIMS: The molecular mechanisms underlying pancreatitis are largely unknown. The goal of this study was to identify an early genetic event that correlated with pancreatitis. METHODS: Differential display of messenger RNAs (mRNAs) was cond
Autor:
John A. Williams, Guy E. Groblewski, Terrence Grady, Neil Mehta, Craig D. Logsdon, H Lambert, J Landry
Publikováno v:
Gastroenterology. 112(4)
BACKGROUND & AIMS: Mammalian heat shock protein 27 (hsp27) is believed to function under normal physiological conditions and during cellular stress. Recent studies indicate a role for hsp27 in regulating actin- cytoskeletal dynamics. In the present s
Autor:
Antoun Houranieh, Sarvari Venkata Yellapragada, Mary Brophy, Abid Mohiuddin, Abraham P. Zimelman, Michal G. Rose, David Roodman, Saem Lee, Suman Kambhampati, Terrence Grady, Yvonne Efebera, Alan Lichtenstein, Caroline Behler, Catherine Klein, Nikhil C. Munshi, Andrew Han, Teresa G. Hayes, Rao Prabhala, Paulette Mehta
Publikováno v:
Blood. 118:3964-3964
Abstract 3964 Background: Bortezomib in combination with dexamethsone is administered twice a week for 2 weeks with excellent therapeutic outcome. However, in a proportion of patients it is associated with toxicities such as neuropathy and twice a we
Autor:
Y. A. Efebera, Teresa G. Hayes, Alan Lichtenstein, Stephanie J. Lee, Terrence Grady, A. Han, Michal G. Rose, Abid Mohiuddin, Rao Prabhala, Mary Brophy, Paulette Mehta, Antoun Houranieh, Suman Kambhampati, Caroline Behler, G. D. Roodman, Abraham P. Zimelman, Nikhil C. Munshi, Christoph Klein
Publikováno v:
Journal of Clinical Oncology. 29:8074-8074
8074^ Background: The current BZ regimen administered twice a week for 2 weeks with one week off is effective, however is inconvenient and associated with toxicities such as neuropathy. To improve ...