Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Terreia S. Jones"'
Autor:
Tatsuya Ozawa, Sonali Arora, Frank Szulzewsky, Gordana Juric-Sekhar, Yoshiteru Miyajima, Hamid Bolouri, Yoshie Yasui, Jason Barber, Robert Kupp, James Dalton, Terreia S. Jones, Mitsutoshi Nakada, Toshihiro Kumabe, David W. Ellison, Richard J. Gilbertson, Eric C. Holland
Publikováno v:
Cell Reports, Vol 23, Iss 13, Pp 3787-3797 (2018)
Summary: The majority of supratentorial ependymomas (ST-ependymomas) have few mutations but frequently display chromothripsis of chromosome 11q that generates a fusion between C11orf95 and RELA (RELAFUS). Neural stem cells transduced with RELAFUS ex
Externí odkaz:
https://doaj.org/article/0da2b939b999460a98f171b1774b9c97
Autor:
Mitsutoshi Nakada, Toshihiro Kumabe, Jason Barber, Frank Szulzewsky, Yoshie Yasui, Gordana Juric-Sekhar, James Dalton, Hamid Bolouri, Robert Kupp, Richard J. Gilbertson, Yoshiteru Miyajima, Eric C. Holland, Tatsuya Ozawa, Terreia S. Jones, David W. Ellison, Sonali Arora
Publikováno v:
Cell Reports, Vol 23, Iss 13, Pp 3787-3797 (2018)
Cell reports
Cell reports
SUMMARY The majority of supratentorial ependymomas (ST-ependymomas) have few mutations but frequently display chromothripsis of chromosome 11q that generates a fusion between C11orf95 and RELA (RELAFUS). Neural stem cells transduced with RELAFUS ex v
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29163 (2011)
Thiopurine methyltransferase (Tpmt) is the primary enzyme responsible for deactivating thiopurine drugs. Thiopurine drugs (i.e., thioguanine [TG], mercaptopurine, azathioprine) are commonly used for the treatment of cancer, organ transplant, and auto
Externí odkaz:
https://doaj.org/article/120ab4c6711a4671bb3b6dd8b4ce8a9a
Autor:
Amira Hosni-Ahmed, Charles Dai, Bettina Hentschel, Christopher A. Barker, Kenneth L. Pitter, Dolores Hambardzumyan, Kathryn Beal, Tatsuya Ozawa, Roger Stupp, Siobhan S. Pattwell, Shannon Donnola, Kristina Alikhanyan, Timothy A. Chan, Thierry Gorlia, Maria Chang, Ilaria Tamagno, Eric C. Holland, Andrew J. Bishop, Terreia S. Jones, Michael Weller, Uwe Schlegel
Publikováno v:
Brain. 139:1458-1471
Glioblastoma is the most common and most aggressive primary brain tumour. Standard of care consists of surgical resection followed by radiotherapy and concomitant and maintenance temozolomide (temozolomide/radiotherapy→temozolomide). Corticosteroid
Autor:
Shivaputra A. Patil, Renukadevi Patil, Amira Hosni-Ahmed, Lawrence M. Pfeffer, Terreia S. Jones, Duane D. Miller
Publikováno v:
Expert Opinion on Drug Discovery. 8:1135-1151
Gliomas are considered the most malignant form of brain tumors, and ranked among the most aggressive human cancers. Despite advance standard therapy the prognosis for patients with gliomas remains poor. Chemotherapy has played an important role as an
Autor:
Terreia S. Jones, Eric C. Holland
Publikováno v:
Expert Opinion on Drug Discovery. 6:1271-1283
High-grade gliomas are among the most deadly of all cancer types and are also the most common malignant primary tumors of the CNS. Large-scale studies that have analyzed the transcriptional and translational expression patterns of glioma have found t
Autor:
Eric C. Holland, Terreia S. Jones
Publikováno v:
Toxicologic Pathology. 39:158-166
Malignant glial tumors are the most aggressive and difficult to treat neoplasms arising in the brain. More than 22,000 people in the United States are diagnosed with a malignant glioma annually, and most will die within the first two years from diagn
Autor:
Christopher Duntsch, Jon Winestone, Madison Michael, Atul J. Shukla, Umar Akbar, Terreia S. Jones, Yichun Sun
Publikováno v:
Journal of Neuro-Oncology. 94:203-212
Introduction We have completed in vivo safety and efficacy studies of the use of a novel drug delivery system, a gel matrix-temozolomide formulation that is injected intracranially into the post-resection cavity, as a candidate for glioma therapy. Me
Autor:
Wei Liu, Mary V. Relling, Ching-Hon Pui, Cheng Cheng, Wenjian Yang, Terreia S. Jones, Sue C. Kaste, Kelan G. Tantisira
Publikováno v:
Journal of Clinical Oncology. 26:3031-3037
Purpose Corticosteroids are a critical component of therapy for acute lymphoblastic leukemia (ALL) but are associated with late effects, such as osteoporosis. Risk factors remain poorly defined. Because CRHR1 polymorphisms have been associated with o
Autor:
Christopher Duntsch, Peter Boehm, George C. Wood, Bob M. Moore, Terreia S. Jones, Allen K. Sills, Mathangi Krishnamurthy, Qihong Zhou, Murali Krishna Divi
Publikováno v:
Journal of Neuro-Oncology. 77:143-152
To test in vitro and in vivo the safety and efficacy of a novel chemotherapeutic agent, KM-233, for the treatment of glioma.In vitro cell cytotoxicity assays were used to measure and compare the cytotoxic effects of KM-233, Delta(8)-tetrahydrocannabi